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Publications

featured publications

  • Kupffer Cells Sense Free Fatty Acids and Regulate Hepatic Lipid Metabolism in High-Fat Diet and Inflammation.

    Cells

    Authors: Kira L Diehl, Julia Vorac, Kristina Hofmann, Philippa Meiser, Iris Unterweger, Lars Kuerschner, Heike Weighardt, Irmgard Förster, Christoph Thiele

  • Enhanced lipid biosynthesis in human tumor-induced macrophages contributes to their protumoral characteristics.

    Journal for immunotherapy of cancer

    Authors: Katrin Rabold, Anna Aschenbrenner, Christoph Thiele, Collins K Boahen, Alexander Schiltmans, Johannes W A Smit, Joachim L Schultze, Mihai G Netea, Gosse J Adema, Romana T Netea-Maier

  • 1-Deoxysphingolipids cause autophagosome and lysosome accumulation and trigger NLRP3 inflammasome activation.

    Autophagy

    Authors: Mario A Lauterbach, Victor Saavedra, Matthew S J Mangan, Anke Penno, Christoph Thiele, Eicke Latz, Lars Kuerschner

  • Free fatty acid determination as a tool for modeling metabolic diseases in Drosophila.

    Journal of insect physiology

    Authors: Julia Sellin, Judith B Fülle, Christoph Thiele, Reinhard Bauer, Margret H Bülow

  • Molecular profiling of lipid droplets inside HuH7 cells with Raman micro-spectroscopy.

    Communications biology

    Authors: Ashok Zachariah Samuel, Rimi Miyaoka, Masahiro Ando, Anne Gaebler, Christoph Thiele, Haruko Takeyama

  • Importance of γ-secretase in the regulation of liver X receptor and cellular lipid metabolism.

    Life science alliance

    Authors: Esteban Gutierrez, Dieter Lütjohann, Anja Kerksiek, Marietta Fabiano, Naoto Oikawa, Lars Kuerschner, Christoph Thiele, Jochen Walter

  • Top publication

    Lipid-Droplet Formation Drives Pathogenic Group 2 Innate Lymphoid Cells in Airway Inflammation.

    Immunity

    Authors: Fotios Karagiannis, Schekufe Kharabi Masouleh, Klaus Wunderling, Jayagopi Surendar, Vanessa Schmitt, Alexander Kazakov, Marcel Michla, Michael Hölzel, Christoph Thiele, Christoph Wilhelm

  • Photoactivable Cholesterol as a Tool to Study Interaction of Influenza Virus Hemagglutinin with Cholesterol.

    Bio-protocol

    Authors: Bodan Hu, Mohamed Rasheed Gadalla, Christoph Thiele, Michael Veit

  • Multiplexed and single cell tracing of lipid metabolism.

    Nature methods

    Authors: Christoph Thiele, Klaus Wunderling, Philipp Leyendecker

  • Human PNPLA3-I148M variant increases hepatic retention of polyunsaturated fatty acids.

    JCI insight

    Authors: Panu K Luukkonen, Auli Nick, Maarit Hölttä-Vuori, Christoph Thiele, Elina Isokuortti, Susanna Lallukka-Brück, You Zhou, Antti Hakkarainen, Nina Lundbom, Markku Peltonen, Marju Orho-Melander, Matej Orešič, Tuulia Hyötyläinen, Leanne Hodson, Elina Ikonen, Hannele Yki-Järvinen