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featured publications

  • Alveolar macrophage transcriptomic profiling in COPD shows major lipid metabolism changes.

    ERJ open research

    Authors: Wataru Fujii, Theodore S Kapellos, Kevin Baßler, Kristian Händler, Lisa Holsten, Rainer Knoll, Stefanie Warnat-Herresthal, Marie Oestreich, Emily R Hinkley, Jan Hasenauer, Carmen Pizarro, Christoph Thiele, Anna C Aschenbrenner, Thomas Ulas, Dirk Skowasch, Joachim L Schultze

  • An advanced method for propargylcholine phospholipid detection by direct-infusion MS.

    Journal of lipid research

    Authors: Mohamed H Yaghmour, Christoph Thiele, Lars Kuerschner

  • Hepatic synthesis of triacylglycerols containing medium-chain fatty acids is dominated by diacylglycerol acyltransferase 1 and efficiently inhibited by etomoxir.

    Molecular metabolism

    Authors: Klaus Wunderling, Christina Leopold, Isabell Jamitzky, Mohamed Yaghmour, Fabian Zink, Dagmar Kratky, Christoph Thiele

  • Generation of immune cell containing adipose organoids for in vitro analysis of immune metabolism.

    Scientific reports

    Authors: Jacqueline Taylor, Julia Sellin, Lars Kuerschner, Lennart Krähl, Yasmin Majlesain, Irmgard Förster, Christoph Thiele, Heike Weighardt, Elvira Weber

  • Kupffer Cells Sense Free Fatty Acids and Regulate Hepatic Lipid Metabolism in High-Fat Diet and Inflammation.

    Cells

    Authors: Kira L Diehl, Julia Vorac, Kristina Hofmann, Philippa Meiser, Iris Unterweger, Lars Kuerschner, Heike Weighardt, Irmgard Förster, Christoph Thiele

  • Enhanced lipid biosynthesis in human tumor-induced macrophages contributes to their protumoral characteristics.

    Journal for immunotherapy of cancer

    Authors: Katrin Rabold, Anna Aschenbrenner, Christoph Thiele, Collins K Boahen, Alexander Schiltmans, Johannes W A Smit, Joachim L Schultze, Mihai G Netea, Gosse J Adema, Romana T Netea-Maier

  • 1-Deoxysphingolipids cause autophagosome and lysosome accumulation and trigger NLRP3 inflammasome activation.

    Autophagy

    Authors: Mario A Lauterbach, Victor Saavedra, Matthew S J Mangan, Anke Penno, Christoph Thiele, Eicke Latz, Lars Kuerschner

  • Free fatty acid determination as a tool for modeling metabolic diseases in Drosophila.

    Journal of insect physiology

    Authors: Julia Sellin, Judith B Fülle, Christoph Thiele, Reinhard Bauer, Margret H Bülow

  • Molecular profiling of lipid droplets inside HuH7 cells with Raman micro-spectroscopy.

    Communications biology

    Authors: Ashok Zachariah Samuel, Rimi Miyaoka, Masahiro Ando, Anne Gaebler, Christoph Thiele, Haruko Takeyama

  • Importance of γ-secretase in the regulation of liver X receptor and cellular lipid metabolism.

    Life science alliance

    Authors: Esteban Gutierrez, Dieter Lütjohann, Anja Kerksiek, Marietta Fabiano, Naoto Oikawa, Lars Kuerschner, Christoph Thiele, Jochen Walter