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  • Kupffer cells control neonatal hepatic metabolism via Igf1 signaling.

    Development (Cambridge, England)

    Authors: Nikola Makdissi, Daria Hirschmann, Aleksej Frolov, Inaam Sado, Bastian Bennühr, Fabian Nikolka, Jingyuan Cheng, Nelli Blank-Stein, Maria Francesca Viola, Mohamed Yaghmour, Philipp Arnold, Lorenzo Bonaguro, Matthias Becker, Christoph Thiele, Felix Meissner, Karsten Hiller, Marc D Beyer, Elvira Mass

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  • High-salt diet induces immune-independent re-differentiation, metabolic shut down and cell cycle arrest of melanoma.

    Cell death & disease

    Authors: Clivia Lisowski, Natascha E Stumpf, Katarzyna Jobin, Daniela Klaus, Melanie Eichler, Ann-Kathrin Baumgart, Olena Babyak, Mirjam Meißner, Agnes Schröder, Patrick Neubert, Vanessa Schmitt, Marcel Michla, Süleyman Bozkurt, Jelena Zurkovic, Daniel Hinze, Jana Liebing, Matthias Eckhardt, Christoph Heuser, Lea Seep, Annkristin Heine, Janine Becker-Gotot, Christoph Thiele, Christian Münch, Thomas Becker, Jonathan Jantsch, Christoph Wilhelm, Michael Hölzel, Christian Kurts

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  • Tolerance to ferroptosis facilitates lipid metabolism and pathogenic type 2 immunity in allergic airway inflammation.

    Immunity

    Authors: Chantal Wientjens, Maria Doverman, Jelena Zurkovic, Tushar More, Jayagopi Surendar, Svetozar Nesic, Carola Sarici, Timon D Utecht, Johanna Pohl, Jonathan Pollock, David Voehringer, Karsten Hiller, Christoph Thiele, Christoph Wilhelm

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  • Individual lipid alterations at the origin of neuronal Ceramide Synthase defects.

    PLoS genetics

    Authors: Anna B Ziegler, Cedrik Wesselmann, Konstantin Beckschäfer, Anna-Lena Wulf, Neena Dhiman, Peter Soba, Christoph Thiele, Reinhard Bauer, Gaia Tavosanis

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  • Global matrisome changes in obese lung are linked to fibroblastic stroma and premature aging.

    Cell reports

    Authors: Sophia Rottmann, Jian Li, Jelena Zurkovic, Pablo S Bravo, Andreas U Lindner, Jie Qin, Sebastian Kallabis, Qi Mei, Xiansheng Liu, Christoph Thiele, Christoph Eckert, Felix Meissner, Veronika Lukacs-Kornek

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  • Control of Golgi- V-ATPase through Sac1-dependent co-regulation of PI(4)P and cholesterol.

    Nature communications

    Authors: Xin Zhou, Miesje M van der Stoel, Shreyas Kaptan, Haoran Li, Shiqian Li, Maarit Hölttä, Helena Vihinen, Eija Jokitalo, Christoph Thiele, Olli Pietiläinen, Shin Morioka, Junko Sasaki, Takehiko Sasaki, Ilpo Vattulainen, Elina Ikonen

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  • BBS8-dependent ciliary Hedgehog signaling governs cell fate in the white adipose tissue.

    The EMBO journal

    Authors: Katharina Sieckmann, Nora Winnerling, Dalila Juliana Silva Ribeiro, Seniz Yüksel, Ronja Kardinal, Lisa Maria Steinheuer, Fabian Frechen, Luis Henrique Corrêa, Geza Schermann, Christina Klausen, Nelli Blank-Stein, Jonas Schulte-Schrepping, Collins Osei-Sarpong, Matthias Becker, Lorenzo Bonaguro, Marc Beyer, Helen Louise May-Simera, Jelena Zurkovic, Christoph Thiele, Kevin Thurley, Lydia Sorokin, Carmen Ruiz de Almodovar, Elvira Mass, Dagmar Wachten

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  • Phosphatidylcholine synthesis and remodeling in brain endothelial cells.

    Journal of lipid research

    Authors: Mohamed H Yaghmour, Theja Sajeevan, Christoph Thiele, Lars Kuerschner

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  • Differential cell type-specific function of the aryl hydrocarbon receptor and its repressor in diet-induced obesity and fibrosis.

    Molecular metabolism

    Authors: Frederike J Graelmann, Fabian Gondorf, Yasmin Majlesain, Birte Niemann, Katarina Klepac, Dominic Gosejacob, Marlene Gottschalk, Michelle Mayer, Irina Iriady, Philip Hatzfeld, Sophie K Lindenberg, Klaus Wunderling, Christoph Thiele, Zeinab Abdullah, Wei He, Karsten Hiller, Kristian Händler, Marc D Beyer, Thomas Ulas, Alexander Pfeifer, Charlotte Esser, Heike Weighardt, Irmgard Förster, Laia Reverte-Salisa

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  • Triglyceride cycling enables modification of stored fatty acids.

    Nature metabolism

    Authors: Klaus Wunderling, Jelena Zurkovic, Fabian Zink, Lars Kuerschner, Christoph Thiele

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