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featured publications

  • Size-dependent plastic exposure disrupts macrophage function and tissue-specific metabolism.

    Nature metabolism

    Authors: Nikola Makdissi, Maria Francesca Viola, Lisa Maria Steinheuer, Nelli Blank-Stein, Ronja Kardinal, Fabrizio Musacchio, Eliana Franco Taveras, Virginia Aliprandi, Katharina Sieckmann, Akram Abdulkadyrov, Marina L Mayer, Marie-Louise Diefenbach-Wilke, Diana Fink, Hannes Beckert, Stefan Böhmdorfer, Quentin Deveuve, Frederike J Graelmann, Katharina Mauel, Nele Kronau, Jake Thomas, David Bejarano, Andreas Schlitzer, Sandra Högler, Mohamed H Yaghmour, Joerg Heeren, Christoph Thiele, Lukas Kenner, Felix Meissner, Falk Nimmerjahn, Martin Fuhrmann, Dagmar Wachten, Kevin Thurley, Elvira Mass

  • The fruitfly Drosophila melanogaster as an in vivo model of ferroptosis.

    Redox biology

    Authors: Li Zhang, Felix Schmidt, Fatih Yasar, Yasminn Akele, Bernhard Michalke, Konstantin Beckschäfer, Christoph Thiele, Eva-Maria Hanschmann, Vivek Venkataramani, Axel Methner

  • Adipose ILC2s depend on acetyl-CoA carboxylase 1 to maintain metabolic health.

    Cell metabolism

    Authors: Fotios Karagiannis, Maria Rafailia Theodorou, Fabian Nikolka, Maria Doverman, Dhruvi Shah, Chantal Wientjens, Timothy R McCulloch, Ronja Kardinal, David Colon, Jelena Zurkovic, Jiangyan Yu, Julia Anna Noras, Patricia Weiss, Roman Rombo, Tim Sparwasser, Zeinab Abdullah, Felix Meissner, Christoph Thiele, Jan Hasenauer, Dagmar Wachten, Karsten Hiller, Christoph Wilhelm

  • Suggested experimental design and computational modeling to infer single-cell lipid dynamics from a single destructive measurement.

    iScience

    Authors: Paul Jonas Jost, Daniel Weindl, Klaus Wunderling, Christoph Thiele, Jan Hasenauer

  • Cholesterol-lowering effects of oats induced by microbially produced phenolic metabolites in metabolic syndrome: a randomized controlled trial.

    Nature communications

    Authors: Linda Klümpen, Aakash Mantri, Maren Philipps, Waldemar Seel, Laura Schlautmann, Mohamed H Yaghmour, Verena Wiemann, Birgit Stoffel-Wagner, Martin Coenen, Leonie Weinhold, Jan Hasenauer, Thomas Fließwasser, Sven Burgdorf, Christoph Thiele, Peter Stehle, Marie-Christine Simon

  • Alkyne lipids as tracers of lipid metabolism.

    Methods in enzymology

    Authors: Christoph Thiele

  • DGAT-driven futile lipid cycling has a pronounced, yet concealed, thermogenic function.

    Cell metabolism

    Authors: Anand Kumar Sharma, Radhika Khandelwal, Jelena Zurkovic, Fen Long, Tongtong Wang, Revati S Dewal, Chunyan Wu, Adhideb Ghosh, Klug Manuel, Alaa Othman, Chandramohan Chitraju, Robert V Farese, Tobias C Walther, Miroslav Balaz, Christoph Thiele, Christian Wolfrum

  • Kupffer cells control neonatal hepatic metabolism via Igf1 signaling.

    Development (Cambridge, England)

    Authors: Nikola Makdissi, Daria Hirschmann, Aleksej Frolov, Inaam Sado, Bastian Bennühr, Fabian Nikolka, Jingyuan Cheng, Nelli Blank-Stein, Maria Francesca Viola, Mohamed Yaghmour, Philipp Arnold, Lorenzo Bonaguro, Matthias Becker, Christoph Thiele, Felix Meissner, Karsten Hiller, Marc D Beyer, Elvira Mass

  • High-salt diet induces immune-independent re-differentiation, metabolic shut down and cell cycle arrest of melanoma.

    Cell death & disease

    Authors: Clivia Lisowski, Natascha E Stumpf, Katarzyna Jobin, Daniela Klaus, Melanie Eichler, Ann-Kathrin Baumgart, Olena Babyak, Mirjam Meißner, Agnes Schröder, Patrick Neubert, Vanessa Schmitt, Marcel Michla, Süleyman Bozkurt, Jelena Zurkovic, Daniel Hinze, Jana Liebing, Matthias Eckhardt, Christoph Heuser, Lea Seep, Annkristin Heine, Janine Becker-Gotot, Christoph Thiele, Christian Münch, Thomas Becker, Jonathan Jantsch, Christoph Wilhelm, Michael Hölzel, Christian Kurts

  • Tolerance to ferroptosis facilitates lipid metabolism and pathogenic type 2 immunity in allergic airway inflammation.

    Immunity

    Authors: Chantal Wientjens, Maria Doverman, Jelena Zurkovic, Tushar More, Jayagopi Surendar, Svetozar Nesic, Carola Sarici, Timon D Utecht, Johanna Pohl, Jonathan Pollock, David Voehringer, Karsten Hiller, Christoph Thiele, Christoph Wilhelm