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Publications

featured publications

  • Suggested experimental design and computational modeling to infer single-cell lipid dynamics from a single destructive measurement.

    iScience

    Authors: Paul Jonas Jost, Daniel Weindl, Klaus Wunderling, Christoph Thiele, Jan Hasenauer

  • Cholesterol-lowering effects of oats induced by microbially produced phenolic metabolites in metabolic syndrome: a randomized controlled trial.

    Nature communications

    Authors: Linda Klümpen, Aakash Mantri, Maren Philipps, Waldemar Seel, Laura Schlautmann, Mohamed H Yaghmour, Verena Wiemann, Birgit Stoffel-Wagner, Martin Coenen, Leonie Weinhold, Jan Hasenauer, Thomas Fließwasser, Sven Burgdorf, Christoph Thiele, Peter Stehle, Marie-Christine Simon

  • Alkyne lipids as tracers of lipid metabolism.

    Methods in enzymology

    Authors: Christoph Thiele

  • DGAT-driven futile lipid cycling has a pronounced, yet concealed, thermogenic function.

    Cell metabolism

    Authors: Anand Kumar Sharma, Radhika Khandelwal, Jelena Zurkovic, Fen Long, Tongtong Wang, Revati S Dewal, Chunyan Wu, Adhideb Ghosh, Klug Manuel, Alaa Othman, Chandramohan Chitraju, Robert V Farese, Tobias C Walther, Miroslav Balaz, Christoph Thiele, Christian Wolfrum

  • Kupffer cells control neonatal hepatic metabolism via Igf1 signaling.

    Development (Cambridge, England)

    Authors: Nikola Makdissi, Daria Hirschmann, Aleksej Frolov, Inaam Sado, Bastian Bennühr, Fabian Nikolka, Jingyuan Cheng, Nelli Blank-Stein, Maria Francesca Viola, Mohamed Yaghmour, Philipp Arnold, Lorenzo Bonaguro, Matthias Becker, Christoph Thiele, Felix Meissner, Karsten Hiller, Marc D Beyer, Elvira Mass

  • High-salt diet induces immune-independent re-differentiation, metabolic shut down and cell cycle arrest of melanoma.

    Cell death & disease

    Authors: Clivia Lisowski, Natascha E Stumpf, Katarzyna Jobin, Daniela Klaus, Melanie Eichler, Ann-Kathrin Baumgart, Olena Babyak, Mirjam Meißner, Agnes Schröder, Patrick Neubert, Vanessa Schmitt, Marcel Michla, Süleyman Bozkurt, Jelena Zurkovic, Daniel Hinze, Jana Liebing, Matthias Eckhardt, Christoph Heuser, Lea Seep, Annkristin Heine, Janine Becker-Gotot, Christoph Thiele, Christian Münch, Thomas Becker, Jonathan Jantsch, Christoph Wilhelm, Michael Hölzel, Christian Kurts

  • Tolerance to ferroptosis facilitates lipid metabolism and pathogenic type 2 immunity in allergic airway inflammation.

    Immunity

    Authors: Chantal Wientjens, Maria Doverman, Jelena Zurkovic, Tushar More, Jayagopi Surendar, Svetozar Nesic, Carola Sarici, Timon D Utecht, Johanna Pohl, Jonathan Pollock, David Voehringer, Karsten Hiller, Christoph Thiele, Christoph Wilhelm

  • Individual lipid alterations at the origin of neuronal Ceramide Synthase defects.

    PLoS genetics

    Authors: Anna B Ziegler, Cedrik Wesselmann, Konstantin Beckschäfer, Anna-Lena Wulf, Neena Dhiman, Peter Soba, Christoph Thiele, Reinhard Bauer, Gaia Tavosanis

  • Global matrisome changes in obese lung are linked to fibroblastic stroma and premature aging.

    Cell reports

    Authors: Sophia Rottmann, Jian Li, Jelena Zurkovic, Pablo S Bravo, Andreas U Lindner, Jie Qin, Sebastian Kallabis, Qi Mei, Xiansheng Liu, Christoph Thiele, Christoph Eckert, Felix Meissner, Veronika Lukacs-Kornek

  • Control of Golgi- V-ATPase through Sac1-dependent co-regulation of PI(4)P and cholesterol.

    Nature communications

    Authors: Xin Zhou, Miesje M van der Stoel, Shreyas Kaptan, Haoran Li, Shiqian Li, Maarit Hölttä, Helena Vihinen, Eija Jokitalo, Christoph Thiele, Olli Pietiläinen, Shin Morioka, Junko Sasaki, Takehiko Sasaki, Ilpo Vattulainen, Elina Ikonen