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featured publications

  • TCA metabolism regulates DNA hypermethylation in LPS and -induced immune tolerance.

    Proceedings of the National Academy of Sciences of the United States of America

    Authors: Abhimanyu, Santiago Carrero Longlax, Tomoki Nishiguchi, Malik Ladki, Daanish Sheikh, Amera L Martinez, Emily M Mace, Sandra L Grimm, Thaleia Caldwell, Alexandra Portillo Varela, Rajagopal V Sekhar, Anna M Mandalakas, Mandla Mlotshwa, Sibuse Ginidza, Jeffrey D Cirillo, Robert S Wallis, Mihai G Netea, Reinout van Crevel, Cristian Coarfa, Andrew R DiNardo

  • T lymphocyte recruitment to melanoma brain tumors depends on distinct venous vessels.

    Immunity

    Authors: Julia M Messmer, Calvin Thommek, Manuel Piechutta, Varun Venkataramani, Rebekka Wehner, Dana Westphal, Marc Schubert, Chanté D Mayer, Maike Effern, Anna S Berghoff, Daniel Hinze, Iris Helfrich, Dirk Schadendorf, Wolfgang Wick, Michael Hölzel, Matthia A Karreman, Frank Winkler

  • Transient MRI changes and neurological deterioration in glioblastoma upon SARS-CoV-2 infection.

    Journal of cancer research and clinical oncology

    Authors: Thomas Zeyen, Lea L Friker, Daniel Paech, Niklas Schaefer, Johannes Weller, Valentina Zschernack, Julian P Layer, Matthias Schneider, Anna-Laura Potthoff, Marit Bernhardt, Christine Sanders, Glen Kristiansen, Michael Hoelzel, Eleni Gkika, Alexander Radbruch, Torsten Pietsch, Ulrich Herrlinger, Christina Schaub

  • Multimodal profiling of peripheral blood identifies proliferating circulating effector CD4 T cells as predictors for response to integrin α4β7-blocking therapy in inflammatory bowel disease.

    Gastroenterology

    Authors: Veronika Horn, Camila A Cancino, Lisa Maria Steinheuer, Benedikt Obermayer, Konstantin Fritz, Anke L Nguyen, Kim Susan Juhran, Christina Plattner, Diana Bösel, Lotte Oldenburg, Marie Burns, Axel Ronald Schulz, Mariia Saliutina, Eleni Mantzivi, Donata Lissner, Thomas Conrad, Mir-Farzin Mashreghi, Sebastian Zundler, Elena Sonnenberg, Michael Schumann, Lea-Maxie Haag, Dieter Beule, Lukas Flatz, Zlatko Trjanoski, Geert D'Haens, Carl Weidinger, Henrik E Mei, Britta Siegmund, Kevin Thurley, Ahmed N Hegazy

  • Insights into reproduction-regulating NOD-like receptors.

    Nature structural & molecular biology

    Authors: Inga V Hochheiser, Matthias Geyer

  • The impact of lenvatinib on sarcopenia in patients with advanced unresectable hepatocellular carcinoma.

    Scientific reports

    Authors: Michael Praktiknjo, Ana S Pena Solano, Farsaneh Sadeghlar, Thomas Welchowski, Matthias Schmid, Christian Möhring, Taotao Zhou, Robert Mahn, Malte B Monin, Carsten Meyer, Georg Feldmann, Peter Brossart, Cornelius van Beekum, Alexander Semaan, Hanno Matthaei, Steffen Manekeller, Alois M Sprinkart, Sebastian Nowak, Julian Luetkens, Jörg C Kalff, Christian P Strassburg, Maria A González-Carmona

  • [What is confirmed in therapy of complicated urinary tract infections].

    Innere Medizin (Heidelberg, Germany)

    Authors: Sibylle von Vietinghoff, Florian Wagenlehner

  • Clinical and Market Analysis of NanoBEO: A Public-Worth, Innovative Therapy for Behavioral and Psychological Symptoms of Dementia (BPSD)-Emerging Evidence and Its Implications for a Health Technology Assessment (HTA) and Decision-Making in National …

    Pharmaceutics

    Authors: Damiana Scuteri, Daniele Pierobon, Martina Pagliaro, Kengo Hamamura, Takafumi Hayashi, Loris Pignolo, Pierluigi Nicotera, Giacinto Bagetta, Maria Tiziana Corasaniti

  • Systemic dysregulation and molecular insights into poor influenza vaccine response in the aging population.

    Science advances

    Authors: Saumya Kumar, Martijn Zoodsma, Nhan Nguyen, Rodrigo Pedroso, Stephanie Trittel, Peggy Riese, Javier Botey-Bataller, Liang Zhou, Ahmed Alaswad, Haroon Arshad, Mihai G Netea, Cheng-Jian Xu, Frank Pessler, Carlos A Guzmán, Luis Graca, Yang Li

  • Antagonistic nanobodies implicate mechanism of GSDMD pore formation and potential therapeutic application.

    Nature communications

    Authors: Lisa D J Schiffelers, Yonas M Tesfamariam, Lea-Marie Jenster, Stefan Diehl, Sophie C Binder, Sabine Normann, Jonathan Mayr, Steffen Pritzl, Elena Hagelauer, Anja Kopp, Assaf Alon, Matthias Geyer, Hidde L Ploegh, Florian I Schmidt