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featured publications

  • Hypothalamic volume is associated with age, sex and cognitive function across lifespan: a comparative analysis of two large population-based cohort studies.

    EBioMedicine

    Authors: Peng Xu, Santiago Estrada, Rika Etteldorf, Dan Liu, Mohammad Shahid, Weiyi Zeng, Deborah Früh, Martin Reuter, Monique M B Breteler, N Ahmad Aziz

  • Reliability of high-quantity human brain organoids for modeling microcephaly, glioma invasion and drug screening.

    Nature communications

    Authors: Anand Ramani, Giovanni Pasquini, Niklas J Gerkau, Vaibhav Jadhav, Omkar Suhas Vinchure, Nazlican Altinisik, Hannes Windoffer, Sarah Muller, Ina Rothenaigner, Sean Lin, Aruljothi Mariappan, Dhanasekaran Rathinam, Ali Mirsaidi, Olivier Goureau, Lucia Ricci-Vitiani, Quintino Giorgio D'Alessandris, Bernd Wollnik, Alysson Muotri, Limor Freifeld, Nathalie Jurisch-Yaksi, Roberto Pallini, Christine R Rose, Volker Busskamp, Elke Gabriel, Kamyar Hadian, Jay Gopalakrishnan

  • Unveiling the power of high-dimensional cytometry data with cyCONDOR.

    Nature communications

    Authors: Charlotte Kröger, Sophie Müller, Jacqueline Leidner, Theresa Kröber, Stefanie Warnat-Herresthal, Jannis Bastian Spintge, Timo Zajac, Anna Neubauer, Aleksej Frolov, Caterina Carraro, Frank Jessen, Simone Puccio, Anna C Aschenbrenner, Joachim L Schultze, Tal Pecht, Marc D Beyer, Lorenzo Bonaguro

  • Regulation of PDL-1 expression in thyroid carcinoma cells by tumor cell derived cytokines activating STAT3.

    Immunologic research

    Authors: Matthias Klemke, Nadine Veit, Ingo Schmidt-Wolf, Ralph A Bundschuh, Markus Essler, Barbara Kreppel

  • Modulation of Haemostatic Balance in Combined von Willebrand Disease and Antithrombin Deficiency: A Comprehensive Family Study.

    Haemophilia : the official journal of the World Federation of Hemophilia

    Authors: Behnaz Pezeshkpoor, Ronald Fischer, Barbara Preisler, Katrin Hartlieb, Heiko Rühl, Jens Müller, Silvia Horneff, Natascha Marquardt, Anna Pavlova, Johannes Oldenburg

  • Role of ZFHX4 in orofacial clefting based on human genetic data and zebrafish models.

    European journal of human genetics : EJHG

    Authors: Nina Ishorst, Selina Hölzel, Carola Greve, Öznur Yilmaz, Tobias Lindenberg, Jessica Lambertz, Dmitriy Drichel, Berina Zametica, Enrico Mingardo, Jeshurun C Kalanithy, Khadija Channab, Duygu Kibris, Sabrina Henne, Franziska Degenhardt, Anna Siewert, Michael Dixon, Teresa Kruse, Edwin Ongkosuwito, Katta M Girisha, Shruti Pande, Stefanie Nowak, Gregor Hagelueken, Matthias Geyer, Carine Carels, Iris A L M van Rooij, Kerstin U Ludwig, Benjamin Odermatt, Elisabeth Mangold

  • NIS-Seq enables cell-type-agnostic optical perturbation screening.

    Nature biotechnology

    Authors: Caroline I Fandrey, Marius Jentzsch, Peter Konopka, Alexander Hoch, Katja Blumenstock, Afraa Zackria, Salie Maasewerd, Marta Lovotti, Dorothee J Lapp, Florian N Gohr, Piotr Suwara, Jędrzej Świeżewski, Lukas Rossnagel, Fabienne Gobs, Maia Cristodaro, Lina Muhandes, Rayk Behrendt, Martin C Lam, Klaus J Walgenbach, Tobias Bald, Florian I Schmidt, Eicke Latz, Jonathan L Schmid-Burgk

  • Longitudinal Study of SARS-CoV-2 Vaccinations and Infections in Patients with Gastrointestinal Cancer: Stabilizing Immune Responses and Neutralizing Emerging Variants with Variant-Adapted Antigen Exposures.

    International journal of molecular sciences

    Authors: Maria A Gonzalez-Carmona, Alina M Schmitz, Moritz Berger, Leona I Baier, Jens G Gorny, Farsaneh Sadeghlar, Thomas Anhalt, Xin Zhou, Taotao Zhou, Robert Mahn, Christian Möhring, Thomas Linnemann, Matthias Schmid, Christian P Strassburg, Christoph Boesecke, Jürgen K Rockstroh, Anna-Maria Eis-Hübinger, Malte B Monin

  • Impact of COVID-19, lockdowns and vaccination on immune responses in a HIV cohort in the Netherlands.

    Frontiers in immunology

    Authors: Twan Otten, Xun Jiang, Manoj Kumar Gupta, Nadira Vadaq, Maartje Cleophas-Jacobs, Jéssica C Dos Santos, Albert Groenendijk, Wilhelm Vos, Louise E van Eekeren, Marc J T Blaauw, Elise M G Meeder, Olivier Richel, Vasiliki Matzaraki, Jan van Lunzen, Leo A B Joosten, Yang Li, Cheng-Jian Xu, Andre van der Ven, Mihai G Netea

  • Locus coeruleus signal intensity and emotion regulation in agitation in Alzheimer's disease.

    Brain communications

    Authors: Kathy Y Liu, Matthew J Betts, Dorothea Hämmerer, Emrah Düzel, Mara Mather, Jonathan P Roiser, Anja Schneider, Annika Spottke, Ayda Rostamzadeh, Björn H Schott, Boris-Stephan Rauchmann, Christoph Laske, Daniel Janowitz, Eike J Spruth, Ersin Ersözlü, Falk Lüsebrink, Frank Jessen, Ingo Frommann, Ingo Kilimann, Jens Wiltfang, Johanna Brustkern, Josef Priller, Julian Hellman-Regen, Katharina Buerger, Klaus Fliessbach, Klaus Scheffler, Luca Kleineidam, Melina Stark, Michael Ewers, Michael Wagner, Oliver Peters, Peter Dechent, Robert Perneczky, Sebastian Sodenkamp, Stefan Hetzer, Stefan Teipel, Wenzel Glanz, Robert Howard