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Publications

Featured publications

  • Macrofilaricidal Benzimidazole-Benzoxaborole Hybrids as an Approach to the Treatment of River Blindness: Part 1. Amide Linked Analogs.

    ACS infectious diseases

    Authors: Tsutomu Akama, Yvonne R Freund, Pamela W Berry, David S Carter, Eric E Easom, Kurt Jarnagin, Christopher S Lunde, Jacob J Plattner, Fernando Rock, Rianna Stefanakis, Chelsea Fischer, Christina A Bulman, Kee Chong Lim, Brian M Suzuki, Nancy Tricoche, Abdelmoneim Mansour, Utami DiCosty, Scott McCall, Ben Carson, John W McCall, James McKerrow, Marc P Hübner, Sabine Specht, Achim Hoerauf, Sara Lustigman, Judy A Sakanari, Robert T Jacobs

  • Short-course quinazoline drug treatments are effective in the Litomosoides sigmodontis and Brugia pahangi jird models.

    International journal for parasitology. Drugs and drug resistance

    Authors: Marc P Hübner, Emma Gunderson, Ian Vogel, Christina A Bulman, K C Lim, Marianne Koschel, Alexandra Ehrens, Stefan J Frohberger, Martina Fendler, Nancy Tricoche, Denis Voronin, Andrew Steven, Victor Chi, Malina A Bakowski, Ashley K Woods, H Michael Petrassi, Case W McNamara, Brenda Beerntsen, Laura Chappell, William Sullivan, Mark J Taylor, Joseph D Turner, Achim Hoerauf, Sara Lustigman, Judy A Sakanari

  • Protection of Batf3-deficient mice from experimental cerebral malaria correlates with impaired cytotoxic T-cell responses and immune regulation.

    Immunology

    Authors: Janina M Kuehlwein, Max Borsche, Patricia J Korir, Frederic Risch, Ann-Kristin Mueller, Marc P Hübner, Kai Hildner, Achim Hoerauf, Ildiko Rita Dunay, Beatrix Schumak

  • TGFβ depletion does neither modulate acute E. coli-induced inflammatory immune responses nor impair the protective effect by chronic filarial infection.

    GMS infectious diseases

    Authors: Benedikt C Buerfent, Jesuthas Ajendra, Wiebke Stamminger, Fabian Gondorf, Achim Hoerauf, Marc P Hübner

  • Adiponectin Limits IFN-γ and IL-17 Producing CD4 T Cells in Obesity by Restraining Cell Intrinsic Glycolysis.

    Frontiers in immunology

    Authors: Jayagopi Surendar, Stefan J Frohberger, Indulekha Karunakaran, Vanessa Schmitt, Wiebke Stamminger, Anna-Lena Neumann, Christoph Wilhelm, Achim Hoerauf, Marc P Hübner

  • IL-4 receptor dependent expansion of lung CD169+ macrophages in microfilaria-driven inflammation.

    PLoS neglected tropical diseases

    Authors: Frédéric Fercoq, Estelle Remion, Stefan J Frohberger, Nathaly Vallarino-Lhermitte, Achim Hoerauf, John Le Quesne, Frédéric Landmann, Marc P Hübner, Leo M Carlin, Coralie Martin

  • In vivo kinetics of Wolbachia depletion by ABBV-4083 in L. sigmodontis adult worms and microfilariae.

    PLoS neglected tropical diseases

    Authors: Marc P Hübner, Marianne Koschel, Dominique Struever, Venelin Nikolov, Stefan J Frohberger, Alexandra Ehrens, Martina Fendler, Iliana Johannes, Thomas W von Geldern, Kennan Marsh, Joseph D Turner, Mark J Taylor, Stephen A Ward, Kenneth Pfarr, Dale J Kempf, Achim Hoerauf

  • Neural sphingosine 1-phosphate accumulation activates microglia and links impaired autophagy and inflammation.

    Glia

    Authors: Indulekha Karunakaran, Shah Alam, Surendar Jayagopi, Stefan J Frohberger, Jan N Hansen, Janina Kuehlwein, Benedikt V Hölbling, Beatrix Schumak, Marc P Hübner, Markus H Gräler, Annett Halle, Gerhild van Echten-Deckert

  • Susceptibility to L. sigmodontis infection is highest in animals lacking IL-4R/IL-5 compared to single knockouts of IL-4R, IL-5 or eosinophils.

    Parasites & vectors

    Authors: Stefan J Frohberger, Jesuthas Ajendra, Jayagopi Surendar, Wiebke Stamminger, Alexandra Ehrens, Benedikt C Buerfent, Katrin Gentil, Achim Hoerauf, Marc P Hübner

  • Discovery of short-course antiwolbachial quinazolines for elimination of filarial worm infections.

    Science translational medicine

    Authors: Malina A Bakowski, Roohollah Kazem Shiroodi, Renhe Liu, Jason Olejniczak, Baiyuan Yang, Kerstin Gagaring, Hui Guo, Pamela M White, Laura Chappell, Alain Debec, Frédéric Landmann, Bettina Dubben, Franziska Lenz, Dominique Struever, Alexandra Ehrens, Stefan J Frohberger, Hanna Sjoberg, Nicolas Pionnier, Emma Murphy, John Archer, Andrew Steven, Valerine C Chunda, Fanny F Fombad, Patrick W Chounna, Abdel J Njouendou, Haelly M Metuge, Bertrand L Ndzeshang, Narcisse V Gandjui, Desmond N Akumtoh, Tayong D B Kwenti, Ashley K Woods, Sean B Joseph, Mitchell V Hull, Wen Xiong, Kelli L Kuhen, Mark J Taylor, Samuel Wanji, Joseph D Turner, Marc P Hübner, Achim Hoerauf, Arnab K Chatterjee, Jason Roland, Matt S Tremblay, Peter G Schultz, William Sullivan, Xin-Jie Chu, H Michael Petrassi, Case W McNamara