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featured publications

  • Solubility and Stability Enhanced Oral Formulations for the Anti-Infective Corallopyronin A.

    Pharmaceutics

    Authors: Anna K Krome, Tim Becker, Stefan Kehraus, Andrea Schiefer, Christian Steinebach, Tilman Aden, Stefan J Frohberger, Álvaro López Mármol, Dnyaneshwar Kapote, Rolf Jansen, Lillibeth Chaverra-Muñoz, Marc P Hübner, Kenneth Pfarr, Thomas Hesterkamp, Marc Stadler, Michael Gütschow, Gabriele M König, Achim Hoerauf, Karl G Wagner

  • Oxfendazole mediates macrofilaricidal efficacy against the filarial nematode Litomosoides sigmodontis in vivo and inhibits Onchocerca spec. motility in vitro.

    PLoS neglected tropical diseases

    Authors: Marc P Hübner, Coralie Martin, Sabine Specht, Marianne Koschel, Bettina Dubben, Stefan J Frohberger, Alexandra Ehrens, Martina Fendler, Dominique Struever, Edward Mitre, Nathaly Vallarino-Lhermitte, Suzanne Gokool, Sara Lustigman, Manfred Schneider, Simon Townson, Achim Hoerauf, Ivan Scandale

  • Macrophages Mediate Increased CD8 T Cell Inflammation During Weight Loss in Formerly Obese Mice.

    Frontiers in endocrinology

    Authors: Jayagopi Surendar, Indulekha Karunakaran, Stefan J Frohberger, Marianne Koschel, Achim Hoerauf, Marc P Hübner

  • Top publication

    Immune Sensing of Synthetic, Bacterial, and Protozoan RNA by Toll-like Receptor 8 Requires Coordinated Processing by RNase T2 and RNase 2.

    Immunity

    Authors: Thomas Ostendorf, Thomas Zillinger, Katarzyna Andryka, Thais Marina Schlee-Guimaraes, Saskia Schmitz, Samira Marx, Kübra Bayrak, Rebecca Linke, Sarah Salgert, Julia Wegner, Tatjana Grasser, Sonja Bauersachs, Leon Soltesz, Marc P Hübner, Maximilian Nastaly, Christoph Coch, Matthias Kettwig, Ingo Roehl, Marco Henneke, Achim Hoerauf, Winfried Barchet, Jutta Gärtner, Martin Schlee, Gunther Hartmann, Eva Bartok

  • Implications of asymptomatic infection for the natural history of selected parasitic tropical diseases.

    Seminars in immunopathology

    Authors: Jorge Alvar, Fabiana Alves, Bruno Bucheton, Louise Burrows, Philippe Büscher, Eugenia Carrillo, Ingrid Felger, Marc P Hübner, Javier Moreno, Maria-Jesus Pinazo, Isabela Ribeiro, Sergio Sosa-Estani, Sabine Specht, Antoine Tarral, Nathalie Strub Wourgaft, Graeme Bilbe

  • S100A8/S100A9 deficiency increases neutrophil activation and protective immune responses against invading infective L3 larvae of the filarial nematode Litomosoides sigmodontis.

    PLoS neglected tropical diseases

    Authors: Stefan J Frohberger, Frederic Fercoq, Anna-Lena Neumann, Jayagopi Surendar, Wiebke Stamminger, Alexandra Ehrens, Indulekha Karunakaran, Estelle Remion, Thomas Vogl, Achim Hoerauf, Coralie Martin, Marc P Hübner

  • In vivo efficacy of the boron-pleuromutilin AN11251 against Wolbachia of the rodent filarial nematode Litomosoides sigmodontis.

    PLoS neglected tropical diseases

    Authors: Alexandra Ehrens, Christopher S Lunde, Robert T Jacobs, Dominique Struever, Marianne Koschel, Stefan J Frohberger, Franziska Lenz, Martina Fendler, Joseph D Turner, Stephen A Ward, Mark J Taylor, Yvonne R Freund, Rianna Stefanakis, Eric Easom, Xianfeng Li, Jacob J Plattner, Achim Hoerauf, Marc P Hübner

  • Macrofilaricidal Benzimidazole-Benzoxaborole Hybrids as an Approach to the Treatment of River Blindness: Part 1. Amide Linked Analogs.

    ACS infectious diseases

    Authors: Tsutomu Akama, Yvonne R Freund, Pamela W Berry, David S Carter, Eric E Easom, Kurt Jarnagin, Christopher S Lunde, Jacob J Plattner, Fernando Rock, Rianna Stefanakis, Chelsea Fischer, Christina A Bulman, Kee Chong Lim, Brian M Suzuki, Nancy Tricoche, Abdelmoneim Mansour, Utami DiCosty, Scott McCall, Ben Carson, John W McCall, James McKerrow, Marc P Hübner, Sabine Specht, Achim Hoerauf, Sara Lustigman, Judy A Sakanari, Robert T Jacobs

  • Short-course quinazoline drug treatments are effective in the Litomosoides sigmodontis and Brugia pahangi jird models.

    International journal for parasitology. Drugs and drug resistance

    Authors: Marc P Hübner, Emma Gunderson, Ian Vogel, Christina A Bulman, K C Lim, Marianne Koschel, Alexandra Ehrens, Stefan J Frohberger, Martina Fendler, Nancy Tricoche, Denis Voronin, Andrew Steven, Victor Chi, Malina A Bakowski, Ashley K Woods, H Michael Petrassi, Case W McNamara, Brenda Beerntsen, Laura Chappell, William Sullivan, Mark J Taylor, Joseph D Turner, Achim Hoerauf, Sara Lustigman, Judy A Sakanari

  • Protection of Batf3-deficient mice from experimental cerebral malaria correlates with impaired cytotoxic T-cell responses and immune regulation.

    Immunology

    Authors: Janina M Kuehlwein, Max Borsche, Patricia J Korir, Frederic Risch, Ann-Kristin Mueller, Marc P Hübner, Kai Hildner, Achim Hoerauf, Ildiko Rita Dunay, Beatrix Schumak