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  • The protein kinase DYRK1B is a p53 target gene and functions as a negative feedback regulator of the transcription factor RFX7.

    Cell death & disease

    Authors: Gerrit Wilms, Katharina Schwandt, Stefan Düsterhöft, Philip Helmich, Justyna Wozniak, Florian Kraft, Sebastian Kallabis, Felix Meissner, Walter Becker

  • Blocking microglial reactivity via purinergic receptors prevents subacute cognitive deficits after TIA.

    EMBO molecular medicine

    Authors: Gemma Llovera, Steffanie Heindl, Daniel P Varga, Nikolett Lenart, Sebastian Kallabis, Vanessa Göb, David Stegner, Raphael Escaig, Leo Nicolai, Nicolai Franzmeier, Felix Meissner, Adam Denes, Arthur Liesz

  • Endothelial ADGRF5(GPR116) governs vascular adaptation required for sustained thermogenic remodeling of brown adipose tissue.

    Molecular metabolism

    Authors: Rabih El-Merahbi, Vasiliki Karagiannakou, Ronja Kardinal, Lea Seep, Richard Lindner, Michelle Ynonne Jäckstein, Staffan Hildebrand, Mersiha Hasic, Eylül Korkmaz, Ankush Kumar Jha, Aspasia Thodou Krokidi, Kenneth Dyar, Felix Meissner, Stephan Grein, Jörg Heeren, Martin Klingenspor, Alexander Pfeifer, Jan Hasenauer, Dagmar Wachten, Stephan Herzig, Anastasia Georgiadi

  • Cytohesin-2 is essential for the perinatal development of mice and regulates Golgi volume.

    Life science alliance

    Authors: Carsten Küsters, Bettina Jux, Farhad Shakeri, Sebastian Kallabis, Felix Meissner, Waldemar Kolanus

  • Poxvirus dsDNA genomes differentially activate AIM2 or NLRP3 inflammasomes in human primary cells.

    The EMBO journal

    Authors: Yonas M Tesfamariam, Maria H Christensen, Stefan Diehl, Tabea Klein, Julius M Lingnau, Sabine Normann, Elena Hagelauer, Miriam Herbert, Sophie Reimer, Richa P Joshi, Pujan Engels, Steffen Pritzl, Pietro Fontana, Thomas Zillinger, Gunther Hartmann, Anna Eis-Hübinger, Martin C Lam, Klaus J Walgenbach, Felix Meissner, Hao Wu, Florian I Schmidt

  • A centrally positioned cluster of multiple centrioles in antigen-presenting cells fosters T cell activation.

    Nature communications

    Authors: Isabel Stötzel, Ann-Kathrin Weier, Apurba Sarkar, Subhendu Som, Luisa Bach, Peter Konopka, Eliška Miková, Shaunak Ghosh, Jan Böthling, Mirka Homrich, Laura Schaedel, Uli Kazmaier, Konstantinos Symeonidis, Stefan Ebner, Philip Weidner, Zeinab Abdullah, Felix Meissner, Stefan Uderhardt, Miroslav Hons, Dirk Baumjohann, Raja Paul, Heiko Rieger, Eva Kiermaier

  • Mutations in VPS18 lead to a neutrophil maturation defect associated with disturbed vesicle homeostasis.

    Cell death & disease

    Authors: Jincheng Gao, Almke Bader, Monika I Linder, Jingyuan Cheng, Mathis Richter, Raul da Costa, Annette Zehrer, Karl Mitt, Bastian Popper, Felix Meissner, Xiang Wei, Enrique de Vega Gómez, Megumi Tatematsu, Meino Rohlfs, Stephanie Frenz-Wiessner, Mehmet Kiziltug, Ido Somekh, Joanne Yacobovich, Orna Steinberg-Shemer, Raz Somech, Oliver Soehnlein, Bettina Schmid, Christoph Klein, Barbara Walzog, Daniela Maier-Begandt

  • Kupffer cells control neonatal hepatic metabolism via Igf1 signaling.

    Development (Cambridge, England)

    Authors: Nikola Makdissi, Daria Hirschmann, Aleksej Frolov, Inaam Sado, Bastian Bennühr, Fabian Nikolka, Jingyuan Cheng, Nelli Blank-Stein, Maria Francesca Viola, Mohamed Yaghmour, Philipp Arnold, Lorenzo Bonaguro, Matthias Becker, Christoph Thiele, Felix Meissner, Karsten Hiller, Marc D Beyer, Elvira Mass

  • Lymphoid gene expression supports neuroprotective microglia function.

    Nature

    Authors: Pinar Ayata, Jessica M Crowley, Matthew F Challman, Vinaya Sahasrabuddhe, Maud Gratuze, Sebastian Werneburg, Diogo Ribeiro, Emma C Hays, Violeta Durán-Laforet, Travis E Faust, Philip Hwang, Francisco Mendes Lopes, Chrysa Nikopoulou, Sarah Buchholz, Robert E Murphy, Taoyu Mei, Anna A Pimenova, Carmen Romero-Molina, Francesca Garretti, Tulsi A Patel, Claudia De Sanctis, Angie V Ramirez Jimenez, Megan Crow, Felix D Weiss, Jason D Ulrich, Edoardo Marcora, John W Murray, Felix Meissner, Andreas Beyer, Dan Hasson, John F Crary, Dorothy P Schafer, David M Holtzman, Alison M Goate, Alexander Tarakhovsky, Anne Schaefer

  • Mass spectrometry-based peripheral blood proteomics for biomarker discovery in idiopathic pulmonary fibrosis.

    Respiratory research

    Authors: Aravind A Menon, Benedikt Gansen, Hillary Mulder, Megan L Neely, Panagiotis Papavasileiou, Margaret L Salisbury, Brian D Southern, Christian Hesslinger, Thomas B Leonard, Felix Meissner, Jamie L Todd