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  • A TLR4-dependent fibroblast-monocyte axis in tumor-draining lymph nodes contributes to metastasis in triple-negative breast cancer.

    Immunity

    Authors: Greta Mattavelli, Moutaz Helal, Ana Cetkovic, Maximilian J Krämer, Saskia-Laureen Herbert, Kilian Mielert, Tanja Schlaiß, Anna Frank, Emily Riemer, Mara John, Josefina Del Pilar, Martinez Vasquez, Laura Kindl, Jonathan J Swietlik, Benedikt O Gansen, Marion Krafft, Emilia Stanojkovska, Hanna Fischer, Ute-Susann Albert, Jonas Bauer, Murilo Delgobo, Arpa Aintablian, Haisam Alattar, Manfred B Lutz, Felix Meissner, Thordur Oskarsson, Leo Rasche, Gustavo Ramos, Andreas Rosenwald, Achim Wöckel, Angela Riedel

  • Global matrisome changes in obese lung are linked to fibroblastic stroma and premature aging.

    Cell reports

    Authors: Sophia Rottmann, Jian Li, Jelena Zurkovic, Pablo S Bravo, Andreas U Lindner, Jie Qin, Sebastian Kallabis, Qi Mei, Xiansheng Liu, Christoph Thiele, Christoph Eckert, Felix Meissner, Veronika Lukacs-Kornek

  • Discovery and Functional Characterization of a Potent, Selective, and Metabolically Stable PROTAC of the Protein Kinases DYRK1A and DYRK1B.

    Journal of medicinal chemistry

    Authors: Gerrit Wilms, Kevin Schofield, Shayna Maddern, Christopher Foley, Yeng Shaw, Breland Smith, L Emilia Basantes, Katharina Schwandt, Aaron Babendreyer, Timothy Chavez, Nicholas McKee, Vijay Gokhale, Sebastian Kallabis, Felix Meissner, Samantha N Rokey, Travis Dunckley, William R Montfort, Walter Becker, Christopher Hulme

  • Retention of ES cell-derived 129S genome drives NLRP1 hypersensitivity and transcriptional deregulation in Nlrp3 mice.

    Cell death and differentiation

    Authors: Felix D Weiss, Yubell Alvarez, Farhad Shakeri, Anshupa Sahu, Petro Leka, Alesja Dernst, Jessika Rollheiser, Matilde Vasconcelos, Adriana Geraci, Fraser Duthie, Rainer Stahl, Hye Eun Lee, Anne-Kathrin Gellner, Andreas Buness, Eicke Latz, Felix Meissner

  • Butyrate and propionate are microbial danger signals that activate the NLRP3 inflammasome in human macrophages upon TLR stimulation.

    Cell reports

    Authors: Wei Wang, Alesja Dernst, Bianca Martin, Lucia Lorenzi, Maria Cadefau-Fabregat, Kshiti Phulphagar, Antonia Wagener, Christina Budden, Neil Stair, Theresa Wagner, Harald Färber, Andreas Jaensch, Rainer Stahl, Fraser Duthie, Susanne V Schmidt, Rebecca C Coll, Felix Meissner, Sergi Cuartero, Eicke Latz, Matthew S J Mangan

  • Platelet transcription factors license the pro-inflammatory cytokine response of human monocytes.

    EMBO molecular medicine

    Authors: Ibrahim Hawwari, Lukas Rossnagel, Nathalia Rosero, Salie Maasewerd, Matilde B Vasconcelos, Marius Jentzsch, Agnieszka Demczuk, Lino L Teichmann, Lisa Meffert, Damien Bertheloot, Lucas S Ribeiro, Sebastian Kallabis, Felix Meissner, Moshe Arditi, Asli E Atici, Magali Noval Rivas, Bernardo S Franklin

  • Author Correction: Gel-like inclusions of C-terminal fragments of TDP-43 sequester stalled proteasomes in neurons.

    EMBO reports

    Authors: Henrick Riemenschneider, Qiang Guo, Jakob Bader, Frédéric Frottin, Daniel Farny, Gernot Kleinberger, Christian Haass, Matthias Mann, F Ulrich Hartl, Wolfgang Baumeister, Mark S Hipp, Felix Meissner, Rubén Fernández-Busnadiego, Dieter Edbauer

  • Top publication

    From Planning Stage Towards FAIR Data: A Practical Metadatasheet For Biomedical Scientists.

    Scientific data

    Authors: Lea Seep, Stephan Grein, Iva Splichalova, Danli Ran, Mickel Mikhael, Staffan Hildebrand, Mario Lauterbach, Karsten Hiller, Dalila Juliana Silva Ribeiro, Katharina Sieckmann, Ronja Kardinal, Hao Huang, Jiangyan Yu, Sebastian Kallabis, Janina Behrens, Andreas Till, Viktoriya Peeva, Akim Strohmeyer, Johanna Bruder, Tobias Blum, Ana Soriano-Arroquia, Dominik Tischer, Katharina Kuellmer, Yuanfang Li, Marc Beyer, Anne-Kathrin Gellner, Tobias Fromme, Henning Wackerhage, Martin Klingenspor, Wiebke K Fenske, Ludger Scheja, Felix Meissner, Andreas Schlitzer, Elvira Mass, Dagmar Wachten, Eicke Latz, Alexander Pfeifer, Jan Hasenauer

  • Top publication

    TGF-β specifies T versus T17 cell fates in murine CD4 T cells through c-Maf.

    Science immunology

    Authors: Yinshui Chang, Luisa Bach, Marko Hasiuk, Lifen Wen, Tarek Elmzzahi, Carlson Tsui, Nicolás Gutiérrez-Melo, Teresa Steffen, Daniel T Utzschneider, Timsse Raj, Paul Jonas Jost, Sylvia Heink, Jingyuan Cheng, Oliver T Burton, Julia Zeiträg, Dominik Alterauge, Frank Dahlström, Jennifer-Christin Becker, Melanie Kastl, Konstantinos Symeonidis, Martina van Uelft, Matthias Becker, Sarah Reschke, Stefan Krebs, Helmut Blum, Zeinab Abdullah, Katrin Paeschke, Caspar Ohnmacht, Christian Neumann, Adrian Liston, Felix Meissner, Thomas Korn, Jan Hasenauer, Vigo Heissmeyer, Marc Beyer, Axel Kallies, Lukas T Jeker, Dirk Baumjohann

  • Landscape of protein-protein interactions during hepatitis C virus assembly and release.

    Microbiology spectrum

    Authors: Alina Matthaei, Sebastian Joecks, Annika Frauenstein, Janina Bruening, Dorothea Bankwitz, Martina Friesland, Gisa Gerold, Gabrielle Vieyres, Lars Kaderali, Felix Meissner, Thomas Pietschmann