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  • Mutations in VPS18 lead to a neutrophil maturation defect associated with disturbed vesicle homeostasis.

    Cell death & disease

    Authors: Jincheng Gao, Almke Bader, Monika I Linder, Jingyuan Cheng, Mathis Richter, Raul da Costa, Annette Zehrer, Karl Mitt, Bastian Popper, Felix Meissner, Xiang Wei, Enrique de Vega Gómez, Megumi Tatematsu, Meino Rohlfs, Stephanie Frenz-Wiessner, Mehmet Kiziltug, Ido Somekh, Joanne Yacobovich, Orna Steinberg-Shemer, Raz Somech, Oliver Soehnlein, Bettina Schmid, Christoph Klein, Barbara Walzog, Daniela Maier-Begandt

  • Kupffer cells control neonatal hepatic metabolism via Igf1 signaling.

    Development (Cambridge, England)

    Authors: Nikola Makdissi, Daria Hirschmann, Aleksej Frolov, Inaam Sado, Bastian Bennühr, Fabian Nikolka, Jingyuan Cheng, Nelli Blank-Stein, Maria Francesca Viola, Mohamed Yaghmour, Philipp Arnold, Lorenzo Bonaguro, Matthias Becker, Christoph Thiele, Felix Meissner, Karsten Hiller, Marc D Beyer, Elvira Mass

  • Lymphoid gene expression supports neuroprotective microglia function.

    Nature

    Authors: Pinar Ayata, Jessica M Crowley, Matthew F Challman, Vinaya Sahasrabuddhe, Maud Gratuze, Sebastian Werneburg, Diogo Ribeiro, Emma C Hays, Violeta Durán-Laforet, Travis E Faust, Philip Hwang, Francisco Mendes Lopes, Chrysa Nikopoulou, Sarah Buchholz, Robert E Murphy, Taoyu Mei, Anna A Pimenova, Carmen Romero-Molina, Francesca Garretti, Tulsi A Patel, Claudia De Sanctis, Angie V Ramirez Jimenez, Megan Crow, Felix D Weiss, Jason D Ulrich, Edoardo Marcora, John W Murray, Felix Meissner, Andreas Beyer, Dan Hasson, John F Crary, Dorothy P Schafer, David M Holtzman, Alison M Goate, Alexander Tarakhovsky, Anne Schaefer

  • Mass spectrometry-based peripheral blood proteomics for biomarker discovery in idiopathic pulmonary fibrosis.

    Respiratory research

    Authors: Aravind A Menon, Benedikt Gansen, Hillary Mulder, Megan L Neely, Panagiotis Papavasileiou, Margaret L Salisbury, Brian D Southern, Christian Hesslinger, Thomas B Leonard, Felix Meissner, Jamie L Todd

  • A TLR4-dependent fibroblast-monocyte axis in tumor-draining lymph nodes contributes to metastasis in triple-negative breast cancer.

    Immunity

    Authors: Greta Mattavelli, Moutaz Helal, Ana Cetkovic, Maximilian J Krämer, Saskia-Laureen Herbert, Kilian Mielert, Tanja Schlaiß, Anna Frank, Emily Riemer, Mara John, Josefina Del Pilar, Martinez Vasquez, Laura Kindl, Jonathan J Swietlik, Benedikt O Gansen, Marion Krafft, Emilia Stanojkovska, Hanna Fischer, Ute-Susann Albert, Jonas Bauer, Murilo Delgobo, Arpa Aintablian, Haisam Alattar, Manfred B Lutz, Felix Meissner, Thordur Oskarsson, Leo Rasche, Gustavo Ramos, Andreas Rosenwald, Achim Wöckel, Angela Riedel

  • Global matrisome changes in obese lung are linked to fibroblastic stroma and premature aging.

    Cell reports

    Authors: Sophia Rottmann, Jian Li, Jelena Zurkovic, Pablo S Bravo, Andreas U Lindner, Jie Qin, Sebastian Kallabis, Qi Mei, Xiansheng Liu, Christoph Thiele, Christoph Eckert, Felix Meissner, Veronika Lukacs-Kornek

  • Discovery and Functional Characterization of a Potent, Selective, and Metabolically Stable PROTAC of the Protein Kinases DYRK1A and DYRK1B.

    Journal of medicinal chemistry

    Authors: Gerrit Wilms, Kevin Schofield, Shayna Maddern, Christopher Foley, Yeng Shaw, Breland Smith, L Emilia Basantes, Katharina Schwandt, Aaron Babendreyer, Timothy Chavez, Nicholas McKee, Vijay Gokhale, Sebastian Kallabis, Felix Meissner, Samantha N Rokey, Travis Dunckley, William R Montfort, Walter Becker, Christopher Hulme

  • Retention of ES cell-derived 129S genome drives NLRP1 hypersensitivity and transcriptional deregulation in Nlrp3 mice.

    Cell death and differentiation

    Authors: Felix D Weiss, Yubell Alvarez, Farhad Shakeri, Anshupa Sahu, Petro Leka, Alesja Dernst, Jessika Rollheiser, Matilde Vasconcelos, Adriana Geraci, Fraser Duthie, Rainer Stahl, Hye Eun Lee, Anne-Kathrin Gellner, Andreas Buness, Eicke Latz, Felix Meissner

  • Butyrate and propionate are microbial danger signals that activate the NLRP3 inflammasome in human macrophages upon TLR stimulation.

    Cell reports

    Authors: Wei Wang, Alesja Dernst, Bianca Martin, Lucia Lorenzi, Maria Cadefau-Fabregat, Kshiti Phulphagar, Antonia Wagener, Christina Budden, Neil Stair, Theresa Wagner, Harald Färber, Andreas Jaensch, Rainer Stahl, Fraser Duthie, Susanne V Schmidt, Rebecca C Coll, Felix Meissner, Sergi Cuartero, Eicke Latz, Matthew S J Mangan

  • MetRS*-based deep cell-selective tissue proteomics and secretomics in vivo.

    Methods in cell biology

    Authors: Jonathan J Swietlik, Felix Meissner