—Molecular switch in bone marrow stem cells helps research into inflammatory processes in the brain.
Macrophages are part of the innate immune system and essential for brain development and function. Using a novel method, scientists from Jena University Hospital, the Cluster of Excellence ImmunoSensation and the Memorial Sloan Kettering Cancer Center in New York (USA) succeeded in visualizing macrophages that were formed in the bone marrow.
—The EU-Research Projekt ImmunoSep starts and members of the Cluster of Excellence ImmunoSensation Mihai Netea and Joachim L. Schultze are part of the research consortium led by the Radboud University Medical Center, Nijmegen, Netherlands.
Within the next 4 years more then 10 Million Euro are provided by the EU-wide Horizon2020 program and the University of Bonn will receive around 750.000 Euro.
—Prof. Dr. Christian Kurts, Professor of Experimental Immunology at the University of Bonn, has been appointed honorary professor at the Department of Microbiology and Immunology at the University of Melbourne. With this appointment, Australia's leading university acknowledges the achievements in establishing a scientific network between Melbourne and Bonn.
Gunther Hartmann appointed member of the Henry Kunkel Society
—The Henry Kunkel Society (HKS) is a prestigious organization dedicated to fostering patient-based and patient-oriented scientific research, particularly in the field of immunology, as exemplified by the scientific life of Dr. Henry Kunkel at the Rockefeller University. Originally founded in 1990 and comprising of only 50 members at that time, most of whom were former trainees of Henry Kunkel, the Society has grown to include over 400 elected members, all dedicated to experimental medicine in the field of human immunology.
—Researchers at the German Center for Neurodegenerative Diseases (DZNE) and the University of Bonn have now shown this in a proof-of-concept study. Their approach is based on the analysis of the gene activity of cells found in the blood. Used in practice, this approach could support conventional diagnostics and possibly accelerate the beginning of therapy.
—Macrophages have two faces: In healthy tissue, they perform important tasks and support their environment. However during an infection, they stop this work and hunt down the pathogens instead. Upon coming into contact with bacteria they change their metabolism drastically within minutes.
—Annually the 'Highly Cited Researchers' are being announced by the 'Web of Science Group'.
At the University of Bonn 12 highly cited researcher are namend, among them are 6 members of the cluster of excellence ImmunoSensation.
—Inflammatory Processes Drive Progression of Alzheimer's and Other Brain Diseases.
Report in "Nature Inflammation" drives the progression of neurodegenerative brain diseases and plays a major role in the accumulation of tau proteins within neurons. An international research team led by Prof. Michael Heneka (DZNE), member of cluster of excellence ImmunoSensation, and the University of Bonn comes to this conclusion in the journal "Nature"
