—Inflammatory Processes Drive Progression of Alzheimer's and Other Brain Diseases.
Report in "Nature" Inflammation drives the progression of neurodegenerative brain diseases and plays a major role in the accumulation of tau proteins within neurons. An international research team led by Prof. Michael Heneka (DZNE), member of cluster of excellence ImmunoSensation, and the University of Bonn comes to this conclusion in the journal "Nature".
—Thanks for all the participants who attended this years Cluster Science Days. More than 300 participants, 105 poster and lots of red wine during the scientific pub quiz made the Cluster Science Days 2019 memorable.
—Cluster Member Prof. Nickenig and an international team of physicians published a recent study about the minimal invasive treatment of tricuspid regurgitation in the Journal 'Lancet'.
—Aggressive forms of breast cancer often manipulate the immune response in their favor. This manipulation is revealed in humans by the same immunological "signature" as in mice. This is shown by a study carried out by scientists from the University of Bonn and memebers of the Cluster of Excellence ImmunoSensation together with Dutch colleagues. Their method makes it possible to obtain an indication of the prognosis of the disease using patients' tumor tissue.
—A high-profile delegation of the University of Melbourne visited the University of Bonn in order to discuss a closer cooperation in research and training of early-career researchers. The Australian university is one of three strategic partnerships the University of Bonn maintains. Close links already exist especially in the areas of Food and Nutrition Sciences and Agricultural Sciences.
The Australian delegation of five was led by Vice-Chancellor Prof. Duncan Maskell. The position of Vice-Chancellor is equivalent to the position of a Rector in the German higher education system. Prof.…
—Without fat, nothing works in the body: These substances serve as energy suppliers and important building blocks - including for the envelopes of living cells. Numerous diseases are related to disorders in the fat metabolism, such as obesity or cancer. Prof. Christoph Thiele from the LIMES Institute at the University of Bonn and member of the Cluster of Excellence ImmunoSensation and others are now demonstrating how the fat metabolism can be monitored down to the individual liver cell of a mouse with the greatest sensitivity. This opens up several possibilities, such as minimizing the side…
—In some forms of epilepsy, the function of certain "brake cells" in the brain is presumed to be disrupted. This may be one of the reasons why the electrical malfunction is able to spread from the point of origin across large parts of the brain. A current study by the University of Bonn with members of the cluster of excellence ImmunoSensation, in which researchers from Lisbon were also involved, points in this direction. The results are published in the Journal of Neuroscience.
—Dr. Elvira Mass from the LIMES Institute and member of the Cluster of Excellence ImmunoSensation of the University of Bonn receives a coveted Starting Grant from the European Research Council (ERC). This will mean a subsidy of 1.5 million euros over the next five years.
—More than 21 million people in Africa are infected with the nematode Onchocerca volvulus, the cause of river blindness. Around one in ten of those affected goes blind. Parasitologists around Prof. Hörauf at the University Hospital Bonn are looking for new, more effective weapons against the insidious parasite.
