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featured publications

  • Integrating C-reactive protein flare and early MRI dynamics for enhanced prediction of immunotherapy response.

    Journal for immunotherapy of cancer

    Authors: Daniel Navarro-Garcia, Francesco Grussu, Christina Zatse, Niklas Klümper, Carlos Macarro, Alberto Hernando-Calvo, Marta Sanz, Maria Vieito, Irene Braña, Oriol Mirallas, Guzmán Alonso, Vladimir Galvao, Giulia Pretelli, Julia Lostes, Arjun Oberoi, Rodrigo Toledo, Paolo Nuciforo, Elena Garralda, Raquel Perez-Lopez

  • High-salt diet induces immune-independent re-differentiation, metabolic shut down and cell cycle arrest of melanoma.

    Cell death & disease

    Authors: Clivia Lisowski, Natascha E Stumpf, Katarzyna Jobin, Daniela Klaus, Melanie Eichler, Ann-Kathrin Baumgart, Olena Babyak, Mirjam Meißner, Agnes Schröder, Patrick Neubert, Vanessa Schmitt, Marcel Michla, Süleyman Bozkurt, Jelena Zurkovic, Daniel Hinze, Jana Liebing, Matthias Eckhardt, Christoph Heuser, Lea Seep, Annkristin Heine, Janine Becker-Gotot, Christoph Thiele, Christian Münch, Thomas Becker, Jonathan Jantsch, Christoph Wilhelm, Michael Hölzel, Christian Kurts

  • Genomic and transcriptomic analyses of aortic stenosis enhance therapeutic target discovery and disease prediction.

    Nature genetics

    Authors: Aeron M Small, Ta-Yu Yang, Shinsuke Itoh, Sébastien Thériault, Line Dufresne, Ryo Kurosawa, Issei Komuro, Koichi Matsuda, Ha My T Vy, Eric H Farber-Eger, Lauren Lee Shaffer, Kristin M Boulier, Kristin M Corey, Megan E Ramaker, Fabien Laporte, Jean-Jacques Schott, Solena Le Scouarnec, Sasha A Singh, Abhijeet R Sonawane, Harry A Smith, Nicholas Rafaels, Jonas Ghouse, Anna A Raja, Sisse R Ostrowski, Erik Sørensen, Christina Mikkelsen, Ole B Pedersen, Christian Erikstrup, Henrik Ullum, Gardar Sveinbjornsson, Daniel F Gudbjartsson, Erik Abner, Jiwoo Lee, Andrea Ganna, Ulrike Nowak-Göttl, Sarah Finer, Johannes Schumacher, Carlo Maj, Baravan Al-Kassou, Georg Nickenig, Teresa Trenkwalder, Martina Dreβen, Markus Krane, Markus M Nöthen, Marta R Moksnes, Ben M Brumpton, Stacey Knight, Kirk U Knowlton, Lincoln Nadauld, Radek Debiec, Muntaser D Musameh, Peter S Braund, Christopher P Nelson, Tomasz Czuba, Olle Melander, Margaret Sunitha Selvaraj, Satoshi Koyama, Rohan Bhukar, Yunfeng Ruan, Johan Ljungberg, Scott M Damrauer, Michael G Levin, Andre Franke, Klaus Berger, Christian T Ruff, Giorgio E M Melloni, Frederick K Kamanu, Kaoru Ito, Ron Do, Ruth J F Loos, Heribert Schunkert, Quinn S Wells, Svati H Shah, Thierry Le Tourneau, David Messika-Zeitoun, Christopher Gignoux, Henning Bundgaard, Susanna C Larsson, Karl Michaëlsson, Hilma Holm, Anna Helgadottir, Tonu Esko, David A van Heel, Patrick Mathieu, Nilesh J Samani, J Gustav Smith, Stefan Söderberg, Daniel J Rader, Nicholas A Marston, Marc S Sabatine, Bogdan Pasaniuc, Kelly Cho, Peter W F Wilson, Christopher J O'Donnell, Kari Stefansson, Yohan Bossé, Elena Aikawa, James C Engert, Gina M Peloso, Pradeep Natarajan, George Thanassoulis

  • Longitudinal Monitoring of Brain Volume Changes After COVID-19 Infection Using Artificial Intelligence-Based MRI Volumetry.

    Diagnostics (Basel, Switzerland)

    Authors: Zeynep Bendella, Catherine Nichols Widmann, Christine Kindler, Robert Haase, Malte Sauer, Michael T Heneka, Alexander Radbruch, Frederic Carsten Schmeel

  • Targeting the tumor cell-intrinsic ITGB2 axis inhibits melanoma progression.

    Molecular cancer

    Authors: Erik Rasbach, Laure Migayron, Anne Brandenburg, Praveen Singh, Christina Martins, Ali Kassem, Anastasia I Karkempetzaki, Nadine Suessner, Zsofi Kulcsar, Jessica Riopedre, Mariana Silva, Ethan Zhen, Shuyun Xu, Kyla Mucciarone, Julia Holzgruber, Jason B Williams, Emrullah Birgin, Mitchell P Levesque, Julia M Martínez-Gómez, Reinhard Dummer, Jennifer Landsberg, Christine G Lian, George F Murphy, Emma L Berdan, Shannan Ho Sui, Thomas S Kupper, Nuh N Rahbari, Nayoung Lee, Steven R Barthel, Tobias Schatton

  • TALON phase IIIb study: 64 week results of brolucizumab versus aflibercept using treat-and-extend for neovascular age-related macular degeneration.

    Eye (London, England)

    Authors: Carl Regillo, Peter K Kaiser, Peter J Kertes, Mark Gillies, Tina Maio-Twofoot, David Lawrence, Frank G Holz

  • Serum-free differentiation platform for the generation of B lymphocytes and natural killer cells from human CD34+ cord blood progenitors.

    Scientific reports

    Authors: Rigveda Bhave, Carla-Johanna Kath, Nadine Rüchel, Eleni Vasileiou, Vera H Jepsen, Katharina Raba, Aleksandra A Pandyra, Ute Fischer, Gesine Kogler

  • Patient-Derived Monoclonal Myelin Oligodendrocyte Glycoprotein Autoantibodies Mediate Cytotoxicity.

    Neurology(R) neuroimmunology & neuroinflammation

    Authors: Nora Sandrine Wetzel, Laila Kulsvehagen, Anne-Catherine Lecourt, Beata Filipek, Patrick Lipps, Laura Rieder, Kristina Berve, Gurumoorthy Krishnamoorthy, Bert A 't Hart, Lucas Schirmer, Soumya S Yandamuri, Kevin C O'Connor, Anne-Katrin Pröbstel

  • Myeloperoxidase aggravates thoracic aortic aneurysm formation in Marfan disease.

    Cardiovascular research

    Authors: Dennis Mehrkens, Johannes Dohr, Felix Sebastian Nettersheim, Felix Ballmann, Jil Bastigkeit, Alexander Brückner, Simon Geissen, Lauren De Vore, Cedric Fitsch, Chris Diekmann, Andrea de la Fuente-Alonso, Patrik Schelemei, Felix Ruben Picard, Malte Kochen, Per Arkenberg, Anna Rappenecker, Maysam Ahdab, Harshal Nemade, Suchitra Narayan, Simon Braumann, Wiebke Kreuzberg, Alexander Hof, Henning Guthoff, Benedicta Quaye Mensah, Sebastian Lechner, Andrea Guala, Artur Evangelista, Gisela Teixido-Tura, J Francisco Nistal, Miguel R Campanero, Harald Kaemmerer, Zsuzsanna Wolf, Stefan Holdenrieder, Maarten Groenink, Mitzi van Andel, Arnout Mieremet, Susanne Pfeiler, Norbert Gerdes, Ulrich Flögel, Laura-Maria Zimmermann, Gerhard Sengle, Marie-Lisa Eich, Birgid Schömig-Markiefka, Matti Adam, Bernd K Fleischmann, Daniela Wenzel, Juan Miguel Redondo, Vivian de Waard, Anna Klinke, Stephan Baldus, Martin Mollenhauer, Holger Winkels

  • TMEM65-dependent Ca2+ extrusion safeguards mitochondrial homeostasis.

    Nature communications

    Authors: Massimo Vetralla, Lena Wischhof, Asrat Kahsay, Vanessa Cadenelli, Enzo Scifo, Beijia Xie, Miriana Sbrissa, Maëlle Sandhira Habert, Dan Ehninger, Rosario Rizzuto, Daniele Bano, Diego De Stefani