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  • Frequent and clinically relevant germline DNA repair gene variants in young and familial myeloproliferative neoplasms.

    Blood cancer journal

    Authors: Robert Meyer, Maria Jimena Rodriguez, Madeline Caduc, Kim Kricheldorf, Matthias Begemann, Florian Kraft, Isabel Spier, Daniela Dey, Nergis Güzel, Kerstin Becker, Julian Baumeister, Marcelo A S de Toledo, Susanne Isfort, Ulrich Germing, Stefan Aretz, Tim H Brümmendorf, Ingo Kurth, Miriam Elbracht, Lino L Teichmann, Steffen Koschmieder

  • Phase 3 study of intensive chemotherapy with or without dasatinib in core-binding factor acute myeloid leukemia.

    Blood

    Authors: Hartmut Döhner, Daniela Späth, Maral Saadati, Walter Fiedler, Katharina S Götze, Elisabeth Koller, Jörg Westermann, Wichard Vogel, Michael Heuser, Michael Lübbert, Hans-Joachim Tischler, Ulrich Germing, Lino Lars Teichmann, Lars Fransecky, Albert Wölfler, David Nachbaur, Bernd Hertenstein, Roland Schroers, Uwe M Martens, Stephanie von Harsdorf, Markus P Radsak, Gregor Aschauer, Stefanie Weißhaar, Andrea Corbacioglu, Anika Schrade, Verena I Gaidzik, Felicitas R Thol, Peter Paschka, Lars Bullinger, Axel Benner, Konstanze Döhner, Arnold Ganser

  • Integrating simulated and experimental data to identify mitochondrial bioenergetic defects in Parkinson's Disease models.

    PloS one

    Authors: Sandeep Chenna, Alvin Joselin, Pierre Theurey, Daniele Bano, Paola Pizzo, Maria Ankarcrona, David S Park, Jochen H Prehn, Niamh M C Connolly

  • Effects of lipopolysaccharide on energy metabolism and immune cell activation in different microglia model systems.

    Brain, behavior, and immunity

    Authors: Susanne Michels, Johanna Eichberg, Fahd Alhamdan, Micha Engeser, Rafael Leite Dantas, Felix Sr Picard, Mona Mathews-Ajendra, Oliver Brüstle, Martin K-H Schäfer, Judith Alferink, Holger Garn, Markus Wöhr, Carsten Culmsee

  • Temporal dynamics of SARS-CoV-2 antibodies and IgG subclasses following multiple doses and diverse COVID-19 vaccine combinations.

    Frontiers in immunology

    Authors: Julia Meyer, Achim Hoerauf, Aleksandra Elzbieta Dubiel, Peđa Kovačević, Anika Trudić, Dragan Primorac, Marc P Hübner, Tomabu Adjobimey, Marijo Parcina

  • Discovery of Histone Deacetylase 8-Specific Proteolysis-Targeting Chimeras with Anticancer Activity against Hematological Malignancies.

    Journal of medicinal chemistry

    Authors: Shiyang Zhai, Marie Kemkes, Cindy-Esther Kponomaizoun, Jan Gerhartz, Felix Feller, Jia-Wey Tu, Dominika Ewa Pieńkowska, Julian Schliehe-Diecks, Ina Dressel, Michael Gütschow, Radosław P Nowak, Christian Steinebach, Sanil Bhatia, Finn K Hansen

  • Lymphotoxin-dependent elevated meningeal CXCL13:BAFF ratios drive gray matter injury.

    Nature immunology

    Authors: Ikbel Naouar, Andrei Pangan, Michelle Zuo, Syed Ali Raza, Kevin Champagne-Jorgensen, Jyot Patel, Angela Wang, Annie Pu, Lesley Ward, Jennifer S Y Ahn, Faizah N Sayeed, Jingwen Zhu, Elisabeth Pössnecker, Shoshana Spring, John G Sled, Bruno Cenni, Barbara Nuesslein-Hildesheim, Jeffrey L Browning, Anne-Katrin Pröbstel, Daniel S Reich, Jennifer L Gommerman, Valeria Ramaglia

  • A randomized controlled trial of precision bezlotoxumab treatment for Clostridioides difficile infection.

    Cell reports. Medicine

    Authors: Christos Psarrakis, Nikolaos-Renatos Tziolos, Vicky Matzarakis, Vinod Kumar, Emmanouil Stylianakis, Chrysanthi Sidiropoulou, Elisavet Tasouli, Konstantina Iliopoulou, Michael Samarkos, Symeon Metallidis, Sarah Georgiadou, Karolina Akinosoglou, Amalia Bolanou, Erifli Hatziagelaki, Alina Kostaki, Periklis Panagopoulos, Konstantinos Toutouzas, Haralarampos Milionis, Georgios Adamis, Garyfallia Poulakou, Malvina Lada, Athanasios Skoutelis, Zoi Alexiou, Styliani Symbardi, George Chrysos, Mihai G Netea, Evangelos J Giamarellos-Bourboulis

  • Systemically inducing trained immunity overcomes solid tumors' immunosuppressive microenvironment.

    Science advances

    Authors: Bram Priem, Lisa Willemsen, Tom Anbergen, Yuri van Elsas, Jeroen Deckers, David P Schrijver, Stijn R J Hofstraat, Iris V Messing, Jazz Munitz, Dionne Honing, Geoffrey Prévot, Yohana C Toner, Judit Morla, William Wang, Anna Ranzenigo, Isabella Sirchia, Tomas Post, Raphaël Duivenvoorden, Ewelina Kluza, Glenn A O Cremers, Joost H C M Kreijtz, Carlos Pérez-Medina, Mandy M T van Leent, Abraham J P Teunissen, Roy van der Meel, Yi Zhou, Chris Glass, Jordi Ochando, Leo A B Joosten, Zahi A Fayad, Romana T Netea-Maier, Mihai G Netea, Menno P J de Winther, Thijs J Beldman, Arjan W Griffioen, Willem J M Mulder

  • Immunotherapies in progressive multiple sclerosis.

    Handbook of clinical neurology

    Authors: Tradite Neziraj, Ludwig Kappos, Anne-Katrin Pröbstel