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  • Bicuspid aortic valve stenosis is characterized by increased angiogenesis, inflammation, and a higher valvular-to-systemic calcification ratio than tricuspid aortic valve stenosis.

    Basic research in cardiology

    Authors: Alexander Brückner, Adrian Brandtner, Sarah Rieck, Hannah Billig, Werner Masson, Anna Weber, Farhad Bakhtiary, Wilhelm Röll, Christoph Bourauel, Frank A Schildberg, Baravan Al-Kassou, Sebastian Zimmer, Daniela Wenzel, Bernd K Fleischmann

  • Mapping human microglial morphological diversity via handcrafted and deep learning-derived image features.

    iScience

    Authors: Kayhan Alvandipour, Amélie Weiss, Mona Mathews, Brenda Besemer, Michaela Segschneider, Zahra Hanifehlou, Christian Felski, Michael Peitz, Arnaud Ogier, Peter Sommer, Oliver Brüstle, Johannes H Wilbertz

  • Extracorporeal membrane oxygenation in Non-Immune Hydrops fetalis - a registry-based data analysis over the last 25 years.

    European journal of pediatrics

    Authors: Manuel Kuelshammer, Anna-Sophie Matzik, Andreas Hansmann, Johanna Moersdorf, Brigitte Strizek, Till Dresbach, Joachim Schmitt, Hemmen Sabir, Andreas Mueller, Lukas Schroeder

  • Large extracellular vesicles derived from red blood cells in coronary artery disease patients with anemia promote endothelial dysfunction.

    Journal of molecular and cellular cardiology

    Authors: Isabella Solga, Leon Götzmann, Vithya Yogathasan, Patricia Wischmann, Tin Yau Pang, Patricia Kleimann, Sebastian Temme, Lina Hofer, Anja Stefanski, Alexander Lang, Georg Nickenig, Christian Jung, Norbert Gerdes, Mohammed Rabiul Hosen, Malte Kelm, Ramesh Chennupati

  • C-terminal lysine residues localise NLRP10 at lipid droplets and govern NLRP10 oligomer formation.

    EMBO reports

    Authors: Timo-Daniel Voss, Christoph Winterberg, Adrian Beck, Clarissa Gottschild, Leonie Mueller, Selina M Enayat, Matthias Geyer, Thomas A Kufer

  • TGF-β and IL-2 differentially shape T follicular regulatory cell differentiation and stability in vitro.

    Cellular & molecular immunology

    Authors: Luisa Bach, Yinshui Chang, Olin Arteaga Transito, Mohammadamin Ghasemi, Lisa Maria Steinheuer, Teresa Steffen, Elena De Domenico, Thomas Ulas, F Thomas Wunderlich, Marc D Beyer, Kevin Thurley, Dirk Baumjohann

  • Stem-like precursors of exhausted Th cells upheld by a Tox-Myb-Eomes transcriptional hierarchy propagate Th cell responses in chronic infection.

    Immunity

    Authors: Lifen Wen, Chun-Hsi Su, Nikita Potemkin, Lachlan Dryburgh, Lei Qin, Sining Li, Marcela De Lima Moreira, Ashraful Haque, Xiye Sun, Vincenzo Cinella, Jan Schroeder, Carlson Tsui, Axel Kallies

  • Glucagon and beta-cell function changes before and after dietary weight loss-induced metabolic improvements in type 2 diabetes.

    Diabetes research and clinical practice

    Authors: Elena Lalama, Jiudan Zhang, Bettina Schuppelius, Marta Csanalosi, Kilian J A Ruether, Stefan Kabisch, Knut Mai, Nicolle Kraenkel, Eicke Latz, Anette Christ, Domenico Trico, Andrea Mari, Andreas F H Pfeiffer

  • HTZ-1/H2A.Z expression sustains transcriptional programs that regulate Caenorhabditis elegans lifespan.

    Mechanisms of ageing and development

    Authors: Beijia Xie, Enzo Scifo, Ioanna-Maria Menegatou, Rossella Erminia Ciliberti, Mrityunjoy Mondal, Yiru Wang, Antonia Piazzesi, Jialu Hu, Elena De Domenico, Stefan Paulusch, Diego De Stefani, Matthias Schmid, Dagmar Wachten, Marc D Beyer, Pierluigi Nicotera, Nasir Ahmad Aziz, Dan Ehninger, Daniele Bano

  • Substantia Nigra MRI markers are lower in Alzheimer's disease and are linked to general cognitive function.

    Brain communications

    Authors: Friedrich Krohn, Mousumi Sarkar, Hartmut Schütze, Panagiotis Iliopoulos, Lucía Penalba-Sánchez, Dorothea Hämmerer, Renat Yakupov, Falk Lüsebrink, Annika Spottke, Anja Schneider, Nina Roy, Enise Incesoy, Michael Heneka, Ingo Kilimann, Luca Kleineidam, Stefan J Teipel, Frederic Brosseron, Doreen Goerss, Wenzel Glanz, Matthias Schmid, Ayda Rostamzadeh, Michael Wagner, Klaus Fliessbach, Frank Olaf Jessen, Emrah Düzel, Matthew J Betts