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featured publications

  • Genetic and molecular landscape of comorbidities in people living with HIV.

    Nature medicine

    Authors: Javier Botey-Bataller, Nienke van Unen, Marc Blaauw, Willem A J W Vos, Louise van Eekeren, Nadira Vadaq, Vasiliki Matzaraki, Annelies Verbon, Albert L Groenendijk, Jéssica C Dos Santos, Maartje C P Cleophas, Janneke E Stalenhoef, Marvin A H Berrevoets, Xun Jiang, Manoj K Gupta, Nhan Nguyen, Cheng-Jian Xu, Leo A B Joosten, Mihai G Netea, André J A M van der Ven, Yang Li

  • A CDK11-dependent RNA polymerase II pause-checkpoint precedes CDK9-mediated transition to transcriptional elongation.

    Molecular cell

    Authors: Jennifer R Devlin, Ben Martin, Nenad Bartonicek, Keziah Ting, Zheng Fan, Izabela Todorovski, Filip Bjelosevic, Sandra Verschoor, Annette Ciccone, Joseph A Trapani, Attila Horvath, Emily Tinsley, Peter Fraser, Andrea Newbold, Jarrod J Sandow, Andrea Muscat, Kaylene J Simpson, Matthias Geyer, Stephin J Vervoort, Ricky W Johnstone

  • Image-based drug screening combined with molecular profiling identifies signatures and drivers of therapy resistance in pediatric AML.

    Cell reports. Medicine

    Authors: Ben Haladik, Margarita Maurer-Granofszky, Peter Zoescher, Raul Jimenez-Heredia, Alexandra Frohne, Anna Segarra-Roca, Chloe Casey, Felix Kartnig, Sarah Giuliani, Christina Rashkova, Peter Repiscak, Michael N Dworzak, Giulio Superti-Furga, Kaan Boztug

  • Clinical outcomes of the PAUL glaucoma implant in primary open-angle and pseudoexfoliative glaucoma eyes after failed glaucoma surgeries.

    Acta ophthalmologica

    Authors: Constance Liegl, Leonie Bourauel, Benjamin Aretz, Diana Samarghitan, Wolfgang Walz, Michael Petrak, Frank G Holz, Raffael Liegl, Karl Mercieca

  • Risk factors for dementia and cognitive impairment within 5 years after stroke: a prospective multicentre cohort study.

    The Lancet regional health. Europe

    Authors: Jule Filler, Marios K Georgakis, Daniel Janowitz, Marco Duering, Rong Fang, Anna Dewenter, Felix J Bode, Sebastian Stoesser, Christine Kindler, Peter Hermann, Christian H Nolte, Thomas G Liman, Lucia Kerti, Kathleen Bernkopf, Benno Ikenberg, Wenzel Glanz, Michael Wagner, Annika Spottke, Karin Waegemann, Michael Goertler, Silke Wunderlich, Matthias Endres, Inga Zerr, Gabor C Petzold, Martin Dichgans

  • [S3 guideline on sepsis-prevention, diagnosis, therapy, and follow-up care-update 2025].

    Medizinische Klinik, Intensivmedizin und Notfallmedizin

    Authors: Frank M Brunkhorst, Michael Adamzik, Hubertus Axer, Michael Bauer, Christian Bode, Hans-Georg Bone, Thorsten Brenner, Michael Bucher, Sascha David, Maximilian Dietrich, Christian Eckmann, Gunnar Elke, Torben Esser, Thomas Felbinger, Christine Geffers, Herwig Gerlach, Béatrice Grabein, Matthias Gründling, Ulf Günther, Stefan Hagel, Andreas Hecker, Stefan Henkel, Babila Janusan, Stefan John, Achim Jörres, Achim Kaasch, Stefan Kluge, Matthias Kochanek, Agnieszka Lajca, Gernot Marx, Konstantin Mayer, Patrick Meybohm, Onnen Mörer, Michael Oppert, Vladimir Patchev, Mathias Pletz, Christian Putensen, Tim Rahmel, Jenny Rosendahl, Rolf Rossaint, Bernd Salzberger, Michael Sander, Stefan Schaller, Christina Scharf-Janssen, Felix Schmitt, Matthias Unterberg, Markus Weigand, Arved Weimann, Sebastian Weis, Björn Weiß, Alexander Wolf, Alexander Zarbock

  • A genome-wide association study identifies new loci associated with response to SARS-CoV-2 mRNA-1273 vaccine in a cohort of healthy healthcare workers.

    Frontiers in immunology

    Authors: Antonio José Cabrera-Serrano, Lucía Ruiz-Durán, Juan Francisco Gutiérrez-Bautista, María Carretero-Fernández, Rob Ter Horst, Yang Li, Fernando Jesús Reyes-Zurita, Francisco José García-Verdejo, Mihai G Netea, Pedro Sánchez-Rovira, Miguel Ángel López-Nevot, Antonio Sampedro, Juan Sainz

  • The expanding role of the NLRP3 inflammasome from periodic fevers to therapeutic targets.

    Nature immunology

    Authors: Alexander N R Weber, Róisín M McManus, Veit Hornung, Matthias Geyer, Jasmin B Kuemmerle-Deschner, Eicke Latz

  • Effects of simulated Martian environmental stressors on specific human pathogen-immune system interactions.

    mBio

    Authors: Tommaso Zaccaria, Özlem Bulut, Anaisa V Ferreira, Margo Dona, Jeroen D Langereis, Rob J Mesman, Joppe Wesseling, Laura van Niftrik, Mihai G Netea, Petra Rettberg, Kristina Beblo-Vranesevic, Marien I de Jonge, Jorge Domínguez-Andrés

  • Plain language summary of publication of the 48-week results from the PULSAR study investigating how well a new dose of aflibercept works and how safe it is for people with wet age-related macular degeneration.

    Therapeutic advances in ophthalmology

    Authors: Paolo Lanzetta, Jean-François Korobelnik, Jeffrey S Heier, Sergio Leal, Frank G Holz, William Lloyd Clark, David Eichenbaum, Tomohiro Iida, Xiaodong Sun, Alyson J Berliner, Andrea Schulze, Thomas Schmelter, Ursula Schmidt-Ott, Xin Zhang, Robert Vitti, Karen W Chu, Kimberly Reed, Rohini Rao, Rafia Bhore, Yenchieh Cheng, Tien Y Wong