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featured publications

  • Active LXR signaling, coupled with elevated mitochondrial and glycolytic metabolism contributes to GM-CSF-induced trained immunity.

    Frontiers in immunology

    Authors: Yuanyuan Liu, Arslan Hamid, Hannah Hardege, Qian Zhang, Helena Körner, Merle Leffers, Noelia A Gonzalez, Gerhard Liebisch, Marcus Hoering, Hannes Findeisen, Katarzyna Placek, Mihai G Netea, Holger Reinecke, Dennis Schwarz, Yahya Sohrabi

  • Increased axial resolution OCT improves structure-function correlation of the disorganization of the retinal inner layers in diabetic retinal disease.

    Scientific reports

    Authors: Katharina Wall, Lilith P Arend, Leon von der Emde, Anna Sophia Jauch, Frank G Holz, Marlene Saßmannshausen, Thomas Ach

  • Targeting a Glutamic Acid in PDEδ with Fluoromethyl-Aryl Electrophiles Impairs K-Ras Signaling.

    Journal of medicinal chemistry

    Authors: Ruirui Zhang, Maxim A Huetzen, Aylin Binici, Pablo Martín-Gago, Raphael Gasper, Elena Rudashevskaya, Jie Liu, Chinta Nagaraju, Elena S Reckzeh, Alana S T Stuedle, Ann-Sophie Hopff, Andrea Mesaros, Anke Unger, Melanie Thelen, Petra Janning, H Christian Reinhardt, Slava Ziegler, Ron D Jachimowicz, Herbert Waldmann

  • Imaging-guided stratification in giant cell arteritis: prognostic and therapeutic implications.

    Therapeutic advances in musculoskeletal disease

    Authors: Juan Molina-Collada, Cristina Ponte, Valentin Sebastian Schäfer, Eugenio de Miguel

  • Sudan's complex genetic admixture history drives adaptation to malaria in Sudanese Copts.

    Proceedings of the National Academy of Sciences of the United States of America

    Authors: Laura Vilà-Valls, Jorge Garcia-Calleja, Javier Prado-Martinez, Elena Bosch, Aida M Andrés, Mihai G Netea, David Comas, Hisham Y Hassan

  • Integrating simulated and experimental data to identify mitochondrial bioenergetic defects in Parkinson's Disease models.

    PloS one

    Authors: Sandeep Chenna, Alvin Joselin, Pierre Theurey, Daniele Bano, Paola Pizzo, Maria Ankarcrona, David S Park, Jochen H Prehn, Niamh M C Connolly

  • Phase 3 study of intensive chemotherapy with or without dasatinib in core-binding factor acute myeloid leukemia.

    Blood

    Authors: Hartmut Döhner, Daniela Späth, Maral Saadati, Walter Fiedler, Katharina S Götze, Elisabeth Koller, Jörg Westermann, Wichard Vogel, Michael Heuser, Michael Lübbert, Hans-Joachim Tischler, Ulrich Germing, Lino Lars Teichmann, Lars Fransecky, Albert Wölfler, David Nachbaur, Bernd Hertenstein, Roland Schroers, Uwe M Martens, Stephanie von Harsdorf, Markus P Radsak, Gregor Aschauer, Stefanie Weißhaar, Andrea Corbacioglu, Anika Schrade, Verena I Gaidzik, Felicitas R Thol, Peter Paschka, Lars Bullinger, Axel Benner, Konstanze Döhner, Arnold Ganser

  • Frequent and clinically relevant germline DNA repair gene variants in young and familial myeloproliferative neoplasms.

    Blood cancer journal

    Authors: Robert Meyer, Maria Jimena Rodriguez, Madeline Caduc, Kim Kricheldorf, Matthias Begemann, Florian Kraft, Isabel Spier, Daniela Dey, Nergis Güzel, Kerstin Becker, Julian Baumeister, Marcelo A S de Toledo, Susanne Isfort, Ulrich Germing, Stefan Aretz, Tim H Brümmendorf, Ingo Kurth, Miriam Elbracht, Lino L Teichmann, Steffen Koschmieder

  • Effects of lipopolysaccharide on energy metabolism and immune cell activation in different microglia model systems.

    Brain, behavior, and immunity

    Authors: Susanne Michels, Johanna Eichberg, Fahd Alhamdan, Micha Engeser, Rafael Leite Dantas, Felix Sr Picard, Mona Mathews-Ajendra, Oliver Brüstle, Martin K-H Schäfer, Judith Alferink, Holger Garn, Markus Wöhr, Carsten Culmsee

  • Lymphotoxin-dependent elevated meningeal CXCL13:BAFF ratios drive gray matter injury.

    Nature immunology

    Authors: Ikbel Naouar, Andrei Pangan, Michelle Zuo, Syed Ali Raza, Kevin Champagne-Jorgensen, Jyot Patel, Angela Wang, Annie Pu, Lesley Ward, Jennifer S Y Ahn, Faizah N Sayeed, Jingwen Zhu, Elisabeth Pössnecker, Shoshana Spring, John G Sled, Bruno Cenni, Barbara Nuesslein-Hildesheim, Jeffrey L Browning, Anne-Katrin Pröbstel, Daniel S Reich, Jennifer L Gommerman, Valeria Ramaglia