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Featured publications

  • Site-specific genetic and functional signatures of aortic endothelial cells at aneurysm predilection sites in healthy and AngII ApoE mice.

    Angiogenesis

    Authors: Alexander Brückner, Adrian Brandtner, Sarah Rieck, Michaela Matthey, Caroline Geisen, Benedikt Fels, Marta Stei, Kristina Kusche-Vihrog, Bernd K Fleischmann, Daniela Wenzel

  • Exploring the role of innate lymphoid cells in the periodontium: insights into immunological dynamics during orthodontic tooth movement.

    Frontiers in immunology

    Authors: Eva Pastille, Anna Konermann

  • Brain and Ventricle Volume Alterations in Idiopathic Normal Pressure Hydrocephalus Determined by Artificial Intelligence-Based MRI Volumetry.

    Diagnostics (Basel, Switzerland)

    Authors: Zeynep Bendella, Veronika Purrer, Robert Haase, Stefan Zülow, Christine Kindler, Valerie Borger, Mohammed Banat, Franziska Dorn, Ullrich Wüllner, Alexander Radbruch, Frederic Carsten Schmeel

  • Top publication

    The life-saving benefit of dexamethasone in severe COVID-19 is linked to a reversal of monocyte dysregulation.

    Cell

    Authors: Rainer Knoll, Elisa T Helbig, Kilian Dahm, Olufemi Bolaji, Frederik Hamm, Oliver Dietrich, Martina van Uelft, Sophie Müller, Lorenzo Bonaguro, Jonas Schulte-Schrepping, Lev Petrov, Benjamin Krämer, Michael Kraut, Paula Stubbemann, Charlotte Thibeault, Sophia Brumhard, Heidi Theis, Gudrun Hack, Elena De Domenico, Jacob Nattermann, Matthias Becker, Marc D Beyer, David Hillus, Philipp Georg, Constantin Loers, Janina Tiedemann, Pinkus Tober-Lau, Lena Lippert, Belén Millet Pascual-Leone, Frank Tacke, Gernot Rohde, Norbert Suttorp, Martin Witzenrath, Antoine-Emmanuel Saliba, Thomas Ulas, Julia K Polansky, Birgit Sawitzki, Leif E Sander, Joachim L Schultze, Anna C Aschenbrenner, Florian Kurth

  • Peer-to-peer validation of Ki-67 scoring in a pathology quality circle as a tool to assess interobserver variability: are we better than we thought?

    APMIS : acta pathologica, microbiologica, et immunologica Scandinavica

    Authors: Marit Bernhardt, Leonie Weinhold, Christine Sanders, Oliver Hommerding, Jan-Frederic Lau, Marieta Toma, Verena Tischler, Matthias Schmid, Tomasz Zienkiewicz, Ralf Hildenbrand, Peter Gerlach, Hui Zhou, Martin Braun, Gunnar Müller, Erich Sieber, Christian Marko, Glen Kristiansen

  • Irinotecan and temozolomide in combination with dasatinib and rapamycin versus irinotecan and temozolomide for patients with relapsed or refractory neuroblastoma (RIST-rNB-2011): a multicentre, open-label, randomised, controlled, phase 2 trial.

    The Lancet. Oncology

    Authors: Selim Corbacioglu, Holger Lode, Susanne Ellinger, Florian Zeman, Meinolf Suttorp, Gabriele Escherich, Konrad Bochennek, Bernd Gruhn, Peter Lang, Marius Rohde, Klaus Michael Debatin, Daniel Steinbach, Andreas Beilken, Ruth Ladenstein, Rainer Spachtholz, Peter Heiss, Dirk Hellwig, Anja Tröger, Michael Koller, Karin Menhart, Markus J Riemenschneider, Saida Zoubaa, Silke Kietz, Marcus Jakob, Gunhild Sommer, Tilman Heise, Patrick Hundsdörfer, Ingrid Kühnle, Dagmar Dilloo, Stefan Schönberger, Georg Schwabe, Irene von Luettichau, Norbert Graf, Paul-Gerhardt Schlegel, Michael Frühwald, Norbert Jorch, Michael Paulussen, Dominik T Schneider, Markus Metzler, Alfred Leipold, Michaela Nathrath, Thomas Imschweiler, Holger Christiansen, Irene Schmid, Roman Crazzolara, Naghmeh Niktoreh, Gunnar Cario, Joerg Faber, Martin Demmert, Florian Babor, Birgit Fröhlich, Stefan Bielack, Toralf Bernig, Johann Greil, Angelika Eggert, Thorsten Simon, Juergen Foell

  • Blood immune cell profiling in adults with longstanding type 1 diabetes is associated with macrovascular complications.

    Frontiers in immunology

    Authors: Xuehui He, Xinhui Wang, Julia van Heck, Bram van Cranenbroek, Esther van Rijssen, Rinke Stienstra, Mihai G Netea, Irma Joosten, Cees J Tack, Hans J P M Koenen

  • Beneficial Effects of Synbiotics on the Gut Microbiome in Individuals with Low Fiber Intake: Secondary Analysis of a Double-Blind, Randomized Controlled Trial.

    Nutrients

    Authors: Aakash Mantri, Linda Klümpen, Waldemar Seel, Peter Krawitz, Peter Stehle, Bernd Weber, Leonie Koban, Hilke Plassmann, Marie-Christine Simon

  • Approximating facial expression effects on diagnostic accuracy via generative AI in medical genetics.

    Bioinformatics (Oxford, England)

    Authors: Tanviben Patel, Amna A Othman, Ömer Sümer, Fabio Hellman, Peter Krawitz, Elisabeth André, Molly E Ripper, Chris Fortney, Susan Persky, Ping Hu, Cedrik Tekendo-Ngongang, Suzanna Ledgister Hanchard, Kendall A Flaharty, Rebekah L Waikel, Dat Duong, Benjamin D Solomon

  • Efficient parameter estimation for ODE models of cellular processes using semi-quantitative data.

    Bioinformatics (Oxford, England)

    Authors: Domagoj Dorešić, Stephan Grein, Jan Hasenauer