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featured publications

  • Molecular characterization of FAM222B as a novel disease gene for dominant cardiovascular laterality defects.

    Scientific reports

    Authors: Nina Reitz, Jessica Lambertz, Öznur Yilmaz, Tobias T Lindenberg, Khadija Channab, Birgit Rau, Stefanie Ramrath, Enrico Mingardo, Hanna Schöpper, Bettina C Kirchmaier, Matthias Geyer, Gabriel C Dworschak, Johannes Breuer, Nicole Müller, Birthe Schaidinger, Alina C Hilger, Julia Hoefele, Korbinian M Riedhammer, Marc-Phillip Hitz, Gregor Dombrowsky, Hashim Abdul-Khaliq, Ulrike M M Bauer, Lars Fester, Heiko M Reutter, Katinka Breuer, Benjamin Odermatt

  • AI-enabled discovery and biochemical optimization of minibinders targeting cancer cell-surface proteins.

    Nature communications

    Authors: Bianca Broske, Benjamin A McEnroe, Sophie C Frechen, Tim N Kempchen, Caroline I Fandrey, Elisabeth Tan, Dominic Ferber, Michelle C R Yong, Marie Kleinert, Julia M Messmer, Peter Konopka, Alexander Hoch, Katja Blumenstock, Jan M P Tödtmann, Johannes Oldenburg, Heiko Rühl, Alexander Semaan, Marieta I Toma, Kristina Markova, Sebastian Kobold, Tim Rollenske, Matthias Geyer, Stephan Menzel, Tobias Bald, Jonathan L Schmid-Burgk, Gregor Hagelueken, Michael Hölzel

  • [Value of Clinical Video Registries for Research and Teaching in Minimally Invasive and Robotic Surgery].

    Zentralblatt fur Chirurgie

    Authors: Philipp Feodorovici, Lena Krings, Joachim Schmidt, Jörg C Kalff, Jan Arensmeyer, Hanno Matthaei

  • Association of Pretransplant Neutrophil-to-Lymphocyte Ratio With Major Adverse Cardiovascular Events in Kidney Transplant Recipients With Normal C-Reactive Protein Levels.

    Transplantation proceedings

    Authors: Uta Sonja Scheidt, Carola Ellen Kleine, Dominik Bös, Roxana Werberich, Louisa Werberich, Stephan Reinhard, Sibylle von Vietinghoff, Rainer Peter Woitas, Sebastian Schwab

  • A four-dimensional framework for classifying functional states in immune cells.

    iScience

    Authors: Rachel Brandes-Leibovitz, Gal Yankovitz, Eran Bacharach, Mihai G Netea, Evangelos J Giamarellos-Bourboulis, Irit Gat-Viks

  • Loss of type I interferon signaling in Kupffer cells triggers viral spread and fatal liver damage in a mouse model of Crimean-Congo hemorrhagic fever.

    PLoS pathogens

    Authors: Shintaro Yamada, Masayuki Shimojima, Takeshi Saito, Junki Maruyama, Hiroki Kato

  • Microglia activation by derepression of endogenous retroviruses drives inflammation and cellular senescence.

    Nature neuroscience

    Authors: Xin Yan, Christina Georgopoulou, Hang-Mao Lee, Ala Ahrari, Jenny Russ, Vijay Chandrasekar, Tim Ducksch, Giuliano Crispatzu, Valentina Talevi, Liang Qiao, Shobhit Agrawal, Sophie Crux, Andrew W Daman, Lena Wischhof, Miriam Stork, Margit Zweyer, Emma Dorotea Zanfi, Manon Chevallot-Beroux, Yunxiao Li, Elena De-Domenico, Dina Hüsson, Lorenzo Bonaguro, Yuanfang Li, Jonas Schulte-Schrepping, Qingyi Liang, Ketty Kessler, Dan Ehninger, Shahin Rafii, Jiankai Luo, Andreas Hermann, Annett Halle, Ying Liu, Elvira Mass, Melania Capasso, Hiroki Kato, Joachim L Schultze, Pierluigi Nicotera, Daniele Bano, Steven Zvi Josefowicz, Martin Fuhrmann, Thomas Ulas, Marc Beyer, Juntang Lin, Monique M B Breteler, N Ahmad Aziz, Paolo Salomoni

  • Distinct postnatal trajectories of mouse dendritic epidermal T cells and Langerhans cells independent of microbiota.

    Science advances

    Authors: David Obwegs, Alexander Oschwald, Lara M Koetter, Cylia Crisand, Sidney Doerr, Kerstin Bruder, Solveig Runge, Nisreen Ghanem, Vidmante Fuchs, Marleen Eckert, Christian Koengeter, Anna-Maria Schaffer, Lukas Amann, Sophia Papaioannou, Tim Rollenske, Julia Kolter, Daniel Erny, Marco Prinz, Susana Minguet, Wolfgang W Schamel, Philipp Henneke, Stephan P Rosshart, Katrin Kierdorf, Sagar

  • [Macular Telangiectasia Type 2 (MacTel) - Therapeutic options and new Developments].

    Klinische Monatsblatter fur Augenheilkunde

    Authors: Julia Harten, Kristina Raming, Lukas Goerdt, Frank Holz, Kristina Pfau

  • A novel diagnostic technology rapidly detects the presence of infection and defines antimicrobial sensitivities in organisms typical for joint infection.

    Bone & joint research

    Authors: Isabelle L Cochrane, Roselline Gabriella Gunarto, Frank Alexander Schildberg, Dieter Christian Wirtz, Robert J H Hammond, Phillip J Walmsley