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Featured publications

  • A PI3Kγ mimetic peptide triggers CFTR gating, bronchodilation, and reduced inflammation in obstructive airway diseases.

    Science translational medicine

    Authors: Alessandra Ghigo, Alessandra Murabito, Valentina Sala, Anna Rita Pisano, Serena Bertolini, Ambra Gianotti, Emanuela Caci, Alessio Montresor, Aiswarya Premchandar, Flora Pirozzi, Kai Ren, Angela Della Sala, Marco Mergiotti, Wito Richter, Eyleen de Poel, Michaela Matthey, Sara Caldrer, Rosa A Cardone, Federica Civiletti, Andrea Costamagna, Nancy L Quinney, Cosmin Butnarasu, Sonja Visentin, Maria Rosaria Ruggiero, Simona Baroni, Simonetta Geninatti Crich, Damien Ramel, Muriel Laffargue, Carlo G Tocchetti, Renzo Levi, Marco Conti, Xiao-Yun Lu, Paola Melotti, Claudio Sorio, Virginia De Rose, Fabrizio Facchinetti, Vito Fanelli, Daniela Wenzel, Bernd K Fleischmann, Marcus A Mall, Jeffrey Beekman, Carlo Laudanna, Martina Gentzsch, Gergely L Lukacs, Nicoletta Pedemonte, Emilio Hirsch

  • Generation and Characterization of an Inducible Cx43 Overexpression System in Mouse Embryonic Stem Cells.

    Cells

    Authors: Pia Niemann, Miriam Schiffer, Daniela Malan, Sabine Grünberg, Wilhelm Roell, Caroline Geisen, Bernd K Fleischmann

  • Author Correction: Macrophage-dependent IL-1β production induces cardiac arrhythmias in diabetic mice.

    Nature communications

    Authors: Gustavo Monnerat, Micaela L Alarcón, Luiz R Vasconcellos, Camila Hochman-Mendez, Guilherme Brasil, Rosana A Bassani, Oscar Casis, Daniela Malan, Leonardo H Travassos, Marisa Sepúlveda, Juan Ignacio Burgos, Martin Vila-Petroff, Fabiano F Dutra, Marcelo T Bozza, Claudia N Paiva, Adriana Bastos Carvalho, Adriana Bonomo, Bernd K Fleischmann, Antonio Carlos Campos de Carvalho, Emiliano Medei

  • High-Throughput Screening Platform in Postnatal Heart Cells and Chemical Probe Toolbox to Assess Cardiomyocyte Proliferation.

    Journal of medicinal chemistry

    Authors: Carmen Carrillo García, Cora Becker, Michael Forster, Stefan Lohmann, Patricia Freitag, Stefan Laufer, Sonja Sievers, Bernd K Fleischmann, Michael Hesse, Dennis Schade

  • Trophectoderm cell failure leads to peri-implantation lethality in Trpm7-deficient mouse embryos.

    Cell reports

    Authors: Aline Schütz, Christin Richter, Petra Weissgerber, Volodymyr Tsvilovskyy, Michael Hesse, Roger Ottenheijm, Frank Zimmermann, Stefanie Buchholz, Rebekka Medert, Sascha Dlugosz, Vladimir Kuryshev, Vladimir Benes, Veit Flockerzi, Bernd K Fleischmann, Adolfo Cavalié, Marc Freichel

  • Inhibition of Vascular Growth by Modulation of the Anandamide/Fatty Acid Amide Hydrolase Axis.

    Arteriosclerosis, thrombosis, and vascular biology

    Authors: Sarah Rieck, Sofia Kilgus, Johanna H Meyer, Hao Huang, Lan Zhao, Michaela Matthey, Xin Wang, Steffen Schmitz-Valckenberg, Bernd K Fleischmann, Daniela Wenzel

  • Bone marrow CD73 mesenchymal stem cells display increased stemness and promote fracture healing .

    Bone reports

    Authors: Kenichi Kimura, Martin Breitbach, Frank A Schildberg, Michael Hesse, Bernd K Fleischmann

  • Overexpression of human BAG3 in mice causes restrictive cardiomyopathy.

    Nature communications

    Authors: Kenichi Kimura, Astrid Ooms, Kathrin Graf-Riesen, Maithreyan Kuppusamy, Andreas Unger, Julia Schuld, Jan Daerr, Achim Lother, Caroline Geisen, Lutz Hein, Satoru Takahashi, Guang Li, Wilhelm Röll, Wilhelm Bloch, Peter F M van der Ven, Wolfgang A Linke, Sean M Wu, Pitter F Huesgen, Jörg Höhfeld, Dieter O Fürst, Bernd K Fleischmann, Michael Hesse

  • Macrocyclic Gq Protein Inhibitors FR900359 and/or YM-254890-Fit for Translation?

    ACS pharmacology & translational science

    Authors: Jonathan G Schlegel, Mariam Tahoun, Alexander Seidinger, Jan H Voss, Markus Kuschak, Stefan Kehraus, Marion Schneider, Michaela Matthey, Bernd K Fleischmann, Gabriele M König, Daniela Wenzel, Christa E Müller

  • Proximity to injury, but neither number of nuclei nor ploidy define pathological adaptation and plasticity in cardiomyocytes.

    Journal of molecular and cellular cardiology

    Authors: Michael Hesse, Rebecca Bednarz, Esther Carls, Cora Becker, Olga Bondareva, Achim Lother, Caroline Geisen, Martina Dreßen, Markus Krane, Wilhelm Roell, Lutz Hein, Bernd K Fleischmann, Ralf Gilsbach