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  • Bicuspid aortic valve stenosis is characterized by increased angiogenesis, inflammation, and a higher valvular-to-systemic calcification ratio than tricuspid aortic valve stenosis.

    Basic research in cardiology

    Authors: Alexander Brückner, Adrian Brandtner, Sarah Rieck, Hannah Billig, Werner Masson, Anna Weber, Farhad Bakhtiary, Wilhelm Röll, Christoph Bourauel, Frank A Schildberg, Baravan Al-Kassou, Sebastian Zimmer, Daniela Wenzel, Bernd K Fleischmann

  • Pressure Overload-Induced Ventricular Crosstalk Activates Regenerative Mechanisms in the Contralateral Ventricle in Neonatal Mice.

    Circulation

    Authors: Fabian Ebach, Julia Nicke, Tianyuan Hu, Hemmen Sabir, Andreas Müller, Bernd K Fleischmann, Mona Malek Mohammadi

  • Blockage of autophagy causes severe skeletal muscle disruption in a mouse model for myofibrillar myopathy 6.

    Nature communications

    Authors: Kerstin Filippi, Kathrin Graf-Riesen, Maithreyan Kuppusamy, Andreas Unger, Kenichi Kimura, Martin Matijass, Henrique Baeta, Magdalena Podlacha, Daniel Haertter, Alexei P Kudin, Martin Wiemann, Grzegorz Węgrzyn, Cornelia Kornblum, Jens Reimann, Wolfgang A Linke, Pitter F Huesgen, Wolfram S Kunz, Bernd K Fleischmann, Michael Hesse

  • Generation and characterization of a human induced pluripotent stem cell line (hiPSC) expressing the rEstus voltage sensor under doxycycline induction.

    Stem cell research

    Authors: Daniela Malan, Philipp Rühl, Stefan H Heinemann, Bernd K Fleischmann, Caroline Geisen

  • Generation of a homozygous TET2 knock-out hiPSC line for modeling of cardiovascular diseases associated with clonal hematopoiesis of indeterminate potential (CHIP).

    Stem cell research

    Authors: Christos Triantafyllou, Michael Peitz, Bernd K Fleischmann, Sarah Rieck

  • Beta arrestin 1 is a key regulator of pulmonary vascular tone.

    Proceedings of the National Academy of Sciences of the United States of America

    Authors: Leonard F Lebender, Alexander Seidinger, Michaela Matthey, Birte Dyck, Christian Schlamm, Abdullah Kaddoura, Maximilian Hausherr, Britta Eggers, Katrin Marcus, Evi Kostenis, Volkmar Gieselmann, Michael Adamzik, Anna Klinke, Björn Koos, Bernd K Fleischmann, Daniela Wenzel

  • Spatiotemporal dynamics of ecto-5'-nucleotidase (CD73) in mouse retina under physiological conditions.

    Development (Cambridge, England)

    Authors: Ryutaro Ishii, Keisuke Sakurai, Nao Hosomi, Bernd K Fleischmann, Seiya Mizuno, Kenichi Kimura, Hiromi Yanagisawa

  • Myeloperoxidase aggravates thoracic aortic aneurysm formation in Marfan disease.

    Cardiovascular research

    Authors: Dennis Mehrkens, Johannes Dohr, Felix Sebastian Nettersheim, Felix Ballmann, Jil Bastigkeit, Alexander Brückner, Simon Geissen, Lauren De Vore, Cedric Fitsch, Chris Diekmann, Andrea de la Fuente-Alonso, Patrik Schelemei, Felix Ruben Picard, Malte Kochen, Per Arkenberg, Anna Rappenecker, Maysam Ahdab, Harshal Nemade, Suchitra Narayan, Simon Braumann, Wiebke Kreuzberg, Alexander Hof, Henning Guthoff, Benedicta Quaye Mensah, Sebastian Lechner, Andrea Guala, Artur Evangelista, Gisela Teixido-Tura, J Francisco Nistal, Miguel R Campanero, Harald Kaemmerer, Zsuzsanna Wolf, Stefan Holdenrieder, Maarten Groenink, Mitzi van Andel, Arnout Mieremet, Susanne Pfeiler, Norbert Gerdes, Ulrich Flögel, Laura-Maria Zimmermann, Gerhard Sengle, Marie-Lisa Eich, Birgid Schömig-Markiefka, Matti Adam, Bernd K Fleischmann, Daniela Wenzel, Juan Miguel Redondo, Vivian de Waard, Anna Klinke, Stephan Baldus, Martin Mollenhauer, Holger Winkels

  • Hyaluronan synthase 3 deficiency lowers the incidence of ruptures of abdominal aortic aneurysms by reducing monocyte infiltration.

    Frontiers in immunology

    Authors: Viola Niemann, Fedor Brack, Luca Rolauer, Janet Kaczur, Patrick Petzsch, Karl Köhrer, Christine Quast, Norbert Gerdes, Pascal Bouvain, Katharina Voigt, Martina Krüger, Alexander Brückner, Bernd K Fleischmann, Daniela Wenzel, Philipp Barnowski, Laura-Marie Zimmermann, Sakine Simsekyilmaz, Timm Filler, Wiebke Ibing, Tobias Feige, Kim J Krott, Markus U Wagenhäuser, Jens W Fischer, Margitta Elvers, Gerhard Sengle, Ulrich Flögel, Christian Hundhausen, Tatsiana Suvorava, Maria Grandoch

  • Pregnancy hormones increase cardiac capillary density via the PGC-1α/ERRα/VEGF pathway in cardiomyocytes.

    Frontiers in cardiovascular medicine

    Authors: Michael Hesse, Daniel Korzus, Kristina Thaben, Nicole Wagner, Süleyman Ergün, Zoltan Arany, Bernd K Fleischmann