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Publications

featured publications

  • High-Throughput Screening Platform in Postnatal Heart Cells and Chemical Probe Toolbox to Assess Cardiomyocyte Proliferation.

    Journal of medicinal chemistry

    Authors: Carmen Carrillo García, Cora Becker, Michael Forster, Stefan Lohmann, Patricia Freitag, Stefan Laufer, Sonja Sievers, Bernd K Fleischmann, Michael Hesse, Dennis Schade

  • Trophectoderm cell failure leads to peri-implantation lethality in Trpm7-deficient mouse embryos.

    Cell reports

    Authors: Aline Schütz, Christin Richter, Petra Weissgerber, Volodymyr Tsvilovskyy, Michael Hesse, Roger Ottenheijm, Frank Zimmermann, Stefanie Buchholz, Rebekka Medert, Sascha Dlugosz, Vladimir Kuryshev, Vladimir Benes, Veit Flockerzi, Bernd K Fleischmann, Adolfo Cavalié, Marc Freichel

  • Inhibition of Vascular Growth by Modulation of the Anandamide/Fatty Acid Amide Hydrolase Axis.

    Arteriosclerosis, thrombosis, and vascular biology

    Authors: Sarah Rieck, Sofia Kilgus, Johanna H Meyer, Hao Huang, Lan Zhao, Michaela Matthey, Xin Wang, Steffen Schmitz-Valckenberg, Bernd K Fleischmann, Daniela Wenzel

  • Bone marrow CD73 mesenchymal stem cells display increased stemness and promote fracture healing .

    Bone reports

    Authors: Kenichi Kimura, Martin Breitbach, Frank A Schildberg, Michael Hesse, Bernd K Fleischmann

  • Overexpression of human BAG3 in mice causes restrictive cardiomyopathy.

    Nature communications

    Authors: Kenichi Kimura, Astrid Ooms, Kathrin Graf-Riesen, Maithreyan Kuppusamy, Andreas Unger, Julia Schuld, Jan Daerr, Achim Lother, Caroline Geisen, Lutz Hein, Satoru Takahashi, Guang Li, Wilhelm Röll, Wilhelm Bloch, Peter F M van der Ven, Wolfgang A Linke, Sean M Wu, Pitter F Huesgen, Jörg Höhfeld, Dieter O Fürst, Bernd K Fleischmann, Michael Hesse

  • Macrocyclic Gq Protein Inhibitors FR900359 and/or YM-254890-Fit for Translation?

    ACS pharmacology & translational science

    Authors: Jonathan G Schlegel, Mariam Tahoun, Alexander Seidinger, Jan H Voss, Markus Kuschak, Stefan Kehraus, Marion Schneider, Michaela Matthey, Bernd K Fleischmann, Gabriele M König, Daniela Wenzel, Christa E Müller

  • Proximity to injury, but neither number of nuclei nor ploidy define pathological adaptation and plasticity in cardiomyocytes.

    Journal of molecular and cellular cardiology

    Authors: Michael Hesse, Rebecca Bednarz, Esther Carls, Cora Becker, Olga Bondareva, Achim Lother, Caroline Geisen, Martina Dreßen, Markus Krane, Wilhelm Roell, Lutz Hein, Bernd K Fleischmann, Ralf Gilsbach

  • Heterotrimeric G Protein Subunit Gαq Is a Master Switch for Gβγ-Mediated Calcium Mobilization by Gi-Coupled GPCRs.

    Molecular cell

    Authors: Eva Marie Pfeil, Julian Brands, Nicole Merten, Timo Vögtle, Maddalena Vescovo, Ulrike Rick, Ina-Maria Albrecht, Nina Heycke, Kouki Kawakami, Yuki Ono, Francois Marie Ngako Kadji, Suzune Hiratsuka, Junken Aoki, Felix Häberlein, Michaela Matthey, Jaspal Garg, Stephanie Hennen, Marie-Lise Jobin, Kerstin Seier, Davide Calebiro, Alexander Pfeifer, Akos Heinemann, Daniela Wenzel, Gabriele M König, Bernhard Nieswandt, Bernd K Fleischmann, Asuka Inoue, Katharina Simon, Evi Kostenis

  • Sensitive LC-MS/MS Method for the Quantification of Macrocyclic Gα Protein Inhibitors in Biological Samples.

    Frontiers in chemistry

    Authors: Markus Kuschak, Jonathan G Schlegel, Marion Schneider, Stefan Kehraus, Jan H Voss, Alexander Seidinger, Michaela Matthey, Daniela Wenzel, Bernd K Fleischmann, Gabriele M König, Christa E Müller

  • Tetrahydroimidazo[1,2-a]pyrazine Derivatives: Synthesis and Evaluation as Gα -Protein Ligands.

    Chemistry (Weinheim an der Bergstrasse, Germany)

    Authors: Jim Küppers, Tobias Benkel, Suvi Annala, Kenichi Kimura, Lisa Reinelt, Bernd K Fleischmann, Evi Kostenis, Michael Gütschow