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  • Top publication

    A conserved isoleucine in the binding pocket of RIG-I controls immune tolerance to mitochondrial RNA.

    Nucleic acids research

    Authors: Ann Kristin de Regt, Kanchan Anand, Katrin Ciupka, Felix Bender, Karl Gatterdam, Bastian Putschli, David Fusshöller, Daniel Hilbig, Alexander Kirchhoff, Charlotte Hunkler, Steven Wolter, Agathe Grünewald, Christina Wallerath, Christine Schuberth-Wagner, Janos Ludwig, Katrin Paeschke, Eva Bartok, Gregor Hagelueken, Gunther Hartmann, Thomas Zillinger, Matthias Geyer, Martin Schlee

  • Assessment of technical and clinical utility of a bead-based flow cytometry platform for multiparametric phenotyping of CNS-derived extracellular vesicles.

    Cell communication and signaling : CCS

    Authors: Alexandra Brahmer, Carsten Geiß, Andriani Lygeraki, Elmo Neuberger, Theophilos Tzaridis, Tinh Thi Nguyen, Felix Luessi, Anne Régnier-Vigouroux, Gunther Hartmann, Perikles Simon, Kristina Endres, Stefan Bittner, Katrin S Reiners, Eva-Maria Krämer-Albers

  • Targeting nucleic acid sensors in tumor cells to reprogram biogenesis and RNA cargo of extracellular vesicles for T cell-mediated cancer immunotherapy.

    Cell reports. Medicine

    Authors: Simon Heidegger, Florian Stritzke, Sarah Dahl, Juliane Daßler-Plenker, Laura Joachim, Dominik Buschmann, Kaiji Fan, Carolin M Sauer, Nils Ludwig, Christof Winter, Stefan Enssle, Suqi Li, Markus Perl, André Görgens, Tobias Haas, Erik Thiele Orberg, Sascha Göttert, Catherine Wölfel, Thomas Engleitner, Isidro Cortés-Ciriano, Roland Rad, Wolfgang Herr, Bernd Giebel, Jürgen Ruland, Florian Bassermann, Christoph Coch, Gunther Hartmann, Hendrik Poeck

  • Dose Recommendations for Common Drugs in Patients with Liver Cirrhosis: A Systematic Literature Review.

    Clinical drug investigation

    Authors: Katharina Karsten Dafonte, Lisa Weber, Florian Chmielewski, Anna Maria Böhmer, Philipp Lutz, Gunther Hartmann, Ulrich Jaehde, Martin Coenen

  • Potential of Nucleic Acid Receptor Ligands to Improve Vaccination Efficacy against the Filarial Nematode .

    Vaccines

    Authors: Johanna F Scheunemann, Frederic Risch, Julia J Reichwald, Benjamin Lenz, Anna-Lena Neumann, Stephan Garbe, Stefan J Frohberger, Marianne Koschel, Jesuthas Ajendra, Maximilian Rothe, Eicke Latz, Christoph Coch, Gunther Hartmann, Beatrix Schumak, Achim Hoerauf, Marc P Hübner

  • Quantitative protein biomarker panels: a path to improved clinical practice through proteomics.

    EMBO molecular medicine

    Authors: Johannes Hartl, Florian Kurth, Kai Kappert, David Horst, Michael Mülleder, Gunther Hartmann, Markus Ralser

  • Increased IKKϵ protein stability ensures efficient type I interferon responses in conditions of TBK1 deficiency.

    Frontiers in immunology

    Authors: Julia Wegner, Charlotte Hunkler, Katrin Ciupka, Gunther Hartmann, Martin Schlee

  • RIG-I immunotherapy overcomes radioresistance in p53-positive malignant melanoma.

    Journal of molecular cell biology

    Authors: Silke Lambing, Yu Pan Tan, Paraskevi Vasileiadou, Stefan Holdenrieder, Patrick Müller, Christian Hagen, Stephan Garbe, Rayk Behrendt, Martin Schlee, Jasper G van den Boorn, Eva Bartok, Marcel Renn, Gunther Hartmann

  • Loss of the Immunomodulatory Transcription Factor BATF2 in Humans Is Associated with a Neurological Phenotype.

    Cells

    Authors: Gábor Zsurka, Maximilian L T Appel, Maximilian Nastaly, Kerstin Hallmann, Niels Hansen, Daniel Nass, Tobias Baumgartner, Rainer Surges, Gunther Hartmann, Eva Bartok, Wolfram S Kunz

  • Poly(I:C) Treatment Prevents Skin Tumor Formation in the Preclinical HPV8 Transgenic Mouse Model.

    The Journal of investigative dermatology

    Authors: Martin Hufbauer, Stephanie Rattay, Christian Hagen, Alexander Quaas, Herbert Pfister, Gunther Hartmann, Christoph Coch, Baki Akgül