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Publications

featured publications

  • Retinoic Acid-Inducible Gene I Activation Inhibits Human Respiratory Syncytial Virus Replication in Mammalian Cells and in Mouse and Ferret Models of Infection.

    The Journal of infectious diseases

    Authors: Lara S U Schwab, Rubaiyea Farrukee, Jean-François Eléouët, Marie-Anne Rameix-Welti, Sarah L Londrigan, Andrew G Brooks, Aeron C Hurt, Christoph Coch, Thomas Zillinger, Gunther Hartmann, Patrick C Reading

  • Deficiency for SAMHD1 activates MDA5 in a cGAS/STING-dependent manner.

    The Journal of experimental medicine

    Authors: Tina Schumann, Santiago Costas Ramon, Nadja Schubert, Mohamad Aref Mayo, Melanie Hega, Katharina Isabell Maser, Servi-Remzi Ada, Lukas Sydow, Mona Hajikazemi, Markus Badstübner, Patrick Müller, Yan Ge, Farhad Shakeri, Andreas Buness, Benjamin Rupf, Stefan Lienenklaus, Barbara Utess, Lina Muhandes, Michael Haase, Luise Rupp, Marc Schmitz, Thomas Gramberg, Nicolas Manel, Gunther Hartmann, Thomas Zillinger, Hiroki Kato, Stefan Bauer, Alexander Gerbaulet, Katrin Paeschke, Axel Roers, Rayk Behrendt

  • Innate sensing of mRNA vaccines.

    Current opinion in immunology

    Authors: Christine Wuebben, Eva Bartok, Gunther Hartmann

  • SAMHD1 controls innate immunity by regulating condensation of immunogenic self RNA.

    Molecular cell

    Authors: Shovamayee Maharana, Stefanie Kretschmer, Susan Hunger, Xiao Yan, David Kuster, Sofia Traikov, Thomas Zillinger, Marc Gentzel, Shobha Elangovan, Padmanava Dasgupta, Nagaraja Chappidi, Nadja Lucas, Katharina Isabell Maser, Henrike Maatz, Alexander Rapp, Virginie Marchand, Young-Tae Chang, Yuri Motorin, Norbert Hubner, Gunther Hartmann, Anthony A Hyman, Simon Alberti, Min Ae Lee-Kirsch

  • A novel serum extracellular vesicle protein signature to monitor glioblastoma tumor progression.

    International journal of cancer

    Authors: Theophilos Tzaridis, Johannes Weller, Daniel Bachurski, Farhad Shakeri, Christina Schaub, Peter Hau, Andreas Buness, Uwe Schlegel, Joachim-Peter Steinbach, Clemens Seidel, Roland Goldbrunner, Niklas Schäfer, Robert J Wechsler-Reya, Michael Hallek, Björn Scheffler, Martin Glas, Lothar Haeberle, Ulrich Herrlinger, Christoph Coch, Katrin S Reiners, Gunther Hartmann

  • Top publication

    Monocyte-derived macrophages aggravate pulmonary vasculitis via cGAS/STING/IFN-mediated nucleic acid sensing.

    The Journal of experimental medicine

    Authors: Nina Kessler, Susanne F Viehmann, Calvin Krollmann, Karola Mai, Katharina M Kirschner, Hella Luksch, Prasanti Kotagiri, Alexander M C Böhner, Dennis Huugen, Carina C de Oliveira Mann, Simon Otten, Stefanie A I Weiss, Thomas Zillinger, Kristiyana Dobrikova, Dieter E Jenne, Rayk Behrendt, Andrea Ablasser, Eva Bartok, Gunther Hartmann, Karl-Peter Hopfner, Paul A Lyons, Peter Boor, Angela Rösen-Wolff, Lino L Teichmann, Peter Heeringa, Christian Kurts, Natalio Garbi

  • Induction of Interferon-Stimulated Genes Correlates with Reduced Growth of Influenza A Virus in Lungs after RIG-I Agonist Treatment of Ferrets.

    Journal of virology

    Authors: Lara S U Schwab, Sarah L Londrigan, Andrew G Brooks, Aeron C Hurt, Anshupa Sahu, Yi-Mo Deng, Jean Moselen, Christoph Coch, Thomas Zillinger, Gunther Hartmann, Patrick C Reading

  • Expression of a Functional Mx1 Protein Is Essential for the Ability of RIG-I Agonist Prophylaxis to Provide Potent and Long-Lasting Protection in a Mouse Model of Influenza A Virus Infection.

    Viruses

    Authors: Lara S U Schwab, Fernando Villalón-Letelier, Melkamu B Tessema, Sarah L Londrigan, Andrew G Brooks, Aeron Hurt, Christoph Coch, Thomas Zillinger, Gunther Hartmann, Patrick C Reading

  • Human Beta Papillomavirus Type 8 E1 and E2 Proteins Suppress the Activation of the RIG-I-Like Receptor MDA5.

    Viruses

    Authors: Stephanie Rattay, Martin Hufbauer, Christian Hagen, Bastian Putschli, Christoph Coch, Baki Akgül, Gunther Hartmann

  • Influence on study outcomes of an inpatient study by the behavior of the study staff (PINgPOng): study protocol for a randomized clinical trial.

    Trials

    Authors: Martin Coenen, Ulrike Bingel, Matthias Zunhammer, Maria Soledad Berdaguer, Christine Fuhrmann, Rolf Fimmers, Jens Rengelshausen, Gunther Hartmann, Manfred Schedlowski, Christoph Coch