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  • Dose Recommendations for Drugs in Patients With Liver Cirrhosis (The ALIVe Study): Protocol for a Multiphase Validation and Consensus Study.

    JMIR research protocols

    Authors: Katharina Karsten Dafonte, Philipp Lutz, Christian Jansen, Christian P Strassburg, Robert Németh, Gunther Hartmann, Ulrich Jaehde, Martin Coenen

  • 5'-Triphosphate guanosine RNAs recruit GTP-binding proteins to suppress RIG-I/IFN type I signaling.

    Molecular cell

    Authors: Magdalena Wolczyk, Jacek Szymanski, Ivan Trus, Zara Naz, Nathalie Idlin, Michal Lechowski, Emilia Baranowska, Alicja Bis, Jakub Stanislaw Nowak, Tola Tame, Justyna Jackiewicz, Elzbieta Nowak, Christine Wuebben, Gunther Hartmann, Juri Rappsilber, Gracjan Michlewski

  • RIG-I Stimulation Enhances the Effector Function and Proliferation of Primary Human CD8+ T Cells.

    International journal of molecular sciences

    Authors: Adham Abuelola Mohamed, Christina Wallerath, Charlotte Hunkler, Gunther Hartmann, Sanda Stankovic, Andrew G Brooks, Martin Schlee

  • Recommendations on Drug Selection and Dose Adjustment for Patients with Liver Cirrhosis: Results from a Multidisciplinary Expert Panel.

    Clinical drug investigation

    Authors: Katharina Karsten Dafonte, Philipp Lutz, Christian Jansen, Marika Busse, Peter Dietrich, Katrin Farker, Hans-Peter Lipp, Jacob Nattermann, Tilman Sauerbruch, Sven Schmiedl, Dorothea Strobach, Jonel Trebicka, Dario Zocholl, Gunther Hartmann, Ulrich Jaehde, Martin Coenen

  • Poxvirus dsDNA genomes differentially activate AIM2 or NLRP3 inflammasomes in human primary cells.

    The EMBO journal

    Authors: Yonas M Tesfamariam, Maria H Christensen, Stefan Diehl, Tabea Klein, Julius M Lingnau, Sabine Normann, Elena Hagelauer, Miriam Herbert, Sophie Reimer, Richa P Joshi, Pujan Engels, Steffen Pritzl, Pietro Fontana, Thomas Zillinger, Gunther Hartmann, Anna Eis-Hübinger, Martin C Lam, Klaus J Walgenbach, Felix Meissner, Hao Wu, Florian I Schmidt

  • Modulating Placebo Effects in Clinical Trials: Study Team Briefing to Optimize Drug-Placebo Differences.

    Clinical and translational science

    Authors: Martin Coenen, Ulrike Bingel, Maria Soledad Berdaguer, Christine Fuhrmann, Robert Németh, Jens Rengelshausen, Gunther Hartmann, Christoph Coch, Manfred Schedlowski

  • Expression Analysis of let-7a-5p and miR-21-3p in Extracellular Vesicles Derived from Serum of NSCLC Patients.

    Biomedicines

    Authors: Dian Jamel Salih, Katrin S Reiners, Domenico Loizzi, Nicoletta Pia Ardò, Teresa Antonia Santantonio, Francesco Sollitto, Gunther Hartmann

  • Isolation and characterization of extracellular vesicles from EGFR mutated lung cancer cells.

    Clinical and experimental medicine

    Authors: Dian Jamel Salih, Katrin S Reiners, Roberta Alfieri, Ahmed Mohammed Salih, Zulema Antonia Percario, Mariantonietta Di Stefano, Sollitto Francesco, Elisabetta Affabris, Gunther Hartmann, Teresa Santantonio

  • Immunoengineering of a Photocaged 5´-triphosphate Oligoribonucleotide Ligand for Spatiotemporal Control of RIG-I Activation in Cancer.

    Angewandte Chemie (International ed. in English)

    Authors: Sandra Lewash, Vivien McKenney, Christine Wuebben, Janos Ludwig, Racha Hosni, Dirk Radzey, Marieta Toma, Martin Schlee, Eva Bartok, Thomas Zillinger, Alexander Heckel, Gunther Hartmann

  • Immune training enhances anti-viral responses and improves outcomes in Pax5 mice susceptible to chronic infection.

    EMBO molecular medicine

    Authors: Zhe Lu, Olivia Stencel, Wei Liu, Eleni Vasileiou, Haifeng C Xu, Piyush Pandey, Paweł Stachura, Abdelrahman Elwy, Anastassia Tsombal, Ann-Sophie Mai, Franziska Auer, Mina N F Morcos, Maximilian Seidl, Sarah Koziel, Peter-Martin Bruch, Sascha Dietrich, Sarah Elitzur, Gunther Hartmann, Karl S Lang, Stefan Janssen, Ute Fischer, Sanil Bhatia, Philipp A Lang, Arndt Borkhardt, Julia Hauer, Aleksandra A Pandyra