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featured publications

  • Active LXR signaling, coupled with elevated mitochondrial and glycolytic metabolism contributes to GM-CSF-induced trained immunity.

    Frontiers in immunology

    Authors: Yuanyuan Liu, Arslan Hamid, Hannah Hardege, Qian Zhang, Helena Körner, Merle Leffers, Noelia A Gonzalez, Gerhard Liebisch, Marcus Hoering, Hannes Findeisen, Katarzyna Placek, Mihai G Netea, Holger Reinecke, Dennis Schwarz, Yahya Sohrabi

  • Sudan's complex genetic admixture history drives adaptation to malaria in Sudanese Copts.

    Proceedings of the National Academy of Sciences of the United States of America

    Authors: Laura Vilà-Valls, Jorge Garcia-Calleja, Javier Prado-Martinez, Elena Bosch, Aida M Andrés, Mihai G Netea, David Comas, Hisham Y Hassan

  • A randomized controlled trial of precision bezlotoxumab treatment for Clostridioides difficile infection.

    Cell reports. Medicine

    Authors: Christos Psarrakis, Nikolaos-Renatos Tziolos, Vicky Matzarakis, Vinod Kumar, Emmanouil Stylianakis, Chrysanthi Sidiropoulou, Elisavet Tasouli, Konstantina Iliopoulou, Michael Samarkos, Symeon Metallidis, Sarah Georgiadou, Karolina Akinosoglou, Amalia Bolanou, Erifli Hatziagelaki, Alina Kostaki, Periklis Panagopoulos, Konstantinos Toutouzas, Haralarampos Milionis, Georgios Adamis, Garyfallia Poulakou, Malvina Lada, Athanasios Skoutelis, Zoi Alexiou, Styliani Symbardi, George Chrysos, Mihai G Netea, Evangelos J Giamarellos-Bourboulis

  • Systemically inducing trained immunity overcomes solid tumors' immunosuppressive microenvironment.

    Science advances

    Authors: Bram Priem, Lisa Willemsen, Tom Anbergen, Yuri van Elsas, Jeroen Deckers, David P Schrijver, Stijn R J Hofstraat, Iris V Messing, Jazz Munitz, Dionne Honing, Geoffrey Prévot, Yohana C Toner, Judit Morla, William Wang, Anna Ranzenigo, Isabella Sirchia, Tomas Post, Raphaël Duivenvoorden, Ewelina Kluza, Glenn A O Cremers, Joost H C M Kreijtz, Carlos Pérez-Medina, Mandy M T van Leent, Abraham J P Teunissen, Roy van der Meel, Yi Zhou, Chris Glass, Jordi Ochando, Leo A B Joosten, Zahi A Fayad, Romana T Netea-Maier, Mihai G Netea, Menno P J de Winther, Thijs J Beldman, Arjan W Griffioen, Willem J M Mulder

  • BCG and β-glucan primed monocytes yield dendritic cells that hamper the induction of pro-inflammatory T cell immunity.

    Cellular immunology

    Authors: Jorge Cuenca-Escalona, Robbin Kramer, Clara Marjalizo-Jimenez, Jorge Domínguez-Andrés, Mihai G Netea, Georgina Flórez-Grau, I Jolanda M de Vries, Sophie K Horrevorts

  • Urinary Proteomics as a Noninvasive Readout of Obesity-associated Inflammation.

    Journal of the Endocrine Society

    Authors: Esra Canki, Esther Kho, Ruud van Stiphout, Niels P Riksen, Mihai Netea, Leo A B Joosten, Rinke Stienstra, Joost Hoenderop

  • Induction of trained immunity in myeloid cells and their progenitors from thyroid cancer patients.

    Frontiers in immunology

    Authors: Pepijn van Houten, Prashant Changoer, Liesbeth van Emst, Han J Bonenkamp, Johannes H W de Wilt, Willemijn Hobo, Manita E J Bremmers, Mieke W H Roeven, Janneke E W Walraven, Petronella B Ottevanger, Willem J M Mulder, Mihai G Netea, Martin Jaeger, Romana T Netea-Maier

  • Long-term immune and epigenetic dysregulation following COVID-19.

    Clinical immunology (Orlando, Fla.)

    Authors: Chrysanthi Sidiropoulou, Garyphallia Poulakou, Evdoxia Kyriazopoulou, Elisavet Tasouli, Efthymia Giannitsioti, Anna Strikou, Maria Tsilika, Eirini Christaki, Vassiliki Rapti, Vassiliki Evangelopoulou, Nikoletta Rovina, Nathalie Iannotti, Emanuele Nicastri, Eleonora Taddei, Helena Florou, Andrea Angheben, Matteo Bassetti, Lorenzo Dagna, Antonio Torres, Spyros Foutadakis, George Adamis, Emmanouil Stylianakis, Giannis Vatsellas, Georgia Damoraki, Leda Efstratiou, Christina Damoulari, Konstantinos Leventogiannis, Achilleas Laskaratos, Panagiotis Koufargyris, Nikoletta Charalampaki, Paraskevi Chra, Aglaia Galanopoulou, Dimitris Thanos, Periklis Panagopoulos, Konstantinos Syrigos, Athanasios Ziogas, Rob Ter Horst, Jos W M van der Meer, Konstantina Iliopoulou, Francesco Saverio Serino, Maria Pavlaki, Pierluigi Del Vecchio, Laura Scorzolini, Alessandra Bandera, Agamemnon Bakakos, Styliani Sympardi, Haralampos Milionis, Mihai G Netea, Evangelos J Giamarellos-Bourboulis

  • Precision Immunotherapy to Improve Sepsis Outcomes: The ImmunoSep Randomized Clinical Trial.

    JAMA

    Authors: Evangelos J Giamarellos-Bourboulis, Antigone Kotsaki, Ioanna Kotsamidi, Aikaterini Efthymiou, Vasiliki Koutsoukou, Johannes Ehler, Alexandra Paridou, Frantzeska Frantzeskaki, Marcella C A Müller, Peter Pickkers, Sylvain Meylan, Ioannis Nikolopoulos, Mihaela Lupse, Alexandra Gavala, Glykeria Vlachogianni, Nicky Solomonidi, Antonia Alevizou, Eumorfia Kondili, Eleni Antoniadou, Maria Nakou, Nikolaos Markou, Erifili Hatziagelaki, Athanassios Prekates, Apostolos Komnos, Lieke Bakkerus, Marleen A Slim, George N Dalekos, Areti Karapanagiotou, Sofia Ktena, Gennaro De Pascale, Vassileios Koulouras, Christos Psarrakis, Eleni Massa, Konstantina Dakou, Chrisoula Pazvanti, Aikaterini Ioakeimidou, Iraklis Tsangaris, Nikolaos Antonakos, Alexander P J Vlaar, Souzana Anisoglou, Thierry Calandra, Vasilios Papaioannou, Pavlos Myrianthefs, Maria Patrani, Ioannis Alamanos, Massimo Antonelli, Jos W M van der Meer, Tom van der Poll, W Joost Wiersinga, Maria Ntaganou, Eleni Gkeka, Michael Bauer, Eleni Mouloudi, Mihai G Netea

  • Innate immune cell function in statin-treated patients with severe hypercholesterolemia is comparable to normocholesterolemic individuals: A cross-sectional study.

    Atherosclerosis plus

    Authors: Harsh Bahrar, Kim Steward, Liesbeth van Emst, Nils Rother, Jeanine E Roeters van Lennep, Mihai G Netea, Siroon Bekkering, Niels P Riksen