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featured publications

  • The effect of BCG vaccination on systemic inflammation in neonates.

    Vaccine

    Authors: Valerie A C M Koeken, Thomas N Nissen, Nina M Birk, Collins K Boahen, Reinout van Crevel, Vinod Kumar, Yang Li, Peter Aaby, Christine S Benn, Mihai G Netea

  • Longitudinal plasma proteomic signatures of elite and viremic spontaneous HIV controllers.

    Nature communications

    Authors: Nadira Vadaq, Albert L Groenendijk, Jéssica C Dos Santos, Kavita Mehta, Ferdinand W N M Wit, Wilhelm A J W Vos, Martinus J T Blaauw, Louise E van Eekeren, Laurens Lambrechts, Sofie Rutsaert, Erni J Nelwan, Cheng-Jian Xu, Leo A B Joosten, Quirijn de Mast, Vasiliki Matzaraki, Jan van Lunzen, Casper Rokx, Annelies Verbon, Mihai G Netea, Linos Vandekerckhove, André J A M van der Ven

  • Integrated transcriptomic and proteomic profiling identifies an interferon-dependent inflammatory endotype in sepsis.

    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

    Authors: Andrian Fratea, Anca-Lelia Riza, Florentina Dumitrescu, Stefania Dorobantu, Andrei Pirvu, Adina Dragos, Andra Grigorescu, Ioana Streata, Mihai G Netea, Vinod Kumar, Collins K Boahen

  • Cytokine storm.

    Nature reviews. Disease primers

    Authors: Rajendra Karki, Mihai G Netea, Caroline Diorio, Thirumala-Devi Kanneganti

  • A distinct monocyte transcriptional state links systemic immune dysregulation to pulmonary impairment in long COVID.

    Nature immunology

    Authors: Saumya Kumar, Chaofan Li, Liang Zhou, Qiuyao Zhan, Ahmed Alaswad, Sonja Volland, Bibiana Costa, Simon Alexander Krooss, Isabel Klefenz, Hagen Schmaus, Antonia Zeuzem, Dorothee von Witzendorff, Helena Lickei, Lea Pueschel, Anke R M Kraft, Markus Cornberg, Andreas Rembert Koczulla, Isabell Pink, Marius M Hoeper, Cheng-Jian Xu, Susanne Häussler, Miriam Wiestler, Mihai G Netea, Thomas Illig, Jie Sun, Yang Li

  • Functional and transcriptional senescence profiles of CD8+ T cells associate with the presence of carotid plaques in people living with HIV.

    The Journal of infectious diseases

    Authors: Marc J T Blaauw, Adriana Navas, Victoria Rios Vásquez, Nadira Vadaq, Marvin A H Berrevoets, Twan Otten, Wilhelm A J W Vos, Louise E van Eekeren, Albert L Groenendijk, Gert Weijers, Esther Lutgens, Hans J P M Koenen, Marien I de Jonge, Mihai G Netea, Joost H W Rutten, Andre J A M van der Ven, Niels P Riksen

  • Active LXR signaling, coupled with elevated mitochondrial and glycolytic metabolism contributes to GM-CSF-induced trained immunity.

    Frontiers in immunology

    Authors: Yuanyuan Liu, Arslan Hamid, Hannah Hardege, Qian Zhang, Helena Körner, Merle Leffers, Noelia A Gonzalez, Gerhard Liebisch, Marcus Hoering, Hannes Findeisen, Katarzyna Placek, Mihai G Netea, Holger Reinecke, Dennis Schwarz, Yahya Sohrabi

  • Sudan's complex genetic admixture history drives adaptation to malaria in Sudanese Copts.

    Proceedings of the National Academy of Sciences of the United States of America

    Authors: Laura Vilà-Valls, Jorge Garcia-Calleja, Javier Prado-Martinez, Elena Bosch, Aida M Andrés, Mihai G Netea, David Comas, Hisham Y Hassan

  • A randomized controlled trial of precision bezlotoxumab treatment for Clostridioides difficile infection.

    Cell reports. Medicine

    Authors: Christos Psarrakis, Nikolaos-Renatos Tziolos, Vicky Matzarakis, Vinod Kumar, Emmanouil Stylianakis, Chrysanthi Sidiropoulou, Elisavet Tasouli, Konstantina Iliopoulou, Michael Samarkos, Symeon Metallidis, Sarah Georgiadou, Karolina Akinosoglou, Amalia Bolanou, Erifli Hatziagelaki, Alina Kostaki, Periklis Panagopoulos, Konstantinos Toutouzas, Haralarampos Milionis, Georgios Adamis, Garyfallia Poulakou, Malvina Lada, Athanasios Skoutelis, Zoi Alexiou, Styliani Symbardi, George Chrysos, Mihai G Netea, Evangelos J Giamarellos-Bourboulis

  • Systemically inducing trained immunity overcomes solid tumors' immunosuppressive microenvironment.

    Science advances

    Authors: Bram Priem, Lisa Willemsen, Tom Anbergen, Yuri van Elsas, Jeroen Deckers, David P Schrijver, Stijn R J Hofstraat, Iris V Messing, Jazz Munitz, Dionne Honing, Geoffrey Prévot, Yohana C Toner, Judit Morla, William Wang, Anna Ranzenigo, Isabella Sirchia, Tomas Post, Raphaël Duivenvoorden, Ewelina Kluza, Glenn A O Cremers, Joost H C M Kreijtz, Carlos Pérez-Medina, Mandy M T van Leent, Abraham J P Teunissen, Roy van der Meel, Yi Zhou, Chris Glass, Jordi Ochando, Leo A B Joosten, Zahi A Fayad, Romana T Netea-Maier, Mihai G Netea, Menno P J de Winther, Thijs J Beldman, Arjan W Griffioen, Willem J M Mulder