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featured publications

  • A distinct monocyte transcriptional state links systemic immune dysregulation to pulmonary impairment in long COVID.

    Nature immunology

    Authors: Saumya Kumar, Chaofan Li, Liang Zhou, Qiuyao Zhan, Ahmed Alaswad, Sonja Volland, Bibiana Costa, Simon Alexander Krooss, Isabel Klefenz, Hagen Schmaus, Antonia Zeuzem, Dorothee von Witzendorff, Helena Lickei, Lea Pueschel, Anke R M Kraft, Markus Cornberg, Andreas Rembert Koczulla, Isabell Pink, Marius M Hoeper, Cheng-Jian Xu, Susanne Häussler, Miriam Wiestler, Mihai G Netea, Thomas Illig, Jie Sun, Yang Li

  • Active LXR signaling, coupled with elevated mitochondrial and glycolytic metabolism contributes to GM-CSF-induced trained immunity.

    Frontiers in immunology

    Authors: Yuanyuan Liu, Arslan Hamid, Hannah Hardege, Qian Zhang, Helena Körner, Merle Leffers, Noelia A Gonzalez, Gerhard Liebisch, Marcus Hoering, Hannes Findeisen, Katarzyna Placek, Mihai G Netea, Holger Reinecke, Dennis Schwarz, Yahya Sohrabi

  • Functional and transcriptional senescence profiles of CD8+ T cells associate with the presence of carotid plaques in people living with HIV.

    The Journal of infectious diseases

    Authors: Marc J T Blaauw, Adriana Navas, Victoria Rios Vásquez, Nadira Vadaq, Marvin A H Berrevoets, Twan Otten, Wilhelm A J W Vos, Louise E van Eekeren, Albert L Groenendijk, Gert Weijers, Esther Lutgens, Hans J P M Koenen, Marien I de Jonge, Mihai G Netea, Joost H W Rutten, Andre J A M van der Ven, Niels P Riksen

  • Sudan's complex genetic admixture history drives adaptation to malaria in Sudanese Copts.

    Proceedings of the National Academy of Sciences of the United States of America

    Authors: Laura Vilà-Valls, Jorge Garcia-Calleja, Javier Prado-Martinez, Elena Bosch, Aida M Andrés, Mihai G Netea, David Comas, Hisham Y Hassan

  • A randomized controlled trial of precision bezlotoxumab treatment for Clostridioides difficile infection.

    Cell reports. Medicine

    Authors: Christos Psarrakis, Nikolaos-Renatos Tziolos, Vicky Matzarakis, Vinod Kumar, Emmanouil Stylianakis, Chrysanthi Sidiropoulou, Elisavet Tasouli, Konstantina Iliopoulou, Michael Samarkos, Symeon Metallidis, Sarah Georgiadou, Karolina Akinosoglou, Amalia Bolanou, Erifli Hatziagelaki, Alina Kostaki, Periklis Panagopoulos, Konstantinos Toutouzas, Haralarampos Milionis, Georgios Adamis, Garyfallia Poulakou, Malvina Lada, Athanasios Skoutelis, Zoi Alexiou, Styliani Symbardi, George Chrysos, Mihai G Netea, Evangelos J Giamarellos-Bourboulis

  • Systemically inducing trained immunity overcomes solid tumors' immunosuppressive microenvironment.

    Science advances

    Authors: Bram Priem, Lisa Willemsen, Tom Anbergen, Yuri van Elsas, Jeroen Deckers, David P Schrijver, Stijn R J Hofstraat, Iris V Messing, Jazz Munitz, Dionne Honing, Geoffrey Prévot, Yohana C Toner, Judit Morla, William Wang, Anna Ranzenigo, Isabella Sirchia, Tomas Post, Raphaël Duivenvoorden, Ewelina Kluza, Glenn A O Cremers, Joost H C M Kreijtz, Carlos Pérez-Medina, Mandy M T van Leent, Abraham J P Teunissen, Roy van der Meel, Yi Zhou, Chris Glass, Jordi Ochando, Leo A B Joosten, Zahi A Fayad, Romana T Netea-Maier, Mihai G Netea, Menno P J de Winther, Thijs J Beldman, Arjan W Griffioen, Willem J M Mulder

  • BCG and β-glucan primed monocytes yield dendritic cells that hamper the induction of pro-inflammatory T cell immunity.

    Cellular immunology

    Authors: Jorge Cuenca-Escalona, Robbin Kramer, Clara Marjalizo-Jimenez, Jorge Domínguez-Andrés, Mihai G Netea, Georgina Flórez-Grau, I Jolanda M de Vries, Sophie K Horrevorts

  • Urinary Proteomics as a Noninvasive Readout of Obesity-associated Inflammation.

    Journal of the Endocrine Society

    Authors: Esra Canki, Esther Kho, Ruud van Stiphout, Niels P Riksen, Mihai Netea, Leo A B Joosten, Rinke Stienstra, Joost Hoenderop

  • Induction of trained immunity in myeloid cells and their progenitors from thyroid cancer patients.

    Frontiers in immunology

    Authors: Pepijn van Houten, Prashant Changoer, Liesbeth van Emst, Han J Bonenkamp, Johannes H W de Wilt, Willemijn Hobo, Manita E J Bremmers, Mieke W H Roeven, Janneke E W Walraven, Petronella B Ottevanger, Willem J M Mulder, Mihai G Netea, Martin Jaeger, Romana T Netea-Maier

  • Long-term immune and epigenetic dysregulation following COVID-19.

    Clinical immunology (Orlando, Fla.)

    Authors: Chrysanthi Sidiropoulou, Garyphallia Poulakou, Evdoxia Kyriazopoulou, Elisavet Tasouli, Efthymia Giannitsioti, Anna Strikou, Maria Tsilika, Eirini Christaki, Vassiliki Rapti, Vassiliki Evangelopoulou, Nikoletta Rovina, Nathalie Iannotti, Emanuele Nicastri, Eleonora Taddei, Helena Florou, Andrea Angheben, Matteo Bassetti, Lorenzo Dagna, Antonio Torres, Spyros Foutadakis, George Adamis, Emmanouil Stylianakis, Giannis Vatsellas, Georgia Damoraki, Leda Efstratiou, Christina Damoulari, Konstantinos Leventogiannis, Achilleas Laskaratos, Panagiotis Koufargyris, Nikoletta Charalampaki, Paraskevi Chra, Aglaia Galanopoulou, Dimitris Thanos, Periklis Panagopoulos, Konstantinos Syrigos, Athanasios Ziogas, Rob Ter Horst, Jos W M van der Meer, Konstantina Iliopoulou, Francesco Saverio Serino, Maria Pavlaki, Pierluigi Del Vecchio, Laura Scorzolini, Alessandra Bandera, Agamemnon Bakakos, Styliani Sympardi, Haralampos Milionis, Mihai G Netea, Evangelos J Giamarellos-Bourboulis