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featured publications

  • Distinct metabolic perturbations link liver steatosis and incident CVD in lean but not obese PWH.

    BMC medicine

    Authors: Louise E van Eekeren, Nadira Vadaq, Marc J T Blaauw, Albert L Groenendijk, Wilhelm A J W Vos, Erni J Nelwan, Annelies Verbon, Janneke E Stalenhoef, Marvin A H Berrevoets, Jan van Lunzen, Mihai G Netea, Gert Weijers, Niels P Riksen, Joost H W Rutten, Quirijn de Mast, Eric T T L Tjwa, Leo A B Joosten, André J A M van der Ven

  • Is systemic dissemination of BCG following neonatal vaccination required for protection against M. tuberculosis?

    The Journal of infectious diseases

    Authors: Tobias R Kollmann, Nelly Amenyogbe, Frederik Schaltz-Buchholzer, Ole Bæk, James Campbell, David J Lynn, Anita J Campbell, Peter Aaby, Christine Stabell Benn, Mihai G Netea, Maziar Divangahi

  • Nature-inspired platform nanotechnology for RNA delivery to myeloid cells and their bone marrow progenitors.

    Nature nanotechnology

    Authors: Stijn R J Hofstraat, Tom Anbergen, Robby Zwolsman, Jeroen Deckers, Yuri van Elsas, Mirre M Trines, Iris Versteeg, Daniek Hoorn, Gijs W B Ros, Branca M Bartelet, Merel M A Hendrikx, Youssef B Darwish, Teun Kleuskens, Francisca Borges, Rianne J F Maas, Lars M Verhalle, Willem Tielemans, Pieter Vader, Olivier G de Jong, Tommaso Tabaglio, Dave Keng Boon Wee, Abraham J P Teunissen, Eliane Brechbühl, Henk M Janssen, P Michel Fransen, Anne de Dreu, David P Schrijver, Bram Priem, Yohana C Toner, Thijs J Beldman, Mihai G Netea, Willem J M Mulder, Ewelina Kluza, Roy van der Meel

  • Borrelia burgdorferi sensu lato inhibits CIITA transcription through pSTAT3 activation and enhanced SOCS1 and SOCS3 expression leading to limited IFN-γ production.

    Ticks and tick-borne diseases

    Authors: Michelle A E Brouwer, Zara Karami, Samuel T Keating, Hedwig Vrijmoeth, Heidi L M Lemmers, Helga Dijkstra, Frank L van de Veerdonk, Mihaela Lupse, Hadewych J M Ter Hofstede, Mihai G Netea, Leo A B Joosten

  • Effect of Bacille Calmette-Guérin vaccination on immune responses to SARS-CoV-2 and COVID-19 vaccination.

    Clinical & translational immunology

    Authors: Nicole L Messina, Susie Germano, Amy W Chung, Carolien E van de Sandt, Natalie E Stevens, Lilith F Allen, Rhian Bonnici, Julio Croda, Claudio Counoupas, Branka Grubor-Bauk, Ebene R Haycroft, Katherine Kedzierska, Ellie McDonald, Rebecca McElroy, Mihai G Netea, Boris Novakovic, Kirsten P Perrett, Laure F Pittet, Ruth A Purcell, Kanta Subbarao, James A Triccas, David J Lynn, Nigel Curtis

  • Improving the odds of survival: transgenerational effects of infections.

    EMBO molecular medicine

    Authors: Victoria M Spanou, Theano P Andriopoulou, Evangelos J Giamarellos-Bourboulis, Mihai G Netea

  • Lactic acid in the vaginal milieu modulates the -host interaction.

    Virulence

    Authors: Diletta Rosati, Marisa Valentine, Mariolina Bruno, Arnab Pradhan, Axel Dietschmann, Martin Jaeger, Ian Leaves, Frank L van de Veerdonk, Leo A B Joosten, Sumita Roy, Mark H T Stappers, Neil A R Gow, Bernhard Hube, Alistair J P Brown, Mark S Gresnigt, Mihai G Netea

  • Early and delayed STAT1-dependent responses drive local trained immunity of macrophages in the spleen.

    eLife

    Authors: Aryeh Solomon, Noa Bossel Ben-Moshe, Dotan Hoffman, Sébastien Trzebanski, Dror Yehezkel, Leia Vainman, Mihai G Netea, Roi Avraham

  • Plasma Proteomic Signature as a Predictor of Age Advancement in People Living With HIV.

    Aging cell

    Authors: Adriana Navas, Vasiliki Matzaraki, Louise E van Eekeren, Marc J T Blaauw, Albert L Groenendijk, Wilhelm A J W Vos, Maartje Jacobs-Cleophas, Jéssica C Dos Santos, André J A M van der Ven, Leo A B Joosten, Mihai G Netea

  • Host-Directed Therapy in Pandemic Preparedness.

    JAMA

    Authors: Mihai G Netea, Frank L van de Veerdonk, Evangelos J Giamarellos-Bourboulis