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featured publications

  • Emerging principles of primary cilia dynamics in controlling tissue organization and function.

    The EMBO journal

    Authors: Jay Gopalakrishnan, Kerstin Feistel, Benjamin M Friedrich, Anne Grapin-Botton, Nathalie Jurisch-Yaksi, Elvira Mass, David U Mick, Roman-Ulrich Müller, Helen May-Simera, Bernhard Schermer, Miriam Schmidts, Peter Walentek, Dagmar Wachten

  • Engineering bacteriophytochrome-coupled photoactivated adenylyl cyclases for enhanced optogenetic cAMP modulation.

    Journal of molecular biology

    Authors: Qianzhao Xu, Arend Vogt, Fabian Frechen, Chengwei Yi, Melike Küçükerden, Neville Ngum, Laia Sitjà Roqueta, Andreas Greiner, Rhein Parri, Mercè Masana, Nikolaus Wenger, Dagmar Wachten, Andreas Möglich

  • The cilia mechanosensation debate gets (bio)physical.

    Nature reviews. Nephrology

    Authors: Dagmar Wachten, Pleasantine Mill

  • Top publication

    Mitochondrial damage activates the NLRP10 inflammasome.

    Nature immunology

    Authors: Tomasz Próchnicki, Matilde B Vasconcelos, Kim S Robinson, Matthew S J Mangan, Dennis De Graaf, Kateryna Shkarina, Marta Lovotti, Lena Standke, Romina Kaiser, Rainer Stahl, Fraser G Duthie, Maximilian Rothe, Kateryna Antonova, Lea-Marie Jenster, Zhi Heng Lau, Sarah Rösing, Nora Mirza, Clarissa Gottschild, Dagmar Wachten, Claudia Günther, Thomas A Kufer, Florian I Schmidt, Franklin L Zhong, Eicke Latz

  • Induced Remodelling of Astrocytes In Vitro and In Vivo by Manipulation of Astrocytic RhoA Activity.

    Cells

    Authors: Cátia Domingos, Franziska E Müller, Stefan Passlick, Dagmar Wachten, Evgeni Ponimaskin, Martin K Schwarz, Susanne Schoch, André Zeug, Christian Henneberger

  • AdipoQ-a simple, open-source software to quantify adipocyte morphology and function in tissues and in vitro.

    Molecular biology of the cell

    Authors: Katharina Sieckmann, Nora Winnerling, Mylene Huebecker, Philipp Leyendecker, Dalila Juliana Silva Ribeiro, Thorsten Gnad, Alexander Pfeifer, Dagmar Wachten, Jan N Hansen

  • Measurement of ciliary beating and fluid flow in the zebrafish adult telencephalon.

    STAR protocols

    Authors: Inyoung Jeong, Jan Niklas Hansen, Dagmar Wachten, Nathalie Jurisch-Yaksi

  • A cAMP signalosome in primary cilia drives gene expression and kidney cyst formation.

    EMBO reports

    Authors: Jan N Hansen, Fabian Kaiser, Philipp Leyendecker, Birthe Stüven, Jens-Henning Krause, Fatemeh Derakhshandeh, Jaazba Irfan, Tommy J Sroka, Kenley M Preval, Paurav B Desai, Michael Kraut, Heidi Theis, Anna-Dorothee Drews, Elena De-Domenico, Kristian Händler, Gregory J Pazour, David J P Henderson, David U Mick, Dagmar Wachten

  • Primary cilia and their effects on immune cell functions and metabolism: a model.

    Trends in immunology

    Authors: Ernesto Picon-Galindo, Eicke Latz, Dagmar Wachten

  • Simultaneous recording of multiple cellular signaling events by frequency- and spectrally-tuned multiplexing of fluorescent probes.

    eLife

    Authors: Michelina Kierzek, Parker E Deal, Evan W Miller, Shatanik Mukherjee, Dagmar Wachten, Arnd Baumann, U Benjamin Kaupp, Timo Strünker, Christoph Brenker