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featured publications

  • A cAMP signalosome in primary cilia drives gene expression and kidney cyst formation.

    EMBO reports

    Authors: Jan N Hansen, Fabian Kaiser, Philipp Leyendecker, Birthe Stüven, Jens-Henning Krause, Fatemeh Derakhshandeh, Jaazba Irfan, Tommy J Sroka, Kenley M Preval, Paurav B Desai, Michael Kraut, Heidi Theis, Anna-Dorothee Drews, Elena De-Domenico, Kristian Händler, Gregory J Pazour, David J P Henderson, David U Mick, Dagmar Wachten

  • Primary cilia and their effects on immune cell functions and metabolism: a model.

    Trends in immunology

    Authors: Ernesto Picon-Galindo, Eicke Latz, Dagmar Wachten

  • Simultaneous recording of multiple cellular signaling events by frequency- and spectrally-tuned multiplexing of fluorescent probes.

    eLife

    Authors: Michelina Kierzek, Parker E Deal, Evan W Miller, Shatanik Mukherjee, Dagmar Wachten, Arnd Baumann, U Benjamin Kaupp, Timo Strünker, Christoph Brenker

  • Diversity and function of motile ciliated cell types within ependymal lineages of the zebrafish brain.

    Cell reports

    Authors: Percival P D'Gama, Tao Qiu, Mehmet Ilyas Cosacak, Dheeraj Rayamajhi, Ahsen Konac, Jan Niklas Hansen, Christa Ringers, Francisca Acuña-Hinrichsen, Subhra P Hui, Emilie W Olstad, Yan Ling Chong, Charlton Kang An Lim, Astha Gupta, Chee Peng Ng, Benedikt S Nilges, Nachiket D Kashikar, Dagmar Wachten, David Liebl, Kazu Kikuchi, Caghan Kizil, Emre Yaksi, Sudipto Roy, Nathalie Jurisch-Yaksi

  • Soluble adenylyl cyclase inhibition prevents human sperm functions essential for fertilization.

    Molecular human reproduction

    Authors: Melanie Balbach, Lubna Ghanem, Thomas Rossetti, Navpreet Kaur, Carla Ritagliati, Jacob Ferreira, Dario Krapf, Lis C Puga Molina, Celia Maria Santi, Jan Niklas Hansen, Dagmar Wachten, Makoto Fushimi, Peter T Meinke, Jochen Buck, Lonny R Levin

  • Nucleo-cytoplasmic shuttling of splicing factor SRSF1 is required for development and cilia function.

    eLife

    Authors: Fiona Haward, Magdalena M Maslon, Patricia L Yeyati, Nicolas Bellora, Jan N Hansen, Stuart Aitken, Jennifer Lawson, Alex von Kriegsheim, Dagmar Wachten, Pleasantine Mill, Ian R Adams, Javier F Caceres

  • Multifocal imaging for precise, label-free tracking of fast biological processes in 3D.

    Nature communications

    Authors: Jan N Hansen, An Gong, Dagmar Wachten, René Pascal, Alex Turpin, Jan F Jikeli, U Benjamin Kaupp, Luis Alvarez

  • Maintaining proteostasis under mechanical stress.

    EMBO reports

    Authors: Jörg Höhfeld, Thomas Benzing, Wilhelm Bloch, Dieter O Fürst, Sebastian Gehlert, Michael Hesse, Bernd Hoffmann, Thorsten Hoppe, Pitter F Huesgen, Maja Köhn, Waldemar Kolanus, Rudolf Merkel, Carien M Niessen, Wojciech Pokrzywa, Markus M Rinschen, Dagmar Wachten, Bettina Warscheid

  • The BBSome: a nexus controlling energy metabolism in the brain.

    The Journal of clinical investigation

    Authors: Sandra Blaess, Dagmar Wachten

  • Creld1 regulates myocardial development and function.

    Journal of molecular and cellular cardiology

    Authors: Vera Beckert, Sebastian Rassmann, Amir Hossein Kayvanjoo, Christina Klausen, Lorenzo Bonaguro, Dominik Simon Botermann, Melanie Krause, Kristin Moreth, Nadine Spielmann, Patricia da Silva-Buttkus, Helmut Fuchs, Valerie Gailus-Durner, Martin Hrabě de Angelis, Kristian Händler, Thomas Ulas, Anna C Aschenbrenner, Elvira Mass, Dagmar Wachten