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Publications

featured publications

  • Signal transduction in primary cilia - analyzing and manipulating GPCR and second messenger signaling.

    Pharmacology & therapeutics

    Authors: Dagmar Wachten, David U Mick

  • CiliaQ: a simple, open-source software for automated quantification of ciliary morphology and fluorescence in 2D, 3D, and 4D images.

    The European physical journal. E, Soft matter

    Authors: Jan Niklas Hansen, Sebastian Rassmann, Birthe Stüven, Nathalie Jurisch-Yaksi, Dagmar Wachten

  • Molecular Mechanism Underlying the Action of Glycoproteins on Mouse Sperm.

    Frontiers in cell and developmental biology

    Authors: Melanie Balbach, Hussein Hamzeh, Jan F Jikeli, Christoph Brenker, Christian Schiffer, Jan N Hansen, Pia Neugebauer, Christian Trötschel, Luca Jovine, Ling Han, Harvey M Florman, U Benjamin Kaupp, Timo Strünker, Dagmar Wachten

  • Cfap97d1 is important for flagellar axoneme maintenance and male mouse fertility.

    PLoS genetics

    Authors: Seiya Oura, Samina Kazi, Audrey Savolainen, Kaori Nozawa, Julio Castañeda, Zhifeng Yu, Haruhiko Miyata, Ryan M Matzuk, Jan N Hansen, Dagmar Wachten, Martin M Matzuk, Renata Prunskaite-Hyyryläinen

  • Nanobody-directed targeting of optogenetic tools to study signaling in the primary cilium.

    eLife

    Authors: Jan N Hansen, Fabian Kaiser, Christina Klausen, Birthe Stüven, Raymond Chong, Wolfgang Bönigk, David U Mick, Andreas Möglich, Nathalie Jurisch-Yaksi, Florian I Schmidt, Dagmar Wachten

  • Sphingolipids controlling ciliary and microvillar function.

    FEBS letters

    Authors: Fabian Kaiser, Mylene Huebecker, Dagmar Wachten

  • Rotational motion and rheotaxis of human sperm do not require functional CatSper channels and transmembrane Ca signaling.

    The EMBO journal

    Authors: Christian Schiffer, Steffen Rieger, Christoph Brenker, Samuel Young, Hussein Hamzeh, Dagmar Wachten, Frank Tüttelmann, Albrecht Röpke, U Benjamin Kaupp, Tao Wang, Alice Wagner, Claudia Krallmann, Sabine Kliesch, Carsten Fallnich, Timo Strünker

  • Elucidating cyclic AMP signaling in subcellular domains with optogenetic tools and fluorescent biosensors.

    Biochemical Society transactions

    Authors: Christina Klausen, Fabian Kaiser, Birthe Stüven, Jan N Hansen, Dagmar Wachten

  • Primary Cilia Signaling Promotes Axonal Tract Development and Is Disrupted in Joubert Syndrome-Related Disorders Models.

    Developmental cell

    Authors: Jiami Guo, James M Otis, Sarah K Suciu, Christy Catalano, Lei Xing, Sandii Constable, Dagmar Wachten, Stephanie Gupton, Janice Lee, Amelia Lee, Katherine H Blackley, Travis Ptacek, Jeremy M Simon, Stephane Schurmans, Garret D Stuber, Tamara Caspary, E S Anton

  • Revisiting and Redesigning Light-Activated Cyclic-Mononucleotide Phosphodiesterases.

    Journal of molecular biology

    Authors: Robert Stabel, Birthe Stüven, Jan Niklas Hansen, Heinz G Körschen, Dagmar Wachten, Andreas Möglich