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featured publications

  • Trained Immunity-Promoting Nanobiologic Therapy Suppresses Tumor Growth and Potentiates Checkpoint Inhibition.

    Cell

    Authors: Bram Priem, Mandy M T van Leent, Abraham J P Teunissen, Alexandros Marios Sofias, Vera P Mourits, Lisa Willemsen, Emma D Klein, Roderick S Oosterwijk, Anu E Meerwaldt, Jazz Munitz, Geoffrey Prévot, Anna Vera Verschuur, Sheqouia A Nauta, Esther M van Leeuwen, Elizabeth L Fisher, Karen A M de Jong, Yiming Zhao, Yohana C Toner, Georgios Soultanidis, Claudia Calcagno, Paul H H Bomans, Heiner Friedrich, Nico Sommerdijk, Thomas Reiner, Raphaël Duivenvoorden, Eva Zupančič, Julie S Di Martino, Ewelina Kluza, Mohammad Rashidian, Hidde L Ploegh, Rick M Dijkhuizen, Sjoerd Hak, Carlos Pérez-Medina, Jose Javier Bravo-Cordero, Menno P J de Winther, Leo A B Joosten, Andrea van Elsas, Zahi A Fayad, Alexander Rialdi, Denis Torre, Ernesto Guccione, Jordi Ochando, Mihai G Netea, Arjan W Griffioen, Willem J M Mulder

  • Innate Immune Training of Granulopoiesis Promotes Anti-tumor Activity.

    Cell

    Authors: Lydia Kalafati, Ioannis Kourtzelis, Jonas Schulte-Schrepping, Xiaofei Li, Aikaterini Hatzioannou, Tatyana Grinenko, Eman Hagag, Anupam Sinha, Canan Has, Sevina Dietz, Antonio Miguel de Jesus Domingues, Marina Nati, Sundary Sormendi, Ales Neuwirth, Antonios Chatzigeorgiou, Athanasios Ziogas, Mathias Lesche, Andreas Dahl, Ian Henry, Pallavi Subramanian, Ben Wielockx, Peter Murray, Peter Mirtschink, Kyoung-Jin Chung, Joachim L Schultze, Mihai G Netea, George Hajishengallis, Panayotis Verginis, Ioannis Mitroulis, Triantafyllos Chavakis

  • Roles of Trained Immunity in the Pathogenesis of Cholangiopathies: A Therapeutic Target.

    Hepatology (Baltimore, Md.)

    Authors: Chao Yan, Stephane Koda, Jing Wu, Bei-Bei Zhang, Qian Yu, Mihai G Netea, Ren-Xian Tang, Kui-Yang Zheng

  • Trained Immunity: Long-Term Adaptation in Innate Immune Responses.

    Arteriosclerosis, thrombosis, and vascular biology

    Authors: Helin Tercan, Niels P Riksen, Leo A B Joosten, Mihai G Netea, Siroon Bekkering

  • Subtle immunodeficiencies in nodular-bronchiectatic complex lung disease.

    ERJ open research

    Authors: Mariolina Bruno, Sanne M H Zweijpfenning, Jeske Verhoeven, Martin J Boeree, Mihai G Netea, Frank L van de Veerdonk, Jakko van Ingen, Wouter Hoefsloot

  • Genome-Wide Association Study Identifies Novel Colony Stimulating Factor 1 Locus Conferring Susceptibility to Cryptococcosis in Human Immunodeficiency Virus-Infected South Africans.

    Open forum infectious diseases

    Authors: Shichina Kannambath, Joseph N Jarvis, Rachel M Wake, Nicky Longley, Angela Loyse, Vicky Matzaraki, Raúl Aguirre-Gamboa, Cisca Wijmenga, Ronan Doyle, Maria Paximadis, Caroline T Tiemessen, Vinod Kumar, Alan Pittman, Graeme Meintjes, Thomas S Harrison, Mihai G Netea, Tihana Bicanic

  • Metformin enhances anti-mycobacterial responses by educating CD8+ T-cell immunometabolic circuits.

    Nature communications

    Authors: Julia Böhme, Nuria Martinez, Shamin Li, Andrea Lee, Mardiana Marzuki, Anteneh Mehari Tizazu, David Ackart, Jessica Haugen Frenkel, Alexandra Todd, Ekta Lachmandas, Josephine Lum, Foo Shihui, Tze Pin Ng, Bernett Lee, Anis Larbi, Mihai G Netea, Randall Basaraba, Reinout van Crevel, Evan Newell, Hardy Kornfeld, Amit Singhal

  • COVID-19-Associated Candidiasis (CAC): An Underestimated Complication in the Absence of Immunological Predispositions?

    Journal of fungi (Basel, Switzerland)

    Authors: Amir Arastehfar, Agostinho Carvalho, M Hong Nguyen, Mohammad Taghi Hedayati, Mihai G Netea, David S Perlin, Martin Hoenigl

  • Increased Plasma Heparanase Activity in COVID-19 Patients.

    Frontiers in immunology

    Authors: Baranca Buijsers, Cansu Yanginlar, Aline de Nooijer, Inge Grondman, Marissa L Maciej-Hulme, Inge Jonkman, Nico A F Janssen, Nils Rother, Mark de Graaf, Peter Pickkers, Matthijs Kox, Leo A B Joosten, Tom Nijenhuis, Mihai G Netea, Luuk Hilbrands, Frank L van de Veerdonk, Raphaël Duivenvoorden, Quirijn de Mast, Johan van der Vlag

  • Genetic and Microbial Associations to Plasma and Fecal Bile Acids in Obesity Relate to Plasma Lipids and Liver Fat Content.

    Cell reports

    Authors: Lianmin Chen, Inge C L van den Munckhof, Kiki Schraa, Rob Ter Horst, Martijn Koehorst, Martijn van Faassen, Claude van der Ley, Marwah Doestzada, Daria V Zhernakova, Alexander Kurilshikov, Vincent W Bloks, Albert K Groen, Niels P Riksen, Joost H W Rutten, Leo A B Joosten, Cisca Wijmenga, Alexandra Zhernakova, Mihai G Netea, Jingyuan Fu, Folkert Kuipers