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featured publications

  • A modular approach toward producing nanotherapeutics targeting the innate immune system.

    Science advances

    Authors: Mandy M T van Leent, Anu E Meerwaldt, Alexandre Berchouchi, Yohana C Toner, Marianne E Burnett, Emma D Klein, Anna Vera D Verschuur, Sheqouia A Nauta, Jazz Munitz, Geoffrey Prévot, Esther M van Leeuwen, Farideh Ordikhani, Vera P Mourits, Claudia Calcagno, Philip M Robson, George Soultanidis, Thomas Reiner, Rick R M Joosten, Heiner Friedrich, Joren C Madsen, Ewelina Kluza, Roy van der Meel, Leo A B Joosten, Mihai G Netea, Jordi Ochando, Zahi A Fayad, Carlos Pérez-Medina, Willem J M Mulder, Abraham J P Teunissen

  • Data of common and species-specific transcriptional host responses to pathogenic fungi.

    Data in brief

    Authors: Mariolina Bruno, Robter Horst, Marina Pekmezovic, Vinod Kumar, Yang Li, Mihai G Netea, Jean-Paul Latgé, Mark S Gresnigt, Frank L van de Veerdonk

  • Trained Immunity: Reprogramming Innate Immunity in Health and Disease.

    Annual review of immunology

    Authors: Siroon Bekkering, Jorge Domínguez-Andrés, Leo A B Joosten, Niels P Riksen, Mihai G Netea

  • Deadly COVID-19 among the elderly: Innate immune memory helping those most in need.

    Med (New York, N.Y.)

    Authors: Yahya Sohrabi, Holger Reinecke, Leo A B Joosten, Mihai G Netea

  • induction of trained immunity in adherent human monocytes.

    STAR protocols

    Authors: Jorge Domínguez-Andrés, Rob J W Arts, Siroon Bekkering, Harsh Bahrar, Bastiaan A Blok, L Charlotte J de Bree, Mariolina Bruno, Özlem Bulut, Priya A Debisarun, Helga Dijkstra, Jéssica Cristina Dos Santos, Anaísa V Ferreira, Daniela Flores-Gomez, Laszlo A Groh, Inge Grondman, Leonie Helder, Cor Jacobs, Liesbeth Jacobs, Trees Jansen, Gizem Kilic, Viola Klück, Valerie A C M Koeken, Heidi Lemmers, Simone J C F M Moorlag, Vera P Mourits, Jelmer H van Puffelen, Katrin Rabold, Rutger J Röring, Diletta Rosati, Helin Tercan, Julia van Tuijl, Jessica Quintin, Reinout van Crevel, Niels P Riksen, Leo A B Joosten, Mihai G Netea

  • IL-38 prevents induction of trained immunity by inhibition of mTOR signaling.

    Journal of leukocyte biology

    Authors: Dennis M de Graaf, Lisa U Teufel, Frank L van de Veerdonk, Leo A B Joosten, Mihai G Netea, Charles A Dinarello, Rob J W Arts

  • Systemic administration of β-glucan induces immune training in microglia.

    Journal of neuroinflammation

    Authors: Yang Heng, Xiaoming Zhang, Malte Borggrewe, Hilmar R J van Weering, Maaike L Brummer, Tjalling W Nijboer, Leo A B Joosten, Mihai G Netea, Erik W G M Boddeke, Jon D Laman, Bart J L Eggen

  • Lysine methyltransferase G9a is an important modulator of trained immunity.

    Clinical & translational immunology

    Authors: Vera P Mourits, Jelmer H van Puffelen, Boris Novakovic, Mariolina Bruno, Anaísa V Ferreira, Rob Jw Arts, Laszlo Groh, Tania O Crișan, Jelle Zwaag, Elisa Jentho, Matthijs Kox, Peter Pickkers, Frank L van de Veerdonk, Sebastian Weis, Egbert Oosterwijk, Sita H Vermeulen, Mihai G Netea, Leo Ab Joosten

  • BCG-induced non-specific effects on heterologous infectious disease in Ugandan neonates: an investigator-blind randomised controlled trial.

    The Lancet. Infectious diseases

    Authors: Sarah Prentice, Beatrice Nassanga, Emily L Webb, Florence Akello, Fred Kiwudhu, Hellen Akurut, Alison M Elliott, Rob J W Arts, Mihai G Netea, Hazel M Dockrell, Stephen Cose

  • Top publication

    Urban living in healthy Tanzanians is associated with an inflammatory status driven by dietary and metabolic changes.

    Nature immunology

    Authors: Godfrey S Temba, Vesla Kullaya, Tal Pecht, Blandina T Mmbaga, Anna C Aschenbrenner, Thomas Ulas, Gibson Kibiki, Furaha Lyamuya, Collins K Boahen, Vinod Kumar, Leo A B Joosten, Joachim L Schultze, Andre J van der Ven, Mihai G Netea, Quirijn de Mast