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featured publications

  • B. burgdorferi sensu lato-induced inhibition of antigen presentation is mediated by RIP1 signaling resulting in impaired functional T cell responses towards Candida albicans.

    Ticks and tick-borne diseases

    Authors: Michelle A E Brouwer, William Jones-Warner, Shafaque Rahman, Mariska Kerstholt, Anaísa V Ferreira, Marije Oosting, Guido J Hooiveld, Mihai G Netea, Leo A B Joosten

  • Overcoming immune dysfunction in the elderly: trained immunity as a novel approach.

    International immunology

    Authors: Ozlem Bulut, Gizem Kilic, Jorge Domínguez-Andrés, Mihai G Netea

  • Common gene variants within 3'-untranslated regions as modulators of multiple myeloma risk and survival.

    International journal of cancer

    Authors: Ombretta Melaiu, Angelica Macauda, Juan Sainz, Diego Calvetti, Maria Sole Facioni, Giuseppe Maccari, Rob Ter Horst, Mihai G Netea, Yang Li, Norbert Grząśko, Victor Moreno, Artur Jurczyszyn, Andrés Jerez, Marzena Watek, Judit Varkonyi, Ramon Garcia-Sanz, Marcin Kruszewski, Marek Dudziński, Katalin Kadar, Svend Erik Hove Jacobsen, Grzegorz Mazur, Vibeke Andersen, Malwina Rybicka, Daria Zawirska, Malgorzata Raźny, Jan Maciej Zaucha, Olga Ostrovsky, Elzbieta Iskierka-Jazdzewska, Rui Manuel Reis, Anna Stępień, Katia Beider, Arnon Nagler, Agnieszka Druzd-Sitek, Herlander Marques, Joaquin Martìnez-Lopez, Fabienne Lesueur, Hervé Avet-Loiseau, Annette Juul Vangsted, Malgorzata Krawczyk-Kulis, Aleksandra Butrym, Krzysztof Jamroziak, Charles Dumontet, Ulla Vogel, Marcin Rymko, Matteo Pelosini, Edyta Subocz, Gergely Szombath, Maria Eugenia Sarasquete, Roberto Silvestri, Federica Morani, Stefano Landi, Daniele Campa, Federico Canzian, Federica Gemignani

  • The Intersection of Epigenetics and Metabolism in Trained Immunity.

    Immunity

    Authors: Stephanie Fanucchi, Jorge Domínguez-Andrés, Leo A B Joosten, Mihai G Netea, Musa M Mhlanga

  • BCG Vaccination Induces Long-Term Functional Reprogramming of Human Neutrophils.

    Cell reports

    Authors: Simone J C F M Moorlag, Yessica Alina Rodriguez-Rosales, Joshua Gillard, Stephanie Fanucchi, Kate Theunissen, Boris Novakovic, Cynthia M de Bont, Yutaka Negishi, Ezio T Fok, Lydia Kalafati, Panayotis Verginis, Vera P Mourits, Valerie A C M Koeken, L Charlotte J de Bree, Ger J M Pruijn, Craig Fenwick, Reinout van Crevel, Leo A B Joosten, Irma Joosten, Hans Koenen, Musa M Mhlanga, Dimitri A Diavatopoulos, Triantafyllos Chavakis, Mihai G Netea

  • Cerebrospinal fluid IL-1β is elevated in tuberculous meningitis patients but not associated with mortality.

    Tuberculosis (Edinburgh, Scotland)

    Authors: Valerie A C M Koeken, Ahmad R Ganiem, Sofiati Dian, Rovina Ruslami, Lidya Chaidir, Mihai G Netea, Vinod Kumar, Bachti Alisjahbana, Reinout van Crevel, Arjan van Laarhoven

  • Hydroxychloroquine Inhibits the Trained Innate Immune Response to Interferons.

    Cell reports. Medicine

    Authors: Nils Rother, Cansu Yanginlar, Rik G H Lindeboom, Siroon Bekkering, Mandy M T van Leent, Baranca Buijsers, Inge Jonkman, Mark de Graaf, Marijke Baltissen, Lieke A Lamers, Niels P Riksen, Zahi A Fayad, Willem J M Mulder, Luuk B Hilbrands, Leo A B Joosten, Mihai G Netea, Michiel Vermeulen, Johan van der Vlag, Raphaël Duivenvoorden

  • Immune defects in patients with pulmonary disease without cystic fibrosis.

    ERJ open research

    Authors: Milou M F Schuurbiers, Mariolina Bruno, Sanne M H Zweijpfenning, Cecile Magis-Escurra, Martin Boeree, Mihai G Netea, Jakko van Ingen, Frank van de Veerdonk, Wouter Hoefsloot

  • Reprogramming of bone marrow myeloid progenitor cells in patients with severe coronary artery disease.

    eLife

    Authors: Marlies P Noz, Siroon Bekkering, Laszlo Groh, Tim Mj Nielen, Evert Jp Lamfers, Andreas Schlitzer, Saloua El Messaoudi, Niels van Royen, Erik Hjpg Huys, Frank Wmb Preijers, Esther Mm Smeets, Erik Hjg Aarntzen, Bowen Zhang, Yang Li, Manita Ej Bremmers, Walter Jfm van der Velden, Harry Dolstra, Leo Ab Joosten, Marc E Gomes, Mihai G Netea, Niels P Riksen

  • Top publication

    CRELD1 modulates homeostasis of the immune system in mice and humans.

    Nature immunology

    Authors: Lorenzo Bonaguro, Maren Köhne, Lisa Schmidleithner, Jonas Schulte-Schrepping, Stefanie Warnat-Herresthal, Arik Horne, Paul Kern, Patrick Günther, Rob Ter Horst, Martin Jaeger, Souad Rahmouni, Michel Georges, Christine S Falk, Yang Li, Elvira Mass, Marc Beyer, Leo A B Joosten, Mihai G Netea, Thomas Ulas, Joachim L Schultze, Anna C Aschenbrenner