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Publications

featured publications

  • Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape.

    Science (New York, N.Y.)

    Authors: Paul-Albert Koenig, Hrishikesh Das, Hejun Liu, Beate M Kümmerer, Florian N Gohr, Lea-Marie Jenster, Lisa D J Schiffelers, Yonas M Tesfamariam, Miki Uchima, Jennifer D Wuerth, Karl Gatterdam, Natalia Ruetalo, Maria H Christensen, Caroline I Fandrey, Sabine Normann, Jan M P Tödtmann, Steffen Pritzl, Leo Hanke, Jannik Boos, Meng Yuan, Xueyong Zhu, Jonathan L Schmid-Burgk, Hiroki Kato, Michael Schindler, Ian A Wilson, Matthias Geyer, Kerstin U Ludwig, B Martin Hällberg, Nicholas C Wu, Florian I Schmidt

  • The Nonstructural Protein NSs of Severe Fever with Thrombocytopenia Syndrome Virus Causes a Cytokine Storm through the Hyperactivation of NF-B.

    Molecular and cellular biology

    Authors: Jumana Khalil, Shintaro Yamada, Yuta Tsukamoto, Hiroto Abe, Masayuki Shimojima, Hiroki Kato, Takashi Fujita

  • Viral RNA recognition by LGP2 and MDA5, and activation of signaling through step-by-step conformational changes.

    Nucleic acids research

    Authors: Ivana Duic, Hisashi Tadakuma, Yoshie Harada, Ryo Yamaue, Katashi Deguchi, Yuki Suzuki, Shige H Yoshimura, Hiroki Kato, Kunio Takeyasu, Takashi Fujita

  • Influenza A virus NS1 optimises virus infectivity by enhancing genome packaging in a dsRNA-binding dependent manner.

    Virology journal

    Authors: Tim Wai Sha, Michaela Weber, Dacquin M Kasumba, Takeshi Noda, Masahiro Nakano, Hiroki Kato, Takashi Fujita

  • Priming Phosphorylation of TANK-Binding Kinase 1 by IκB Kinase β Is Essential in Toll-Like Receptor 3/4 Signaling.

    Molecular and cellular biology

    Authors: Hiroto Abe, Junko Satoh, Yutaro Shirasaka, Amane Kogure, Hiroki Kato, Shinji Ito, Takashi Fujita

  • Broad and systemic immune-modulating capacity of plant-derived dsRNA.

    International immunology

    Authors: Takara Hajake, Keita Matsuno, Dacquin M Kasumba, Haruka Oda, Moe Kobayashi, Nao Miyata, Madoka Shinji, Amane Kogure, Nodoka Kasajima, Masatoshi Okamatsu, Yoshihiro Sakoda, Hiroki Kato, Takashi Fujita

  • Identification of a new autoinhibitory domain of interferon-beta promoter stimulator-1 (IPS-1) for the tight regulation of oligomerization-driven signal activation.

    Biochemical and biophysical research communications

    Authors: Kiyohiro Takahasi, Koji Onomoto, Masataka Horiuchi, Hiroki Kato, Takashi Fujita, Mitsutoshi Yoneyama

  • Singleton-Merten Syndrome-like Skeletal Abnormalities in Mice with Constitutively Activated MDA5.

    Journal of immunology (Baltimore, Md. : 1950)

    Authors: Nobumasa Soda, Nobuhiro Sakai, Hiroki Kato, Masamichi Takami, Takashi Fujita

  • Fueling Type I Interferonopathies: Regulation and Function of Type I Interferon Antiviral Responses.

    Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research

    Authors: Chen Seng Ng, Hiroki Kato, Takashi Fujita

  • Screening for inhibitor of episomal DNA identified dicumarol as a hepatitis B virus inhibitor.

    PloS one

    Authors: Fumihiko Takeuchi, Sotaro Ikeda, Yuta Tsukamoto, Yoshikazu Iwasawa, Chen Qihao, Yukie Otakaki, Ouda Ryota, Wan-Ling Yao, Ryo Narita, Hijikata Makoto, Koichi Watashi, Takaji Wakita, Koh Takeuchi, Kazuaki Chayama, Amane Kogure, Hiroki Kato, Takashi Fujita