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featured publications

  • ENT1 inhibition enhances weight control and metabolic health in diet-induced obesity.

    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

    Authors: Lucas Chaible, Julie Preillon, Charlotte Philippart, Alizée Canevat, Laura Saerens, Dimitri Kondratow, Michael Deligny, Alexis Goffaux, Anne-Catherine Michaux, Marie-Claire Letellier, Nicolas Rosewick, David Carbonez, João Marchante, Francesco Strozzi, Erica Houthuys, Reece Marillier, Yvonne McGrath, Steven Van der Plas, Alexander Pfeifer, Julie Chesné

  • Purinergic adipocyte-macrophage crosstalk promotes degeneration of thermogenic brown adipose tissue.

    EMBO reports

    Authors: Michelle Y Jaeckstein, Alexander W Fischer, Björn Rissiek, Tobias Staehler, Markus Heine, Janina Behrens, Oliver Mann, Alexander Pfeifer, Tim Magnus, Christian Schlein, Anna Worthmann, Ludger Scheja, Friedrich Koch-Nolte, Joerg Heeren

  • The role of the IL-9‒NLRP3 axis in insulin resistance and adipose tissue inflammation during diet-induced obesity.

    Cellular & molecular immunology

    Authors: Marc P Hübner, Dennis de Coninck, Benjamin Lenz, Jayagopi Surendar, Marianne Koschel, Narcisse Victor Tchamatchoua Gandjui, Beng Amuam Andrew, Lucy Cho Nchang, Anita Obi Bate Ebob, Fanny Fri Fombad, Lisa Marie Springer, Lars Eppe, Frank A Schildberg, Samuel Wanji, Achim Hoerauf, Alexander Pfeifer, Indulekha Karunakaran

  • Publisher Correction: Cold-induced expression of a truncated adenylyl cyclase 3 acts as rheostat to brown fat function.

    Nature metabolism

    Authors: Sajjad Khani, Hande Topel, Ronja Kardinal, Ana Rita Tavanez, Ajeetha Josephrajan, Bjørk Ditlev Marcher Larsen, Michael James Gaudry, Philipp Leyendecker, Nadia Meincke Egedal, Aylin Seren Güller, Natasa Stanic, Phillip M M Ruppert, Isabella Gaziano, Nils Rouven Hansmeier, Elena Schmidt, Paul Klemm, Lara-Marie Vagliano, Rainer Stahl, Fraser Duthie, Jens-Henning Krause, Ana Bici, Christoph Andreas Engelhard, Sabrina Gohlke, Peter Frommolt, Thorsten Gnad, Alvaro Rada-Iglesias, Marta Pradas-Juni, Tim Julius Schulz, Frank Thomas Wunderlich, Alexander Pfeifer, Alexander Bartelt, Martin Jastroch, Dagmar Wachten, Jan-Wilhelm Kornfeld

  • The obesity pandemic and its impact on non-communicable disease burden.

    Pflugers Archiv : European journal of physiology

    Authors: Staffan Hildebrand, Alexander Pfeifer

  • Enhanced browning of adipose tissue by mirabegron-microspheres.

    Journal of controlled release : official journal of the Controlled Release Society

    Authors: Zheming Niu, Staffan Hildebrand, Sebastian Kappes, Mohamed Ehab Ali, Matthias Vogel, Mickel Mikhael, Danli Ran, Jan Kozak, Maria Wiedner, Dirk F Richter, Alf Lamprecht, Alexander Pfeifer

  • A molecular mechanism to diversify Ca signaling downstream of Gs protein-coupled receptors.

    Nature communications

    Authors: Julian Brands, Sergi Bravo, Lars Jürgenliemke, Lukas Grätz, Hannes Schihada, Fabian Frechen, Judith Alenfelder, Cy Pfeil, Paul Georg Ohse, Suzune Hiratsuka, Kouki Kawakami, Luna C Schmacke, Nina Heycke, Asuka Inoue, Gabriele König, Alexander Pfeifer, Dagmar Wachten, Gunnar Schulte, Torsten Steinmetzer, Val J Watts, Jesús Gomeza, Katharina Simon, Evi Kostenis

  • Pharmacological Gq inhibition induces strong pulmonary vasorelaxation and reverses pulmonary hypertension.

    EMBO molecular medicine

    Authors: Alexander Seidinger, Richard Roberts, Yan Bai, Marion Müller, Eva Pfeil, Michaela Matthey, Sarah Rieck, Judith Alenfelder, Gabriele M König, Alexander Pfeifer, Evi Kostenis, Anna Klinke, Bernd K Fleischmann, Daniela Wenzel

  • Differential cell type-specific function of the aryl hydrocarbon receptor and its repressor in diet-induced obesity and fibrosis.

    Molecular metabolism

    Authors: Frederike J Graelmann, Fabian Gondorf, Yasmin Majlesain, Birte Niemann, Katarina Klepac, Dominic Gosejacob, Marlene Gottschalk, Michelle Mayer, Irina Iriady, Philip Hatzfeld, Sophie K Lindenberg, Klaus Wunderling, Christoph Thiele, Zeinab Abdullah, Wei He, Karsten Hiller, Kristian Händler, Marc D Beyer, Thomas Ulas, Alexander Pfeifer, Charlotte Esser, Heike Weighardt, Irmgard Förster, Laia Reverte-Salisa

  • Top publication

    From Planning Stage Towards FAIR Data: A Practical Metadatasheet For Biomedical Scientists.

    Scientific data

    Authors: Lea Seep, Stephan Grein, Iva Splichalova, Danli Ran, Mickel Mikhael, Staffan Hildebrand, Mario Lauterbach, Karsten Hiller, Dalila Juliana Silva Ribeiro, Katharina Sieckmann, Ronja Kardinal, Hao Huang, Jiangyan Yu, Sebastian Kallabis, Janina Behrens, Andreas Till, Viktoriya Peeva, Akim Strohmeyer, Johanna Bruder, Tobias Blum, Ana Soriano-Arroquia, Dominik Tischer, Katharina Kuellmer, Yuanfang Li, Marc Beyer, Anne-Kathrin Gellner, Tobias Fromme, Henning Wackerhage, Martin Klingenspor, Wiebke K Fenske, Ludger Scheja, Felix Meissner, Andreas Schlitzer, Elvira Mass, Dagmar Wachten, Eicke Latz, Alexander Pfeifer, Jan Hasenauer