—After the preliminary publication on the preprint server medRxiv in May 2020, the study by scientists of the University of Bonn about the first coronavirus outbreak in Germany in the community of Gangelt has been published in the renowned scientific journal Nature Communications.
The study was already pre-published in May 2020 to meet the demand of scientific journals to make findings about COVID-19 available to science and the public as early as possible.
University of Bonn and ImmunoSensation² receive Henriette Herz-Price
—As one of eight universities in Germany, the University of Bonn was being awarded the Henriette Herz Prize by the Alexander von Humboldt Foundation. The university receives 125,000 euros for its concept for attracting internationally highly qualified young researchers.
Genetic disposition protects immune system from aging
—A genetic disposition that plays a role in the development of the heart in the embryo also appears to play a key role in the human immune system. This is shown by a recent study led by the University of Bonn. When the gene is not active enough, the immune defense system undergoes characteristic changes, causing it to lose its effectiveness. Doctors speak of an aging immune system, as a similar effect can often be observed in older people. In the medium term, the results may contribute to reduce these age-related losses. The study is published in the journal Nature Immunology. The gene…
—The University of Bonn Faculty of Medicine has awarded an honorary doctorate to renowned Australia-based immunologist Prof. Dr. Jacques Francis Albert Pierre Miller. The award ceremony was conducted online due to the corona pandemic, held as part of the Digital Cluster Science Days 2020 organized by the Cluster of Excellence ImmunoSensation.
Liver cells and western diet - regulating inflammation
—A high fat Western-style diet leads to hepatic steatosis that can progress to liver cancer. Christoph Thiele (LIMES Institute) from the Cluster of Excellence ImmunoSensation and his colleagues used click chemistry-based metabolic tracing and microscopy, to study the interaction between Kupffer cells and hepatocytes ex vivo. The mechanism that leads to the development of steatosis upon nutritional overload is complex and only partially understood. Their study was recently published in the Journal of Cells and could show that inflammatory signals from liver cells…
—A new wiki/ intranet for the Cluster of Excellence ImmunoSensation is now available for our member:
Thereby we use Confluence form the University of Bonn, where some Uni institutions (like the HRZ or Human Resources Development) with their areas can already be found.
In our new wiki / intranet information about our funding opportunities; Software and Hardware within the Cluster or important documentes for e.g. travel expenses can be found.
Access to Confluence is available to all employees with an Uni-ID.The access to the area for the cluster…
—A new consortium COVIMMUNE under the direction of Prof. Eicke Latz, speaker of the cluster of Excellence ImmunoSensation2 is being funded with around 2 Million Euros by the Federal Ministry of Education and Research (BMBF). The project "Understanding divergent host reactions to SARS-CoV-2 infections by precision immunology" (COVIMMUNE) brings together clinical researchers at the University Hospital Bonn who are involved in COVID-19 patient care with basic scientists with immunological expertise from the University of Bonn.
—Contrary to what has been generally assumed so far, a severe course of COVID-19 does not solely result in a strong immune reaction – rather, the immune response is caught in a continuous loop of activation and inhibition.
Experts from Charité - Universitätsmedizin Berlin, the University of Bonn, the German Center for Neurodegenerative Diseases (DZNE), the Helmholtz Centre for Infection Research (HZI) and the German Center for Infection Research (DZIF), along with colleagues from a nationwide research network, present these findings in "Cell"
—A new study by the University of Bonn and research institutions in Australia and Switzerland shows the strategies that tumor cells use to avoid being attacked by the imune system.The method developed for this work contributes to a better understanding of the "arms race" between immune defense and disease. The results could help to improve modern therapeutic approaches and were published in 'Immunity'.