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featured publications

  • The stem cell-specific protein TRIM71 inhibits maturation and activity of the pro-differentiation miRNA let-7 via two independent molecular mechanisms.

    RNA (New York, N.Y.)

    Authors: Lucia A Torres Fernández, Sibylle Mitschka, Thomas Ulas, Stefan Weise, Kilian Dahm, Matthias Becker, Kristian Händler, Marc Beyer, Julia Windhausen, Joachim L Schultze, Waldemar Kolanus

  • The gut microbiota is associated with the small intestinal paracellular permeability and the development of the immune system in healthy children during the first two years of life.

    Journal of translational medicine

    Authors: Mariusz Kaczmarczyk, Ulrike Löber, Karolina Adamek, Dagmara Węgrzyn, Karolina Skonieczna-Żydecka, Damian Malinowski, Igor Łoniewski, Lajos Markó, Thomas Ulas, Sofia K Forslund, Beata Łoniewska

  • S100A8/A9 is the first predictive marker for neonatal sepsis.

    Clinical and translational medicine

    Authors: Sabine Pirr, Louise Dauter, Thomas Vogl, Thomas Ulas, Bettina Bohnhorst, Johannes Roth, Dorothee Viemann

  • Creld1 regulates myocardial development and function.

    Journal of molecular and cellular cardiology

    Authors: Vera Beckert, Sebastian Rassmann, Amir Hossein Kayvanjoo, Christina Klausen, Lorenzo Bonaguro, Dominik Simon Botermann, Melanie Krause, Kristin Moreth, Nadine Spielmann, Patricia da Silva-Buttkus, Helmut Fuchs, Valerie Gailus-Durner, Martin Hrabě de Angelis, Kristian Händler, Thomas Ulas, Anna C Aschenbrenner, Elvira Mass, Dagmar Wachten

  • Top publication

    Urban living in healthy Tanzanians is associated with an inflammatory status driven by dietary and metabolic changes.

    Nature immunology

    Authors: Godfrey S Temba, Vesla Kullaya, Tal Pecht, Blandina T Mmbaga, Anna C Aschenbrenner, Thomas Ulas, Gibson Kibiki, Furaha Lyamuya, Collins K Boahen, Vinod Kumar, Leo A B Joosten, Joachim L Schultze, Andre J van der Ven, Mihai G Netea, Quirijn de Mast

  • Disease severity-specific neutrophil signatures in blood transcriptomes stratify COVID-19 patients.

    Genome medicine

    Authors: Anna C Aschenbrenner, Maria Mouktaroudi, Benjamin Krämer, Marie Oestreich, Nikolaos Antonakos, Melanie Nuesch-Germano, Konstantina Gkizeli, Lorenzo Bonaguro, Nico Reusch, Kevin Baßler, Maria Saridaki, Rainer Knoll, Tal Pecht, Theodore S Kapellos, Sarandia Doulou, Charlotte Kröger, Miriam Herbert, Lisa Holsten, Arik Horne, Ioanna D Gemünd, Nikoletta Rovina, Shobhit Agrawal, Kilian Dahm, Martina van Uelft, Anna Drews, Lena Lenkeit, Niklas Bruse, Jelle Gerretsen, Jannik Gierlich, Matthias Becker, Kristian Händler, Michael Kraut, Heidi Theis, Simachew Mengiste, Elena De Domenico, Jonas Schulte-Schrepping, Lea Seep, Jan Raabe, Christoph Hoffmeister, Michael ToVinh, Verena Keitel, Gereon Rieke, Valentina Talevi, Dirk Skowasch, N Ahmad Aziz, Peter Pickkers, Frank L van de Veerdonk, Mihai G Netea, Joachim L Schultze, Matthijs Kox, Monique M B Breteler, Jacob Nattermann, Antonia Koutsoukou, Evangelos J Giamarellos-Bourboulis, Thomas Ulas

  • Two populations of self-maintaining monocyte-independent macrophages exist in adult epididymis and testis.

    Proceedings of the National Academy of Sciences of the United States of America

    Authors: Ming Wang, Yalong Yang, Dilay Cansever, Yiming Wang, Crystal Kantores, Sébastien Messiaen, Delphine Moison, Gabriel Livera, Svetoslav Chakarov, Tobias Weinberger, Christopher Stremmel, Monika Fijak, Britta Klein, Christiane Pleuger, Zhexiong Lian, Wentao Ma, Qingzhi Liu, Kathrin Klee, Kristian Händler, Thomas Ulas, Andreas Schlitzer, Joachim L Schultze, Burkhard Becher, Melanie Greter, Zhaoyuan Liu, Florent Ginhoux, Slava Epelman, Christian Schulz, Andreas Meinhardt, Sudhanshu Bhushan

  • Top publication

    Longitudinal Multi-omics Analyses Identify Responses of Megakaryocytes, Erythroid Cells, and Plasmablasts as Hallmarks of Severe COVID-19.

    Immunity

    Authors: Joana P Bernardes, Neha Mishra, Florian Tran, Thomas Bahmer, Lena Best, Johanna I Blase, Dora Bordoni, Jeanette Franzenburg, Ulf Geisen, Jonathan Josephs-Spaulding, Philipp Köhler, Axel Künstner, Elisa Rosati, Anna C Aschenbrenner, Petra Bacher, Nathan Baran, Teide Boysen, Burkhard Brandt, Niklas Bruse, Jonathan Dörr, Andreas Dräger, Gunnar Elke, David Ellinghaus, Julia Fischer, Michael Forster, Andre Franke, Sören Franzenburg, Norbert Frey, Anette Friedrichs, Janina Fuß, Andreas Glück, Jacob Hamm, Finn Hinrichsen, Marc P Hoeppner, Simon Imm, Ralf Junker, Sina Kaiser, Ying H Kan, Rainer Knoll, Christoph Lange, Georg Laue, Clemens Lier, Matthias Lindner, Georgios Marinos, Robert Markewitz, Jacob Nattermann, Rainer Noth, Peter Pickkers, Klaus F Rabe, Alina Renz, Christoph Röcken, Jan Rupp, Annika Schaffarzyk, Alexander Scheffold, Jonas Schulte-Schrepping, Domagoj Schunk, Dirk Skowasch, Thomas Ulas, Klaus-Peter Wandinger, Michael Wittig, Johannes Zimmermann, Hauke Busch, Bimba F Hoyer, Christoph Kaleta, Jan Heyckendorf, Matthijs Kox, Jan Rybniker, Stefan Schreiber, Joachim L Schultze, Philip Rosenstiel

  • Top publication

    CRELD1 modulates homeostasis of the immune system in mice and humans.

    Nature immunology

    Authors: Lorenzo Bonaguro, Maren Köhne, Lisa Schmidleithner, Jonas Schulte-Schrepping, Stefanie Warnat-Herresthal, Arik Horne, Paul Kern, Patrick Günther, Rob Ter Horst, Martin Jaeger, Souad Rahmouni, Michel Georges, Christine S Falk, Yang Li, Elvira Mass, Marc Beyer, Leo A B Joosten, Mihai G Netea, Thomas Ulas, Joachim L Schultze, Anna C Aschenbrenner

  • A novel computational architecture for large-scale genomics.

    Nature biotechnology

    Authors: Matthias Becker, Hartmut Schultze, Kirk Bresniker, Sharad Singhal, Thomas Ulas, Joachim L Schultze