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featured publications

  • Scalable Prediction of Acute Myeloid Leukemia Using High-Dimensional Machine Learning and Blood Transcriptomics.

    iScience

    Authors: Stefanie Warnat-Herresthal, Konstantinos Perrakis, Bernd Taschler, Matthias Becker, Kevin Baßler, Marc Beyer, Patrick Günther, Jonas Schulte-Schrepping, Lea Seep, Kathrin Klee, Thomas Ulas, Torsten Haferlach, Sach Mukherjee, Joachim L Schultze

  • Modeling population heterogeneity from microbial communities to immune response in cells.

    Cellular and molecular life sciences : CMLS

    Authors: Tal Pecht, Anna C Aschenbrenner, Thomas Ulas, Antonella Succurro

  • Transcriptional Signature Derived from Murine Tumor-Associated Macrophages Correlates with Poor Outcome in Breast Cancer Patients.

    Cell reports

    Authors: Sander Tuit, Camilla Salvagno, Theodore S Kapellos, Cheei-Sing Hau, Lea Seep, Marie Oestreich, Kathrin Klee, Karin E de Visser, Thomas Ulas, Joachim L Schultze

  • Shiny-Seq: advanced guided transcriptome analysis.

    BMC research notes

    Authors: Zenitha Sundararajan, Rainer Knoll, Peter Hombach, Matthias Becker, Joachim L Schultze, Thomas Ulas

  • Interplay between thyroid cancer cells and macrophages: effects on IL-32 mediated cell death and thyroid cancer cell migration.

    Cellular oncology (Dordrecht)

    Authors: Yvette J E Sloot, Katrin Rabold, Thomas Ulas, Dennis M De Graaf, Bas Heinhuis, Kristian Händler, Joachim L Schultze, Mihai G Netea, Johannes W A Smit, Leo A B Joosten, Romana T Netea-Maier

  • Top publication

    Enzymatic Activity of HPGD in Treg Cells Suppresses Tconv Cells to Maintain Adipose Tissue Homeostasis and Prevent Metabolic Dysfunction.

    Immunity

    Authors: Lisa Schmidleithner, Yasser Thabet, Eva Schönfeld, Maren Köhne, Daniel Sommer, Zeinab Abdullah, Timothy Sadlon, Collins Osei-Sarpong, Kotha Subbaramaiah, Francesca Copperi, Kristian Haendler, Tamas Varga, Oliver Schanz, Svenja Bourry, Kevin Bassler, Wolfgang Krebs, Annika E Peters, Ann-Kathrin Baumgart, Maria Schneeweiss, Kathrin Klee, Susanne V Schmidt, Simone Nüssing, Jil Sander, Naganari Ohkura, Andreas Waha, Tim Sparwasser, F Thomas Wunderlich, Irmgard Förster, Thomas Ulas, Heike Weighardt, Shimon Sakaguchi, Alexander Pfeifer, Matthias Blüher, Andrew J Dannenberg, Nerea Ferreirós, Louis J Muglia, Claudia Wickenhauser, Simon C Barry, Joachim L Schultze, Marc Beyer

  • Membrane Cholesterol Efflux Drives Tumor-Associated Macrophage Reprogramming and Tumor Progression.

    Cell metabolism

    Authors: Pieter Goossens, Juan Rodriguez-Vita, Anders Etzerodt, Marion Masse, Olivia Rastoin, Victoire Gouirand, Thomas Ulas, Olympia Papantonopoulou, Miranda Van Eck, Nathalie Auphan-Anezin, Magali Bebien, Christophe Verthuy, Thien Phong Vu Manh, Martin Turner, Marc Dalod, Joachim L Schultze, Toby Lawrence

  • Therapeutic targeting of macrophages enhances chemotherapy efficacy by unleashing type I interferon response.

    Nature cell biology

    Authors: Camilla Salvagno, Metamia Ciampricotti, Sander Tuit, Cheei-Sing Hau, Antoinette van Weverwijk, Seth B Coffelt, Kelly Kersten, Kim Vrijland, Kevin Kos, Thomas Ulas, Ji-Ying Song, Chia-Huey Ooi, Dominik Rüttinger, Philippe A Cassier, Jos Jonkers, Joachim L Schultze, Carola H Ries, Karin E de Visser

  • Transcriptional profiling of human microglia reveals grey-white matter heterogeneity and multiple sclerosis-associated changes.

    Nature communications

    Authors: Marlijn van der Poel, Thomas Ulas, Mark R Mizee, Cheng-Chih Hsiao, Suzanne S M Miedema, Adelia, Karianne G Schuurman, Boy Helder, Sander W Tas, Joachim L Schultze, Jörg Hamann, Inge Huitinga

  • Expression of the Phosphatase Ppef2 Controls Survival and Function of CD8 Dendritic Cells.

    Frontiers in immunology

    Authors: Markus Zwick, Thomas Ulas, Yi-Li Cho, Christine Ried, Leonie Grosse, Charlotte Simon, Caroline Bernhard, Dirk H Busch, Joachim L Schultze, Veit R Buchholz, Susanne Stutte, Thomas Brocker