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Publications

featured publications

  • Mechanistic characterization and inhibition of PAD4-dependent NETosis following experimental neonatal hypoxic-ischemic brain injury.

    Experimental neurology

    Authors: Anna-Sophie Bremer, Maria Eugenia Bernis, Hannah Burkard, Elke Maes, Aimee S Wilson, Zhaoyang Xu, David H Rowitch, Waqar Hanif, Riki Kawaguchi, Thomas Ulas, Hemmen Sabir

  • Microglia activation by derepression of endogenous retroviruses drives inflammation and cellular senescence.

    Nature neuroscience

    Authors: Xin Yan, Christina Georgopoulou, Hang-Mao Lee, Ala Ahrari, Jenny Russ, Vijay Chandrasekar, Tim Ducksch, Giuliano Crispatzu, Valentina Talevi, Liang Qiao, Shobhit Agrawal, Sophie Crux, Andrew W Daman, Lena Wischhof, Miriam Stork, Margit Zweyer, Emma Dorotea Zanfi, Manon Chevallot-Beroux, Yunxiao Li, Elena De-Domenico, Dina Hüsson, Lorenzo Bonaguro, Yuanfang Li, Jonas Schulte-Schrepping, Qingyi Liang, Ketty Kessler, Dan Ehninger, Shahin Rafii, Jiankai Luo, Andreas Hermann, Annett Halle, Ying Liu, Elvira Mass, Melania Capasso, Hiroki Kato, Joachim L Schultze, Pierluigi Nicotera, Daniele Bano, Steven Zvi Josefowicz, Martin Fuhrmann, Thomas Ulas, Marc Beyer, Juntang Lin, Monique M B Breteler, N Ahmad Aziz, Paolo Salomoni

  • Kmt2c and Kmt2d histone methyltransferase deficiencies compromise macrophage function.

    Journal of leukocyte biology

    Authors: Burcu Al, Yerin Jung, Yubell P Alvarez, Alice Scarpa, Arslan Hamid, Younghoon Jang, Kai Ge, Elena de Domenico, Marc D Beyer, Heike Weighardt, Irmgard Förster, Thomas Ulas, Mihai G Netea, Katarzyna Placek

  • TGF-β and IL-2 differentially shape T follicular regulatory cell differentiation and stability in vitro.

    Cellular & molecular immunology

    Authors: Luisa Bach, Yinshui Chang, Olin Arteaga Transito, Mohammadamin Ghasemi, Lisa Maria Steinheuer, Teresa Steffen, Elena De Domenico, Thomas Ulas, F Thomas Wunderlich, Marc D Beyer, Kevin Thurley, Dirk Baumjohann

  • IgLON5 autoimmune antibodies activate Tau via neuronal hyperactivity.

    Science advances

    Authors: Bilge Askin, Cagla Kilic, César Cordero Gómez, Sophie Lan-Linh Duong, Alvaro Domingues-Baquero, Alexander Goihl, Karsten Nalbach, Joana Petushi, Pia Grundschöttel, Jessica Wagner, Valentine Thomas, Janne Lamberty, Emily Withers, Hanna Huber, Sabrina Huebschmann, Ekaterina Semenova, Paul Turko, Andrew G Newman, Lisa Diez, Marc Beyer, Elena De Domenico, Peter Körtvelyessy, Dirk Reinhold, Anja Schneider, Jonas J Neher, Thomas Ulas, Stefan F Lichtenthaler, Benjamin R Rost, Dietmar Schmitz, Harald Prüss, Susanne Wegmann

  • Semantic alignment of the German Human Genome-Phenome Archive metadata model in Europe's genomics field.

    Scientific data

    Authors: Karoline Mauer, Anandhi Iyappan, Simon Parker, Bilge Sürün, Galina Tremper, Paul Menges, Léon Kuchenbecker, Koray Kirli, Joachim L Schultze, Sven Nahnsen, Thomas Ulas

  • S100-alarmins, antenatal corticosteroids and the risk of late-onset sepsis in preterm infants: A prospective cohort study.

    PloS one

    Authors: Gloria Kessler, Thomas Ulas, Thomas Vogl, Johannes Roth, Fenja Albrecht, Gesine Hansen, Constantin S von Kaisenberg, Christoph Härtel, Bettina Bohnhorst, Dorothee Viemann, Sabine Pirr

  • TREM2 expression level is critical for microglial state, metabolic capacity and efficacy of TREM2 agonism.

    Nature communications

    Authors: Astrid F Feiten, Kilian Dahm, Kai Schlepckow, Bettina van Lengerich, Jung H Suh, Anika Reifschneider, Benedikt Wefers, Laura M Bartos, Karin Wind-Mark, Lis de Weerd, Thomas Ulas, Elena De-Domenico, Pia Grundschöttel, Stefan Paulusch, Benjamin Tast, Tamisa Honda, Stephan A Müller, Matthias Becker, Igor Khalin, Alessio Ricci, Arthur Liesz, Bettina Brunner, Claudia Krenner, Katrin Buschmann, Brigitte Nuscher, Lena Spieth, Niklas Junker, Stefan A Berghoff, Sonnet S Davis, Jonas J Neher, Wolfgang Wurst, Nikolaus Plesnila, Joseph W Lewcock, Mikael Simons, Stefan F Lichtenthaler, Gilbert Di Paolo, Matthias Brendel, Anja Capell, Kathryn M Monroe, Joachim L Schultze, Christian Haass

  • Deep immune profiling delineates hallmarks of disease heterogeneity in extrapulmonary tuberculosis.

    Nature communications

    Authors: Sebastian J Theobald, Kilian Dahm, Dinah Lange, Jannis B Spintge, Sandra Winter, Angela Klingmüller, Lisa Holsten, Alexander Simonis, Elena De Domenico, Henning Walczak, Martina van Uelft, Joachim L Schultze, Marc D Beyer, Thomas Ulas, Isabelle Suárez, Jan Rybniker

  • The effects of interleukin-6-receptor inhibition on monocytes in STEMI: a substudy of the ASSAIL-MI trial.

    EBioMedicine

    Authors: Camilla Huse, Sarah Louise Murphy, Kuan Yang, Nora Reka Balzer, Mathis K Stokke, Anne Kristine Anstensrud, Vigdis Bjerkeli, Thiago Rentz, Prabhash Kumar Jha, Hege Katrin Ugland, Annika E Michelsen, Thor Ueland, Sverre Holm, Ingvild Maria Tøllefsen, Bjørn Bendz, Ola Kleveland, Geir Øystein Andersen, Lars Gullestad, William E Louch, Sindre Woxholt, Liv Osnes, Kaspar Broch, Thomas Ulas, Pål Aukrust, Peter Libby, Bente Halvorsen, Tuva B Dahl