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featured publications

  • TGF-β and IL-2 differentially shape T follicular regulatory cell differentiation and stability in vitro.

    Cellular & molecular immunology

    Authors: Luisa Bach, Yinshui Chang, Olin Arteaga Transito, Mohammadamin Ghasemi, Lisa Maria Steinheuer, Teresa Steffen, Elena De Domenico, Thomas Ulas, F Thomas Wunderlich, Marc D Beyer, Kevin Thurley, Dirk Baumjohann

  • IgLON5 autoimmune antibodies activate Tau via neuronal hyperactivity.

    Science advances

    Authors: Bilge Askin, Cagla Kilic, César Cordero Gómez, Sophie Lan-Linh Duong, Alvaro Domingues-Baquero, Alexander Goihl, Karsten Nalbach, Joana Petushi, Pia Grundschöttel, Jessica Wagner, Valentine Thomas, Janne Lamberty, Emily Withers, Hanna Huber, Sabrina Huebschmann, Ekaterina Semenova, Paul Turko, Andrew G Newman, Lisa Diez, Marc Beyer, Elena De Domenico, Peter Körtvelyessy, Dirk Reinhold, Anja Schneider, Jonas J Neher, Thomas Ulas, Stefan F Lichtenthaler, Benjamin R Rost, Dietmar Schmitz, Harald Prüss, Susanne Wegmann

  • Semantic alignment of the German Human Genome-Phenome Archive metadata model in Europe's genomics field.

    Scientific data

    Authors: Karoline Mauer, Anandhi Iyappan, Simon Parker, Bilge Sürün, Galina Tremper, Paul Menges, Léon Kuchenbecker, Koray Kirli, Joachim L Schultze, Sven Nahnsen, Thomas Ulas

  • S100-alarmins, antenatal corticosteroids and the risk of late-onset sepsis in preterm infants: A prospective cohort study.

    PloS one

    Authors: Gloria Kessler, Thomas Ulas, Thomas Vogl, Johannes Roth, Fenja Albrecht, Gesine Hansen, Constantin S von Kaisenberg, Christoph Härtel, Bettina Bohnhorst, Dorothee Viemann, Sabine Pirr

  • TREM2 expression level is critical for microglial state, metabolic capacity and efficacy of TREM2 agonism.

    Nature communications

    Authors: Astrid F Feiten, Kilian Dahm, Kai Schlepckow, Bettina van Lengerich, Jung H Suh, Anika Reifschneider, Benedikt Wefers, Laura M Bartos, Karin Wind-Mark, Lis de Weerd, Thomas Ulas, Elena De-Domenico, Pia Grundschöttel, Stefan Paulusch, Benjamin Tast, Tamisa Honda, Stephan A Müller, Matthias Becker, Igor Khalin, Alessio Ricci, Arthur Liesz, Bettina Brunner, Claudia Krenner, Katrin Buschmann, Brigitte Nuscher, Lena Spieth, Niklas Junker, Stefan A Berghoff, Sonnet S Davis, Jonas J Neher, Wolfgang Wurst, Nikolaus Plesnila, Joseph W Lewcock, Mikael Simons, Stefan F Lichtenthaler, Gilbert Di Paolo, Matthias Brendel, Anja Capell, Kathryn M Monroe, Joachim L Schultze, Christian Haass

  • Deep immune profiling delineates hallmarks of disease heterogeneity in extrapulmonary tuberculosis.

    Nature communications

    Authors: Sebastian J Theobald, Kilian Dahm, Dinah Lange, Jannis B Spintge, Sandra Winter, Angela Klingmüller, Lisa Holsten, Alexander Simonis, Elena De Domenico, Henning Walczak, Martina van Uelft, Joachim L Schultze, Marc D Beyer, Thomas Ulas, Isabelle Suárez, Jan Rybniker

  • The effects of interleukin-6-receptor inhibition on monocytes in STEMI: a substudy of the ASSAIL-MI trial.

    EBioMedicine

    Authors: Camilla Huse, Sarah Louise Murphy, Kuan Yang, Nora Reka Balzer, Mathis K Stokke, Anne Kristine Anstensrud, Vigdis Bjerkeli, Thiago Rentz, Prabhash Kumar Jha, Hege Katrin Ugland, Annika E Michelsen, Thor Ueland, Sverre Holm, Ingvild Maria Tøllefsen, Bjørn Bendz, Ola Kleveland, Geir Øystein Andersen, Lars Gullestad, William E Louch, Sindre Woxholt, Liv Osnes, Kaspar Broch, Thomas Ulas, Pål Aukrust, Peter Libby, Bente Halvorsen, Tuva B Dahl

  • Immune and metabolic effects of African heritage diets versus Western diets in men: a randomized controlled trial.

    Nature medicine

    Authors: Godfrey S Temba, Tal Pecht, Vesla I Kullaya, Nadira Vadaq, Mary V Mosha, Thomas Ulas, Sneha Kanungo, Liesbeth van Emst, Lorenzo Bonaguro, Jonas Schulte-Schrepping, Elias Mafuru, Paolo Lionetti, Musa M Mhlanga, Andre J van der Ven, Duccio Cavalieri, Leo A B Joosten, Reginald A Kavishe, Blandina T Mmbaga, Joachim L Schultze, Mihai G Netea, Quirijn de Mast

  • Persistent epigenetic memory of SARS-CoV-2 mRNA vaccination in monocyte-derived macrophages.

    Molecular systems biology

    Authors: Alexander Simonis, Sebastian J Theobald, Anna E Koch, Ram Mummadavarapu, Julie M Mudler, Andromachi Pouikli, Ulrike Göbel, Richard Acton, Sandra Winter, Alexandra Albus, Dmitriy Holzmann, Marie-Christine Albert, Michael Hallek, Henning Walczak, Thomas Ulas, Manuel Koch, Peter Tessarz, Robert Hänsel-Hertsch, Jan Rybniker

  • Oxidative phosphorylation is a key feature of neonatal monocyte immunometabolism promoting myeloid differentiation after birth.

    Nature communications

    Authors: Greta Ehlers, Annika Marie Tödtmann, Lisa Holsten, Maike Willers, Julia Heckmann, Jennifer Schöning, Maximilian Richter, Anna Sophie Heinemann, Sabine Pirr, Alexander Heinz, Christian Dopfer, Kristian Händler, Matthias Becker, Johanna Büchel, Achim Wöckel, Constantin von Kaisenberg, Gesine Hansen, Karsten Hiller, Joachim L Schultze, Christoph Härtel, Wolfgang Kastenmüller, Martin Vaeth, Thomas Ulas, Dorothee Viemann