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Featured publications

  • Molecular mechanisms and treatment responses of pulmonary fibrosis in severe COVID-19.

    Respiratory research

    Authors: Emma J Kooistra, Kilian Dahm, Antonius E van Herwaarden, Jelle Gerretsen, Melanie Nuesch Germano, Karoline Mauer, Ruben L Smeets, Sjef van der Velde, Maarten J W van den Berg, Johannes G van der Hoeven, Anna C Aschenbrenner, Joachim L Schultze, Thomas Ulas, Matthijs Kox, Peter Pickkers

  • Identification of the novel FOXP3-dependent T cell transcription factor MEOX1 by high-dimensional analysis of human CD4 T cells.

    Frontiers in immunology

    Authors: Kevin Baßler, Lisa Schmidleithner, Mehrnoush Hadaddzadeh Shakiba, Tarek Elmzzahi, Maren Köhne, Stefan Floess, Rebekka Scholz, Naganari Ohkura, Timothy Sadlon, Kathrin Klee, Anna Neubauer, Shimon Sakaguchi, Simon C Barry, Jochen Huehn, Lorenzo Bonaguro, Thomas Ulas, Marc Beyer

  • Systemic alterations in neutrophils and their precursors in early-stage chronic obstructive pulmonary disease.

    Cell reports

    Authors: Theodore S Kapellos, Kevin Baßler, Wataru Fujii, Christina Nalkurthi, Anna C Schaar, Lorenzo Bonaguro, Tal Pecht, Izabela Galvao, Shobhit Agrawal, Adem Saglam, Erica Dudkin, Amit Frishberg, Elena de Domenico, Arik Horne, Chantal Donovan, Richard Y Kim, David Gallego-Ortega, Tessa E Gillett, Meshal Ansari, Jonas Schulte-Schrepping, Nina Offermann, Ignazio Antignano, Burcu Sivri, Wenying Lu, Mathew S Eapen, Martina van Uelft, Collins Osei-Sarpong, Maarten van den Berge, Hylke C Donker, Harry J M Groen, Sukhwinder S Sohal, Johanna Klein, Tina Schreiber, Andreas Feißt, Ali Önder Yildirim, Herbert B Schiller, Martijn C Nawijn, Matthias Becker, Kristian Händler, Marc Beyer, Melania Capasso, Thomas Ulas, Jan Hasenauer, Carmen Pizarro, Fabian J Theis, Philip M Hansbro, Dirk Skowasch, Joachim L Schultze

  • Circuit-selective cell-autonomous regulation of inhibition in pyramidal neurons by Ste20-like kinase.

    Cell reports

    Authors: Pedro Royero, Anne Quatraccioni, Rieke Früngel, Mariella Hurtado Silva, Arco Bast, Thomas Ulas, Marc Beyer, Thoralf Opitz, Joachim L Schultze, Mark E Graham, Marcel Oberlaender, Albert Becker, Susanne Schoch, Heinz Beck

  • BCL7A-containing SWI/SNF/BAF complexes modulate mitochondrial bioenergetics during neural progenitor differentiation.

    The EMBO journal

    Authors: Lena Wischhof, Hang-Mao Lee, Janine Tutas, Clemens Overkott, Eileen Tedt, Miriam Stork, Michael Peitz, Oliver Brüstle, Thomas Ulas, Kristian Händler, Joachim L Schultze, Dan Ehninger, Pierluigi Nicotera, Paolo Salomoni, Daniele Bano

  • hCoCena: horizontal integration and analysis of transcriptomics datasets.

    Bioinformatics (Oxford, England)

    Authors: Marie Oestreich, Lisa Holsten, Shobhit Agrawal, Kilian Dahm, Philipp Koch, Han Jin, Matthias Becker, Thomas Ulas

  • Human variation in population-wide gene expression data predicts gene perturbation phenotype.

    iScience

    Authors: Lorenzo Bonaguro, Jonas Schulte-Schrepping, Caterina Carraro, Laura L Sun, Benedikt Reiz, Ioanna Gemünd, Adem Saglam, Souad Rahmouni, Michel Georges, Peer Arts, Alexander Hoischen, Leo A B Joosten, Frank L van de Veerdonk, Mihai G Netea, Kristian Händler, Sach Mukherjee, Thomas Ulas, Joachim L Schultze, Anna C Aschenbrenner

  • A guide to systems-level immunomics.

    Nature immunology

    Authors: Lorenzo Bonaguro, Jonas Schulte-Schrepping, Thomas Ulas, Anna C Aschenbrenner, Marc Beyer, Joachim L Schultze

  • Decoding mechanism of action and sensitivity to drug candidates from integrated transcriptome and chromatin state.

    eLife

    Authors: Caterina Carraro, Lorenzo Bonaguro, Jonas Schulte-Schrepping, Arik Horne, Marie Oestreich, Stefanie Warnat-Herresthal, Tim Helbing, Michele De Franco, Kristian Haendler, Sach Mukherjee, Thomas Ulas, Valentina Gandin, Richard Goettlich, Anna C Aschenbrenner, Joachim L Schultze, Barbara Gatto

  • Alveolar macrophages in early stage COPD show functional deviations with properties of impaired immune activation.

    Frontiers in immunology

    Authors: Kevin Baßler, Wataru Fujii, Theodore S Kapellos, Erika Dudkin, Nico Reusch, Ari Horne, Benedikt Reiz, Malte D Luecken, Collins Osei-Sarpong, Stefanie Warnat-Herresthal, Lorenzo Bonaguro, Jonas Schulte-Schrepping, Allon Wagner, Patrick Günther, Carmen Pizarro, Tina Schreiber, Rainer Knoll, Lisa Holsten, Charlotte Kröger, Elena De Domenico, Matthias Becker, Kristian Händler, Christian T Wohnhaas, Florian Baumgartner, Meike Köhler, Heidi Theis, Michael Kraut, Marc H Wadsworth, Travis K Hughes, Humberto J Ferreira, Emily Hinkley, Ines H Kaltheuner, Matthias Geyer, Christoph Thiele, Alex K Shalek, Andreas Feißt, Daniel Thomas, Henning Dickten, Marc Beyer, Patrick Baum, Nir Yosef, Anna C Aschenbrenner, Thomas Ulas, Jan Hasenauer, Fabian J Theis, Dirk Skowasch, Joachim L Schultze