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featured publications

  • BCG Vaccination in Humans Elicits Trained Immunity via the Hematopoietic Progenitor Compartment.

    Cell host & microbe

    Authors: Branko Cirovic, L Charlotte J de Bree, Laszlo Groh, Bas A Blok, Joyce Chan, Walter J F M van der Velden, M E J Bremmers, Reinout van Crevel, Kristian Händler, Simone Picelli, Jonas Schulte-Schrepping, Kathrin Klee, Marije Oosting, Valerie A C M Koeken, Jakko van Ingen, Yang Li, Christine S Benn, Joachim L Schultze, Leo A B Joosten, Nigel Curtis, Mihai G Netea, Andreas Schlitzer

  • CD163 expression defines specific, IRF8-dependent, immune-modulatory macrophages in the bone marrow.

    The Journal of allergy and clinical immunology

    Authors: Lena Fischer-Riepe, Niklas Daber, Jonas Schulte-Schrepping, Bruna Caroline Véras De Carvalho, Antonella Russo, Michele Pohlen, Josephine Fischer, Achmet Imam Chasan, Marc Wolf, Thomas Ulas, Shirin Glander, Christian Schulz, Boris Skryabin, Andreas Wollbrink Dipl-Ing, Nadine Steingraeber, Christopher Stremmel, Megan Koehle, Florian Gärtner, Sabine Vettorazzi, Dirk Holzinger, Joachim Gross, Frank Rosenbauer, Monika Stoll, Silke Niemann, Jan Tuckermann, Joachim L Schultze, Johannes Roth, Katarzyna Barczyk-Kahlert

  • Tumor endothelial cell up-regulation of IDO1 is an immunosuppressive feed-back mechanism that reduces the response to CD40-stimulating immunotherapy.

    Oncoimmunology

    Authors: Maria Georganaki, Mohanraj Ramachandran, Sander Tuit, Nicolás Gonzalo Núñez, Alexandros Karampatzakis, Grammatiki Fotaki, Luuk van Hooren, Hua Huang, Roberta Lugano, Thomas Ulas, Aura Kaunisto, Eric C Holland, Peter Ellmark, Sara M Mangsbo, Joachim Schultze, Magnus Essand, Sonia Tugues, Anna Dimberg

  • Defining trained immunity and its role in health and disease.

    Nature reviews. Immunology

    Authors: Mihai G Netea, Jorge Domínguez-Andrés, Luis B Barreiro, Triantafyllos Chavakis, Maziar Divangahi, Elaine Fuchs, Leo A B Joosten, Jos W M van der Meer, Musa M Mhlanga, Willem J M Mulder, Niels P Riksen, Andreas Schlitzer, Joachim L Schultze, Christine Stabell Benn, Joseph C Sun, Ramnik J Xavier, Eicke Latz

  • Top publication

    Cxcr4 distinguishes HSC-derived monocytes from microglia and reveals monocyte immune responses to experimental stroke.

    Nature neuroscience

    Authors: Yves Werner, Elvira Mass, Praveen Ashok Kumar, Thomas Ulas, Kristian Händler, Arik Horne, Kathrin Klee, Amelie Lupp, Dagmar Schütz, Friederike Saaber, Christoph Redecker, Joachim L Schultze, Frederic Geissmann, Ralf Stumm

  • Differential Gene Expression in Circulating CD14 Monocytes Indicates the Prognosis of Critically Ill Patients with Sepsis.

    Journal of clinical medicine

    Authors: Anke Liepelt, Philipp Hohlstein, Hendrik Gussen, Jia Xue, Anna C Aschenbrenner, Thomas Ulas, Lukas Buendgens, Klaudia T Warzecha, Matthias Bartneck, Tom Luedde, Christian Trautwein, Joachim L Schultze, Alexander Koch, Frank Tacke

  • Scalable Prediction of Acute Myeloid Leukemia Using High-Dimensional Machine Learning and Blood Transcriptomics.

    iScience

    Authors: Stefanie Warnat-Herresthal, Konstantinos Perrakis, Bernd Taschler, Matthias Becker, Kevin Baßler, Marc Beyer, Patrick Günther, Jonas Schulte-Schrepping, Lea Seep, Kathrin Klee, Thomas Ulas, Torsten Haferlach, Sach Mukherjee, Joachim L Schultze

  • Specificity meets function.

    Nature immunology

    Authors: Joachim L Schultze

  • Aging Induces an Nlrp3 Inflammasome-Dependent Expansion of Adipose B Cells That Impairs Metabolic Homeostasis.

    Cell metabolism

    Authors: Christina D Camell, Patrick Günther, Aileen Lee, Emily L Goldberg, Olga Spadaro, Yun-Hee Youm, Andrzej Bartke, Gene B Hubbard, Yuji Ikeno, Nancy H Ruddle, Joachim Schultze, Vishwa Deep Dixit

  • Transcriptional Signature Derived from Murine Tumor-Associated Macrophages Correlates with Poor Outcome in Breast Cancer Patients.

    Cell reports

    Authors: Sander Tuit, Camilla Salvagno, Theodore S Kapellos, Cheei-Sing Hau, Lea Seep, Marie Oestreich, Kathrin Klee, Karin E de Visser, Thomas Ulas, Joachim L Schultze