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featured publications

  • Large-scale analysis of temporal gene expression variation in peripheral blood.

    Nature communications

    Authors: Neha Mishra, Franziska Kimmig, Doris Vandeputte, Valentina Talevi, Lindsey De Commer, Chloe Verspecht, Arnau Vich Vila, Julia S El-Sayed Moustafa, Lukasz Kreft, Alexander Botzki, Youssef El Darzi, Sebastian Proost, Lindsay Devolder, Dongmeng Wang, Joana P Bernardes, N Ahmad Aziz, Andre Franke, Stefan Schreiber, Emmanouil T Dermitzakis, Sara Vieira-Silva, Gwen Falony, Kerrin S Small, Monique M B Breteler, Joachim L Schultze, Jeroen Raes, Philip Rosenstiel

  • Enhanced TLR7-induced interferon responses in women living with HIV.

    Frontiers in immunology

    Authors: Alisa Huber, Nadira Vadaq, Albert L Groenendijk, Victoria Rios-Vazquez, Suzanne D E Ruijten, Rainer Knoll, Joost A H Martens, Adriana Navas, Vasiliki Matzaraki, Wilhelm A J W Vos, Marc J T Blaauw, Louise E van Eekeren, Maartje C P Jacobs-Cleophas, Anna C Aschenbrenner, Joachim L Schultze, Jan van Lunzen, Mihai G Netea, Andre J A M van der Ven, Leo A B Joosten, Jéssica C Dos Santos

  • Semantic alignment of the German Human Genome-Phenome Archive metadata model in Europe's genomics field.

    Scientific data

    Authors: Karoline Mauer, Anandhi Iyappan, Simon Parker, Bilge Sürün, Galina Tremper, Paul Menges, Léon Kuchenbecker, Koray Kirli, Joachim L Schultze, Sven Nahnsen, Thomas Ulas

  • Persistent viral control status is associated with enhanced innate immune responses in people with HIV-1.

    iScience

    Authors: Jéssica C Dos Santos, Albert L Groenendijk, Suzanne D E Ruijten, Rainer Knoll, Nadira Vadaq, Rob Ter Horst, Ezio T Fok, Wojciech Witkowski, Marc J T Blaauw, Louise E van Eekeren, Wilhelm A J W Vos, Maartje Cleophas-Jacobs, Stephan Reichl, Twan Otten, Joost H A Martens, Arnold van der Meer, Han Koninkx, Marien I de Jonge, Marc D Beyer, Jan van Lunzen, Leo A B Joosten, Christoph Bock, Casper Rokx, Annelies Verbon, Linos Vandekerckhove, Anna C Aschenbrenner, Joachim L Schultze, Vasiliki Matzaraki, Andre J A M van der Ven, Mihai G Netea

  • TREM2 expression level is critical for microglial state, metabolic capacity and efficacy of TREM2 agonism.

    Nature communications

    Authors: Astrid F Feiten, Kilian Dahm, Kai Schlepckow, Bettina van Lengerich, Jung H Suh, Anika Reifschneider, Benedikt Wefers, Laura M Bartos, Karin Wind-Mark, Lis de Weerd, Thomas Ulas, Elena De-Domenico, Pia Grundschöttel, Stefan Paulusch, Benjamin Tast, Tamisa Honda, Stephan A Müller, Matthias Becker, Igor Khalin, Alessio Ricci, Arthur Liesz, Bettina Brunner, Claudia Krenner, Katrin Buschmann, Brigitte Nuscher, Lena Spieth, Niklas Junker, Stefan A Berghoff, Sonnet S Davis, Jonas J Neher, Wolfgang Wurst, Nikolaus Plesnila, Joseph W Lewcock, Mikael Simons, Stefan F Lichtenthaler, Gilbert Di Paolo, Matthias Brendel, Anja Capell, Kathryn M Monroe, Joachim L Schultze, Christian Haass

  • Genetic contribution to severe COVID-19 in adults under 60 years without major comorbidities in the German National Pandemic Cohort Network (NAPKON).

    Human genomics

    Authors: Ayda Abolhassani, T Madhusankha Alawathurage, Axel Schmidt, Fabian Brand, Laura L Kilarski, Heidi Altmann, Edgar Dahl, Sandra Frank, Siri Göpel, Frank Hanses, Johannes Christian Hellmuth, Christian Herr, Achim J Kaasch, Robin Kobbe, Margarethe Justine Konik, Isabell Pink, Christoph Römmele, Jan Rupp, Christian S Scheer, Marc A Schneider, Christoph Stellbrink, Hans Christian Stubbe, Phil-Robin Tepasse, Andreas Teufel, István Vadász, Maria J G T Vehreschild, Martin Witzenrath, Gabriele Anton, Isabel Bröhl, Susanne Herold, Thomas Illig, Steffi Jiru-Hillmann, Peter Krawitz, Lazar Mitrov, Alexandra Philipsen, Sina M Pütz, Markus M Noethen, Peter Nuernberg, Jens-Peter Reese, Olaf Riess, Stefan Schreiber, Joachim Schultze, Fridolin Steinbeis, J Janne Vehreschild, Christian Wildberg, Kerstin U Ludwig, Eva C Schulte

  • Laser-Capture Microdissection Followed by ATAC-Seq.

    Methods in molecular biology (Clifton, N.J.)

    Authors: Celia L Hartmann, Joachim L Schultze, Marc D Beyer, Caterina Carraro

  • Deep immune profiling delineates hallmarks of disease heterogeneity in extrapulmonary tuberculosis.

    Nature communications

    Authors: Sebastian J Theobald, Kilian Dahm, Dinah Lange, Jannis B Spintge, Sandra Winter, Angela Klingmüller, Lisa Holsten, Alexander Simonis, Elena De Domenico, Henning Walczak, Martina van Uelft, Joachim L Schultze, Marc D Beyer, Thomas Ulas, Isabelle Suárez, Jan Rybniker

  • Correction: Validity of the test for attentional performance in neurological post-COVID condition.

    Scientific reports

    Authors: Susan Seibert, Irina Eckert, Catherine N Widmann, Taraneh Ebrahimi, Fabian Bösl, Christiana Franke, Harald Prüss, Joachim L Schultze, Gabor C Petzold, Omid Shirvani

  • Immune and metabolic effects of African heritage diets versus Western diets in men: a randomized controlled trial.

    Nature medicine

    Authors: Godfrey S Temba, Tal Pecht, Vesla I Kullaya, Nadira Vadaq, Mary V Mosha, Thomas Ulas, Sneha Kanungo, Liesbeth van Emst, Lorenzo Bonaguro, Jonas Schulte-Schrepping, Elias Mafuru, Paolo Lionetti, Musa M Mhlanga, Andre J van der Ven, Duccio Cavalieri, Leo A B Joosten, Reginald A Kavishe, Blandina T Mmbaga, Joachim L Schultze, Mihai G Netea, Quirijn de Mast