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featured publications

  • CD4 T cell calibration of antigen-presenting cells optimizes antiviral CD8 T cell immunity.

    Nature immunology

    Authors: Elise Gressier, Jonas Schulte-Schrepping, Lev Petrov, Sophia Brumhard, Paula Stubbemann, Anna Hiller, Benedikt Obermayer, Jasper Spitzer, Tomislav Kostevc, Paul G Whitney, Annabell Bachem, Alexandru Odainic, Carolien van de Sandt, Thi H O Nguyen, Thomas Ashhurst, Kayla Wilson, Clare V L Oates, Linden J Gearing, Tina Meischel, Katharina Hochheiser, Marie Greyer, Michele Clarke, Maike Kreutzenbeck, Sarah S Gabriel, Wolfgang Kastenmüller, Christian Kurts, Sarah L Londrigan, Axel Kallies, Katherine Kedzierska, Paul J Hertzog, Eicke Latz, Yu-Chen E Chen, Kristen J Radford, Michael Chopin, Jan Schroeder, Florian Kurth, Thomas Gebhardt, Leif E Sander, Birgit Sawitzki, Joachim L Schultze, Susanne V Schmidt, Sammy Bedoui

  • Parallel recovery of chromatin accessibility and gene expression dynamics from frozen human regulatory T cells.

    Scientific reports

    Authors: Ying Y Wong, Jessica E Harbison, Christopher M Hope, Batjargal Gundsambuu, Katherine A Brown, Soon W Wong, Cheryl Y Brown, Jennifer J Couper, Jimmy Breen, Ning Liu, Stephen M Pederson, Maren Köhne, Kathrin Klee, Joachim Schultze, Marc Beyer, Timothy Sadlon, Simon C Barry

  • Single-cell analysis reveals dynamics of human B cell differentiation and identifies novel B and antibody-secreting cell intermediates.

    eLife

    Authors: Niels J M Verstegen, Sabrina Pollastro, Peter-Paul A Unger, Casper Marsman, George Elias, Tineke Jorritsma, Marij Streutker, Kevin Bassler, Kristian Haendler, Theo Rispens, Joachim L Schultze, Anja Ten Brinke, Marc Beyer, S Marieke van Ham

  • Building Trust in Medical Use of Artificial Intelligence - The Swarm Learning Principle.

    Journal of CME

    Authors: Joachim L Schultze

  • The 2000HIV study: Design, multi-omics methods and participant characteristics.

    Frontiers in immunology

    Authors: Wilhelm A J W Vos, Albert L Groenendijk, Marc J T Blaauw, Louise E van Eekeren, Adriana Navas, Maartje C P Cleophas, Nadira Vadaq, Vasiliki Matzaraki, Jéssica C Dos Santos, Elise M G Meeder, Janeri Fröberg, Gert Weijers, Yue Zhang, Jingyuan Fu, Rob Ter Horst, Christoph Bock, Rainer Knoll, Anna C Aschenbrenner, Joachim Schultze, Linos Vanderkerckhove, Talent Hwandih, Elizabeth R Wonderlich, Sai V Vemula, Mike van der Kolk, Sterre C P de Vet, Willem L Blok, Kees Brinkman, Casper Rokx, Arnt F A Schellekens, Quirijn de Mast, Leo A B Joosten, Marvin A H Berrevoets, Janneke E Stalenhoef, Annelies Verbon, Jan van Lunzen, Mihai G Netea, Andre J A M van der Ven

  • Circuit-selective cell-autonomous regulation of inhibition in pyramidal neurons by Ste20-like kinase.

    Cell reports

    Authors: Pedro Royero, Anne Quatraccioni, Rieke Früngel, Mariella Hurtado Silva, Arco Bast, Thomas Ulas, Marc Beyer, Thoralf Opitz, Joachim L Schultze, Mark E Graham, Marcel Oberlaender, Albert Becker, Susanne Schoch, Heinz Beck

  • BCL7A-containing SWI/SNF/BAF complexes modulate mitochondrial bioenergetics during neural progenitor differentiation.

    The EMBO journal

    Authors: Lena Wischhof, Hang-Mao Lee, Janine Tutas, Clemens Overkott, Eileen Tedt, Miriam Stork, Michael Peitz, Oliver Brüstle, Thomas Ulas, Kristian Händler, Joachim L Schultze, Dan Ehninger, Pierluigi Nicotera, Paolo Salomoni, Daniele Bano

  • Human variation in population-wide gene expression data predicts gene perturbation phenotype.

    iScience

    Authors: Lorenzo Bonaguro, Jonas Schulte-Schrepping, Caterina Carraro, Laura L Sun, Benedikt Reiz, Ioanna Gemünd, Adem Saglam, Souad Rahmouni, Michel Georges, Peer Arts, Alexander Hoischen, Leo A B Joosten, Frank L van de Veerdonk, Mihai G Netea, Kristian Händler, Sach Mukherjee, Thomas Ulas, Joachim L Schultze, Anna C Aschenbrenner

  • Longitudinal multi-omics analysis identifies early blood-based predictors of anti-TNF therapy response in inflammatory bowel disease.

    Genome medicine

    Authors: Neha Mishra, Konrad Aden, Johanna I Blase, Nathan Baran, Dora Bordoni, Florian Tran, Claudio Conrad, Diana Avalos, Charlot Jaeckel, Michael Scherer, Signe B Sørensen, Silja H Overgaard, Berenice Schulte, Susanna Nikolaus, Guillaume Rey, Gilles Gasparoni, Paul A Lyons, Joachim L Schultze, Jörn Walter, Vibeke Andersen, Emmanouil T Dermitzakis, Stefan Schreiber, Philip Rosenstiel

  • A guide to systems-level immunomics.

    Nature immunology

    Authors: Lorenzo Bonaguro, Jonas Schulte-Schrepping, Thomas Ulas, Anna C Aschenbrenner, Marc Beyer, Joachim L Schultze