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featured publications

  • Top publication

    Transmission of trained immunity and heterologous resistance to infections across generations.

    Nature immunology

    Authors: Natalie Katzmarski, Jorge Domínguez-Andrés, Branko Cirovic, Georgios Renieris, Eleonora Ciarlo, Didier Le Roy, Konstantin Lepikhov, Kathrin Kattler, Gilles Gasparoni, Kristian Händler, Heidi Theis, Marc Beyer, Jos W M van der Meer, Leo A B Joosten, Jörn Walter, Joachim L Schultze, Thierry Roger, Evangelos J Giamarellos-Bourboulis, Andreas Schlitzer, Mihai G Netea

  • Creld2 function during unfolded protein response is essential for liver metabolism homeostasis.

    FASEB journal : official publication of the Federation of American Societies for Experimental Biology

    Authors: Paul Kern, Nora R Balzer, Nelli Blank, Cornelia Cygon, Klaus Wunderling, Franziska Bender, Alex Frolov, Jan-Peter Sowa, Lorenzo Bonaguro, Thomas Ulas, Mirka Homrich, Eva Kiermaier, Christoph Thiele, Joachim L Schultze, Ali Canbay, Reinhard Bauer, Elvira Mass

  • Alveolar macrophage transcriptomic profiling in COPD shows major lipid metabolism changes.

    ERJ open research

    Authors: Wataru Fujii, Theodore S Kapellos, Kevin Baßler, Kristian Händler, Lisa Holsten, Rainer Knoll, Stefanie Warnat-Herresthal, Marie Oestreich, Emily R Hinkley, Jan Hasenauer, Carmen Pizarro, Christoph Thiele, Anna C Aschenbrenner, Thomas Ulas, Dirk Skowasch, Joachim L Schultze

  • Top publication

    Early IFN-α signatures and persistent dysfunction are distinguishing features of NK cells in severe COVID-19.

    Immunity

    Authors: Benjamin Krämer, Rainer Knoll, Lorenzo Bonaguro, Michael ToVinh, Jan Raabe, Rosario Astaburuaga-García, Jonas Schulte-Schrepping, Kim Melanie Kaiser, Gereon J Rieke, Jenny Bischoff, Malte B Monin, Christoph Hoffmeister, Stefan Schlabe, Elena De Domenico, Nico Reusch, Kristian Händler, Gary Reynolds, Nils Blüthgen, Gudrun Hack, Claudia Finnemann, Hans D Nischalke, Christian P Strassburg, Emily Stephenson, Yapeng Su, Louis Gardner, Dan Yuan, Daniel Chen, Jason Goldman, Philipp Rosenstiel, Susanne V Schmidt, Eicke Latz, Kevin Hrusovsky, Andrew J Ball, Joe M Johnson, Paul-Albert Koenig, Florian I Schmidt, Muzlifah Haniffa, James R Heath, Beate M Kümmerer, Verena Keitel, Björn Jensen, Paula Stubbemann, Florian Kurth, Leif E Sander, Birgit Sawitzki, Anna C Aschenbrenner, Joachim L Schultze, Jacob Nattermann

  • Soluble mannose receptor induces proinflammatory macrophage activation and metaflammation.

    Proceedings of the National Academy of Sciences of the United States of America

    Authors: Maria Embgenbroich, Hendrik J P van der Zande, Leonie Hussaarts, Jonas Schulte-Schrepping, Leonard R Pelgrom, Noemí García-Tardón, Laura Schlautmann, Isabel Stoetzel, Kristian Händler, Joost M Lambooij, Anna Zawistowska-Deniziak, Lisa Hoving, Karin de Ruiter, Marjolein Wijngaarden, Hanno Pijl, Ko Willems van Dijk, Bart Everts, Vanessa van Harmelen, Maria Yazdanbakhsh, Joachim L Schultze, Bruno Guigas, Sven Burgdorf

  • De novo DNA methylation controls neuronal maturation during adult hippocampal neurogenesis.

    The EMBO journal

    Authors: Sara Zocher, Rupert W Overall, Gabriel Berdugo-Vega, Nicole Rund, Anne Karasinsky, Vijay S Adusumilli, Christina Steinhauer, Sina Scheibenstock, Kristian Händler, Joachim L Schultze, Federico Calegari, Gerd Kempermann

  • Monocytes and Macrophages in COVID-19.

    Frontiers in immunology

    Authors: Rainer Knoll, Joachim L Schultze, Jonas Schulte-Schrepping

  • Privacy considerations for sharing genomics data.

    EXCLI journal

    Authors: Marie Oestreich, Dingfan Chen, Joachim L Schultze, Mario Fritz, Matthias Becker

  • Top publication

    Swarm Learning for decentralized and confidential clinical machine learning.

    Nature

    Authors: Stefanie Warnat-Herresthal, Hartmut Schultze, Krishnaprasad Lingadahalli Shastry, Sathyanarayanan Manamohan, Saikat Mukherjee, Vishesh Garg, Ravi Sarveswara, Kristian Händler, Peter Pickkers, N Ahmad Aziz, Sofia Ktena, Florian Tran, Michael Bitzer, Stephan Ossowski, Nicolas Casadei, Christian Herr, Daniel Petersheim, Uta Behrends, Fabian Kern, Tobias Fehlmann, Philipp Schommers, Clara Lehmann, Max Augustin, Jan Rybniker, Janine Altmüller, Neha Mishra, Joana P Bernardes, Benjamin Krämer, Lorenzo Bonaguro, Jonas Schulte-Schrepping, Elena De Domenico, Christian Siever, Michael Kraut, Milind Desai, Bruno Monnet, Maria Saridaki, Charles Martin Siegel, Anna Drews, Melanie Nuesch-Germano, Heidi Theis, Jan Heyckendorf, Stefan Schreiber, Sarah Kim-Hellmuth, Jacob Nattermann, Dirk Skowasch, Ingo Kurth, Andreas Keller, Robert Bals, Peter Nürnberg, Olaf Rieß, Philip Rosenstiel, Mihai G Netea, Fabian Theis, Sach Mukherjee, Michael Backes, Anna C Aschenbrenner, Thomas Ulas, Monique M B Breteler, Evangelos J Giamarellos-Bourboulis, Matthijs Kox, Matthias Becker, Sorin Cheran, Michael S Woodacre, Eng Lim Goh, Joachim L Schultze

  • The stem cell-specific protein TRIM71 inhibits maturation and activity of the pro-differentiation miRNA let-7 via two independent molecular mechanisms.

    RNA (New York, N.Y.)

    Authors: Lucia A Torres Fernández, Sibylle Mitschka, Thomas Ulas, Stefan Weise, Kilian Dahm, Matthias Becker, Kristian Händler, Marc Beyer, Julia Windhausen, Joachim L Schultze, Waldemar Kolanus