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  • PLCG2 protective variant p.P522R modulates tau pathology and disease progression in patients with mild cognitive impairment.

    Acta neuropathologica

    Authors: Luca Kleineidam, Vincent Chouraki, Tomasz Próchnicki, Sven J van der Lee, Laura Madrid-Márquez, Holger Wagner-Thelen, Ilker Karaca, Leonie Weinhold, Steffen Wolfsgruber, Anne Boland, Pamela V Martino Adami, Piotr Lewczuk, Julius Popp, Frederic Brosseron, Iris E Jansen, Marc Hulsman, Johannes Kornhuber, Oliver Peters, Claudine Berr, Reinhard Heun, Lutz Frölich, Christophe Tzourio, Jean-François Dartigues, Michael Hüll, Ana Espinosa, Isabel Hernández, Itziar de Rojas, Adelina Orellana, Sergi Valero, Najada Stringa, Natasja M van Schoor, Martijn Huisman, Philip Scheltens, Eckart Rüther, Jean-Francois Deleuze, Jens Wiltfang, Lluis Tarraga, Matthias Schmid, Martin Scherer, Steffi Riedel-Heller, Michael T Heneka, Philippe Amouyel, Frank Jessen, Merce Boada, Wolfgang Maier, Anja Schneider, Antonio González-Pérez, Wiesje M van der Flier, Michael Wagner, Jean-Charles Lambert, Henne Holstege, Mª Eugenia Sáez, Eicke Latz, Agustin Ruiz, Alfredo Ramirez

  • Defining trained immunity and its role in health and disease.

    Nature reviews. Immunology

    Authors: Mihai G Netea, Jorge Domínguez-Andrés, Luis B Barreiro, Triantafyllos Chavakis, Maziar Divangahi, Elaine Fuchs, Leo A B Joosten, Jos W M van der Meer, Musa M Mhlanga, Willem J M Mulder, Niels P Riksen, Andreas Schlitzer, Joachim L Schultze, Christine Stabell Benn, Joseph C Sun, Ramnik J Xavier, Eicke Latz

  • Multicenter Alzheimer's and Parkinson's disease immune biomarker verification study.

    Alzheimer's & dementia : the journal of the Alzheimer's Association

    Authors: Frederic Brosseron, Carl-Christian Kolbe, Francesco Santarelli, Stephanie Carvalho, Anna Antonell, Sergio Castro-Gomez, Pawel Tacik, Aishwarya Alex Namasivayam, Graziella Mangone, Reinhard Schneider, Eicke Latz, Ullrich Wüllner, Per Svenningsson, Raquel Sánchez-Valle, José Luis Molinuevo, Jean-Christophe Corvol, Michael T Heneka

  • Toll-like Receptor Signaling Rewires Macrophage Metabolism and Promotes Histone Acetylation via ATP-Citrate Lyase.

    Immunity

    Authors: Mario A Lauterbach, Jasmin E Hanke, Magdalini Serefidou, Matthew S J Mangan, Carl-Christian Kolbe, Timo Hess, Maximilian Rothe, Romina Kaiser, Florian Hoss, Jan Gehlen, Gudrun Engels, Maike Kreutzenbeck, Susanne V Schmidt, Anette Christ, Axel Imhof, Karsten Hiller, Eicke Latz

  • Apolipoprotein C3 induces inflammation and organ damage by alternative inflammasome activation.

    Nature immunology

    Authors: Stephen Zewinger, Jochen Reiser, Vera Jankowski, Dalia Alansary, Eunsil Hahm, Sarah Triem, Mira Klug, Stefan J Schunk, David Schmit, Rafael Kramann, Christina Körbel, Emmanuel Ampofo, Matthias W Laschke, Simina-Ramona Selejan, Anna Paschen, Tobias Herter, Susanne Schuster, Günther Silbernagel, Martina Sester, Urban Sester, Gunter Aßmann, Robert Bals, Gerhard Kostner, Willi Jahnen-Dechent, Michael D Menger, Lucia Rohrer, Winfried März, Michael Böhm, Joachim Jankowski, Manfred Kopf, Eicke Latz, Barbara A Niemeyer, Danilo Fliser, Ulrich Laufs, Thimoteus Speer

  • Top publication

    NLRP3 inflammasome activation drives tau pathology.

    Nature

    Authors: Christina Ising, Carmen Venegas, Shuangshuang Zhang, Hannah Scheiblich, Susanne V Schmidt, Ana Vieira-Saecker, Stephanie Schwartz, Shadi Albasset, Róisín M McManus, Dario Tejera, Angelika Griep, Francesco Santarelli, Frederic Brosseron, Sabine Opitz, James Stunden, Maximilian Merten, Rakez Kayed, Douglas T Golenbock, David Blum, Eicke Latz, Luc Buée, Michael T Heneka

  • Western Diet and the Immune System: An Inflammatory Connection.

    Immunity

    Authors: Anette Christ, Mario Lauterbach, Eicke Latz

  • CD82 controls CpG-dependent TLR9 signaling.

    FASEB journal : official publication of the Federation of American Societies for Experimental Biology

    Authors: Nida S Khan, Daniel P Lukason, Marianela Feliu, Rebecca A Ward, Allison K Lord, Jennifer L Reedy, Zaida G Ramirez-Ortiz, Jenny M Tam, Pia V Kasperkovitz, Paige E Negoro, Tammy D Vyas, Shuying Xu, Melanie M Brinkmann, Mridu Acharaya, Katerina Artavanis-Tsakonas, Eva-Maria Frickel, Christine E Becker, Zeina Dagher, You-Me Kim, Eicke Latz, Hidde L Ploegh, Michael K Mansour, Cindy K Miranti, Stuart M Levitz, Jatin M Vyas

  • Systemic inflammation impairs microglial Aβ clearance through NLRP3 inflammasome.

    The EMBO journal

    Authors: Dario Tejera, Dilek Mercan, Juan M Sanchez-Caro, Mor Hanan, David Greenberg, Hermona Soreq, Eicke Latz, Douglas Golenbock, Michael T Heneka

  • Blocking Inflammasome Activation Caused by β-Amyloid Peptide (Aβ) and Islet Amyloid Polypeptide (IAPP) through an IAPP Mimic.

    ACS chemical neuroscience

    Authors: Maryam Aftabizadeh, Marianna Tatarek-Nossol, Erika Andreetto, Omar El Bounkari, Markus Kipp, Cordian Beyer, Eicke Latz, Jürgen Bernhagen, Aphrodite Kapurniotu