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Featured publications

  • STAT3 serine phosphorylation is required for TLR4 metabolic reprogramming and IL-1β expression.

    Nature communications

    Authors: Jesse J Balic, Hassan Albargy, Kevin Luu, Francis J Kirby, W Samantha N Jayasekara, Finbar Mansell, Daniel J Garama, Dominic De Nardo, Nikola Baschuk, Cynthia Louis, Fiachra Humphries, Katherine Fitzgerald, Eicke Latz, Daniel J Gough, Ashley Mansell

  • Crystal structure of the human NLRP9 pyrin domain suggests a distinct mode of inflammasome assembly.

    FEBS letters

    Authors: Michael Marleaux, Kanchan Anand, Eicke Latz, Matthias Geyer

  • The RNA-binding protein hnRNPU regulates the sorting of microRNA-30c-5p into large extracellular vesicles.

    Journal of extracellular vesicles

    Authors: Andreas Zietzer, Mohammed Rabiul Hosen, Han Wang, Philip Roger Goody, Marc Sylvester, Eicke Latz, Georg Nickenig, Nikos Werner, Felix Jansen

  • Jack of all trades inhibits inflammation (in sober people).

    Nature immunology

    Authors: Florian I Schmidt, Eicke Latz

  • Spatiotemporal proteomics uncovers cathepsin-dependent macrophage cell death during Salmonella infection.

    Nature microbiology

    Authors: Joel Selkrig, Nan Li, Annika Hausmann, Matthew S J Mangan, Matylda Zietek, André Mateus, Jacob Bobonis, Anna Sueki, Haruna Imamura, Bachir El Debs, Gianluca Sigismondo, Bogdan I Florea, Herman S Overkleeft, Nataša Kopitar-Jerala, Boris Turk, Pedro Beltrao, Mikhail M Savitski, Eicke Latz, Wolf-Dietrich Hardt, Jeroen Krijgsveld, Athanasios Typas

  • Immediate and long-term consequences of COVID-19 infections for the development of neurological disease.

    Alzheimer's research & therapy

    Authors: Michael T Heneka, Douglas Golenbock, Eicke Latz, Dave Morgan, Robert Brown

  • Enduring Changes in Neuronal Function upon Systemic Inflammation Are NLRP3 Inflammasome Dependent.

    The Journal of neuroscience : the official journal of the Society for Neuroscience

    Authors: Marianna M S Beyer, Niklas Lonnemann, Anita Remus, Eicke Latz, Michael T Heneka, Martin Korte

  • Platelets Fuel the Inflammasome Activation of Innate Immune Cells.

    Cell reports

    Authors: Verena Rolfes, Lucas Secchim Ribeiro, Ibrahim Hawwari, Lisa Böttcher, Nathalia Rosero, Salie Maasewerd, Marina Lima Silva Santos, Tomasz Próchnicki, Camila Meirelles de Souza Silva, Carlos Wagner de Souza Wanderley, Maximilian Rothe, Susanne V Schmidt, H James Stunden, Damien Bertheloot, Magali Noval Rivas, Cor Jesus Fontes, Luzia Helena Carvalho, Fernando Queiroz Cunha, Eicke Latz, Moshe Arditi, Bernardo Simoes Franklin

  • β-Amyloid Clustering around ASC Fibrils Boosts Its Toxicity in Microglia.

    Cell reports

    Authors: Lea L Friker, Hannah Scheiblich, Inga V Hochheiser, Rebecca Brinkschulte, Dietmar Riedel, Eicke Latz, Matthias Geyer, Michael T Heneka

  • PLCG2 protective variant p.P522R modulates tau pathology and disease progression in patients with mild cognitive impairment.

    Acta neuropathologica

    Authors: Luca Kleineidam, Vincent Chouraki, Tomasz Próchnicki, Sven J van der Lee, Laura Madrid-Márquez, Holger Wagner-Thelen, Ilker Karaca, Leonie Weinhold, Steffen Wolfsgruber, Anne Boland, Pamela V Martino Adami, Piotr Lewczuk, Julius Popp, Frederic Brosseron, Iris E Jansen, Marc Hulsman, Johannes Kornhuber, Oliver Peters, Claudine Berr, Reinhard Heun, Lutz Frölich, Christophe Tzourio, Jean-François Dartigues, Michael Hüll, Ana Espinosa, Isabel Hernández, Itziar de Rojas, Adelina Orellana, Sergi Valero, Najada Stringa, Natasja M van Schoor, Martijn Huisman, Philip Scheltens, Eckart Rüther, Jean-Francois Deleuze, Jens Wiltfang, Lluis Tarraga, Matthias Schmid, Martin Scherer, Steffi Riedel-Heller, Michael T Heneka, Philippe Amouyel, Frank Jessen, Merce Boada, Wolfgang Maier, Anja Schneider, Antonio González-Pérez, Wiesje M van der Flier, Michael Wagner, Jean-Charles Lambert, Henne Holstege, Mª Eugenia Sáez, Eicke Latz, Agustin Ruiz, Alfredo Ramirez