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  • Western lifestyle linked to maladaptive trained immunity.

    eLife

    Authors: Aurelia Josephine Merbecks, Christabel Mennicken, Dennis Marinus de Graaf, Kateryna Shkarina, Theresa Wagner, Eicke Latz

  • Cyclodextrin reduces cholesterol crystal uptake by circulating monocytes in patients undergoing coronary angiography.

    PloS one

    Authors: Nikola Lübbering, Alexander Krogmann, Felix Jansen, Eicke Latz, Georg Nickenig, Sebastian Zimmer

  • NLRP3-induced systemic inflammation controls the development of JAK2V617F mutant myeloproliferative neoplasms.

    Nature communications

    Authors: Ruth-Miriam Koerber, Calvin Krollmann, Kevin Cieslak, Elisabeth Tregel, Maria L Saenz, Tim H Brümmendorf, Steffen Koschmieder, Martin Griesshammer, Ines Gütgemann, Conny K Baldauf, Thomas Fischer, Peter Brossart, Carl Christian Kolbe, Eicke Latz, Dominik Wolf, Lino L Teichmann

  • Enhancing Tyro3 signalling ameliorates IL-1β production through STAT1 in Alzheimer's disease models.

    Journal of leukocyte biology

    Authors: Kishore Aravind Ravichandran, Frederic Brosseron, Róisín M McManus, Christina Ising, Simon Görgen, Susanne Schmidt, Fracesco Santarelli, Se Young Lee, Hyuncheol Jung, Won-Suk Chung, Chan Hyuk Kim, Agustin Ruiz Laza, Carmen Ruiz de Almodóvar, Alfredo Ramirez, Eicke Latz, Michael T Heneka

  • The expanding role of the NLRP3 inflammasome from periodic fevers to therapeutic targets.

    Nature immunology

    Authors: Alexander N R Weber, Róisín M McManus, Veit Hornung, Matthias Geyer, Jasmin B Kuemmerle-Deschner, Eicke Latz

  • Clonal haematopoiesis of indeterminate potential is associated with progression of aortic valve stenosis.

    European journal of heart failure

    Authors: Raúl Nicolas Jamin, Jasmin Shamekhi, Tobias Zeus, Victor Mauri, Muntadher Al Zaidi, Benedikt Bartsch, Ansgar Ackerschott, Georg Nickenig, Eicke Latz, Sebastian Zimmer, Baravan Al-Kassou

  • Neuroinflammation and immunometabolism in neurodegenerative diseases.

    Current opinion in neurology

    Authors: Neha Lonkar, Eicke Latz, Róisín M McManus

  • NLRP3-mediated glutaminolysis controls microglial phagocytosis to promote Alzheimer's disease progression.

    Immunity

    Authors: Róisín M McManus, Max P Komes, Angelika Griep, Francesco Santarelli, Stephanie Schwartz, Juan Ramón Perea, Johannes C M Schlachetzki, David S Bouvier, Michelle-Amirah Khalil, Mario A Lauterbach, Lea Heinemann, Titus Schlüter, Mehran Shaban Pour, Marta Lovotti, Rainer Stahl, Fraser Duthie, Juan F Rodríguez-Alcázar, Susanne V Schmidt, Jasper Spitzer, Peri Noori, Alberto Maillo, Andreas Boettcher, Brian Herron, John McConville, David Gomez-Cabrero, Jesper Tegnér, Christopher K Glass, Karsten Hiller, Eicke Latz, Michael T Heneka

  • RNase T2 deficiency promotes TLR13-dependent replenishment of tissue-protective Kupffer cells.

    The Journal of experimental medicine

    Authors: Ryota Sato, Kaiwen Liu, Takuma Shibata, Katsuaki Hoshino, Kiyoshi Yamaguchi, Toru Miyazaki, Ryosuke Hiranuma, Ryutaro Fukui, Yuji Motoi, Yuri Fukuda-Ohta, Yun Zhang, Tatjana Reuter, Yuko Ishida, Toshikazu Kondo, Tomoki Chiba, Hiroshi Asahara, Masato Taoka, Yoshio Yamauchi, Toshiaki Isobe, Tsuneyasu Kaisho, Yoichi Furukawa, Eicke Latz, Kohta Nakatani, Yoshihiro Izumi, Yunzhong Nie, Hideki Taniguchi, Kensuke Miyake

  • Litomosoides sigmodontis microfilariae-induced eosinophil ETosis is dependent on the canonical inflammasome pathway.

    Cell reports

    Authors: Alexandra Ehrens, Benjamin Lenz, Celia Nieto-Pérez, Eicke Latz, Florian I Schmidt, Achim Hoerauf, Marc P Hübner