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Publications

featured publications

  • Immune dyshomeostasis in lifestyle-associated diseases: a new paradigm for personalized medicine and prevention.

    Current opinion in immunology

    Authors: Peter Duewell, Andreas Diefenbach, Eicke Latz

  • Inflammasome adaptor ASC promotes sustained neuroinflammation and mild cognitive impairment in a closed-head injury model.

    The Journal of clinical investigation

    Authors: Tao Li, Sergio Castro-Gomez, Pablo Botella Lucena, Ana Vieira-Saecker, Stephanie Schwartz, Yingying Ding, Yushuang Deng, Maling Guo, Valentin Stein, Douglas T Golenbock, Eicke Latz, Michael T Heneka

  • Remission of type 2 diabetes depends on time since diagnosis and low-calorie diet composition: Results of a randomized controlled trial in individuals with overweight and obesity.

    Diabetes research and clinical practice

    Authors: Bettina Schuppelius, Elena Lalama, Jiudan Zhang, Kilian Ruether, Marta Csanalosi, Stefan Kabisch, Anette Christ, Eicke Latz, Nicolle Kraenkel, Olga Pivovarova-Ramich, Knut Mai, Andreas F H Pfeiffer

  • Western lifestyle linked to maladaptive trained immunity.

    eLife

    Authors: Aurelia Josephine Merbecks, Christabel Mennicken, Dennis Marinus de Graaf, Kateryna Shkarina, Theresa Wagner, Eicke Latz

  • Cyclodextrin reduces cholesterol crystal uptake by circulating monocytes in patients undergoing coronary angiography.

    PloS one

    Authors: Nikola Lübbering, Alexander Krogmann, Felix Jansen, Eicke Latz, Georg Nickenig, Sebastian Zimmer

  • NLRP3-induced systemic inflammation controls the development of JAK2V617F mutant myeloproliferative neoplasms.

    Nature communications

    Authors: Ruth-Miriam Koerber, Calvin Krollmann, Kevin Cieslak, Elisabeth Tregel, Maria L Saenz, Tim H Brümmendorf, Steffen Koschmieder, Martin Griesshammer, Ines Gütgemann, Conny K Baldauf, Thomas Fischer, Peter Brossart, Carl Christian Kolbe, Eicke Latz, Dominik Wolf, Lino L Teichmann

  • Enhancing Tyro3 signalling ameliorates IL-1β production through STAT1 in Alzheimer's disease models.

    Journal of leukocyte biology

    Authors: Kishore Aravind Ravichandran, Frederic Brosseron, Róisín M McManus, Christina Ising, Simon Görgen, Susanne Schmidt, Fracesco Santarelli, Se Young Lee, Hyuncheol Jung, Won-Suk Chung, Chan Hyuk Kim, Agustin Ruiz Laza, Carmen Ruiz de Almodóvar, Alfredo Ramirez, Eicke Latz, Michael T Heneka

  • The expanding role of the NLRP3 inflammasome from periodic fevers to therapeutic targets.

    Nature immunology

    Authors: Alexander N R Weber, Róisín M McManus, Veit Hornung, Matthias Geyer, Jasmin B Kuemmerle-Deschner, Eicke Latz

  • Clonal haematopoiesis of indeterminate potential is associated with progression of aortic valve stenosis.

    European journal of heart failure

    Authors: Raúl Nicolas Jamin, Jasmin Shamekhi, Tobias Zeus, Victor Mauri, Muntadher Al Zaidi, Benedikt Bartsch, Ansgar Ackerschott, Georg Nickenig, Eicke Latz, Sebastian Zimmer, Baravan Al-Kassou

  • Neuroinflammation and immunometabolism in neurodegenerative diseases.

    Current opinion in neurology

    Authors: Neha Lonkar, Eicke Latz, Róisín M McManus