Skip to main content

Publications

Featured publications
  • Serum IL-6, sAXL, and YKL-40 as systemic correlates of reduced brain structure and function in Alzheimer's disease: results from the DELCODE study.

    Alzheimer's research & therapy

    Authors: Frederic Brosseron, Anne Maass, Luca Kleineidam, Kishore Aravind Ravichandran, Carl-Christian Kolbe, Steffen Wolfsgruber, Francesco Santarelli, Lisa M Häsler, Róisín McManus, Christina Ising, Sandra Röske, Oliver Peters, Nicoleta-Carmen Cosma, Luisa-Sophie Schneider, Xiao Wang, Josef Priller, Eike J Spruth, Slawek Altenstein, Anja Schneider, Klaus Fliessbach, Jens Wiltfang, Björn H Schott, Katharina Buerger, Daniel Janowitz, Martin Dichgans, Robert Perneczky, Boris-Stephan Rauchmann, Stefan Teipel, Ingo Kilimann, Doreen Görß, Christoph Laske, Matthias H Munk, Emrah Düzel, Renat Yakupow, Laura Dobisch, Coraline D Metzger, Wenzel Glanz, Michael Ewers, Peter Dechent, John Dylan Haynes, Klaus Scheffler, Nina Roy, Ayda Rostamzadeh, Annika Spottke, Alfredo Ramirez, David Mengel, Matthis Synofzik, Mathias Jucker, Eicke Latz, Frank Jessen, Michael Wagner, Michael T Heneka

    View this publication
  • Transcriptional licensing is required for Pyrin inflammasome activation in human macrophages and bypassed by mutations causing familial Mediterranean fever.

    PLoS biology

    Authors: Matthew S J Mangan, Friederike Gorki, Karoline Krause, Alexander Heinz, Anne Pankow, Thomas Ebert, Dieter Jahn, Karsten Hiller, Veit Hornung, Marcus Maurer, Florian I Schmidt, Ralf Gerhard, Eicke Latz

    View this publication
  • ATP-binding and hydrolysis of human NLRP3.

    Communications biology

    Authors: Rebecca Brinkschulte, David M Fußhöller, Florian Hoss, Juan F Rodríguez-Alcázar, Mario A Lauterbach, Carl-Christian Kolbe, Melanie Rauen, Semra Ince, Christian Herrmann, Eicke Latz, Matthias Geyer

    View this publication
  • Publication categories: Top publication

    P38 kinases mediate NLRP1 inflammasome activation after ribotoxic stress response and virus infection.

    The Journal of experimental medicine

    Authors: Lea-Marie Jenster, Karl-Elmar Lange, Sabine Normann, Anja vom Hemdt, Jennifer D Wuerth, Lisa D J Schiffelers, Yonas M Tesfamariam, Florian N Gohr, Laura Klein, Ines H Kaltheuner, Stefan Ebner, Dorothee J Lapp, Jacob Mayer, Jonas Moecking, Hidde L Ploegh, Eicke Latz, Felix Meissner, Matthias Geyer, Beate M Kümmerer, Florian I Schmidt

    View this publication
  • How location and cellular signaling combine to activate the NLRP3 inflammasome.

    Cellular & molecular immunology

    Authors: Anil Akbal, Alesja Dernst, Marta Lovotti, Matthew S J Mangan, Róisín M McManus, Eicke Latz

    View this publication
  • Circulating MicroRNA-122-5p Is Associated With a Lack of Improvement in Left Ventricular Function After Transcatheter Aortic Valve Replacement and Regulates Viability of Cardiomyocytes Through Extracellular Vesicles.

    Circulation

    Authors: Mohammed Rabiul Hosen, Philip Roger Goody, Andreas Zietzer, Xu Xiang, Sven Thomas Niepmann, Alexander Sedaghat, Vedat Tiyerili, Ramesh Chennupati, Joseph B Moore, Reinier A Boon, Shizuka Uchida, Jan-Malte Sinning, Sebastian Zimmer, Eicke Latz, Nikos Werner, Georg Nickenig, Felix Jansen

    View this publication
  • Imbalanced gut microbiota fuels hepatocellular carcinoma development by shaping the hepatic inflammatory microenvironment.

    Nature communications

    Authors: Kai Markus Schneider, Antje Mohs, Wenfang Gui, Eric J C Galvez, Lena Susanna Candels, Lisa Hoenicke, Uthayakumar Muthukumarasamy, Christian H Holland, Carsten Elfers, Konrad Kilic, Carolin Victoria Schneider, Robert Schierwagen, Pavel Strnad, Theresa H Wirtz, Hanns-Ulrich Marschall, Eicke Latz, Benjamin Lelouvier, Julio Saez-Rodriguez, Willem de Vos, Till Strowig, Jonel Trebicka, Christian Trautwein

    View this publication
  • Mesaconate is synthesized from itaconate and exerts immunomodulatory effects in macrophages.

    Nature metabolism

    Authors: Wei He, Antonia Henne, Mario Lauterbach, Eike Geißmar, Fabian Nikolka, Celia Kho, Alexander Heinz, Catherine Dostert, Melanie Grusdat, Thekla Cordes, Janika Härm, Oliver Goldmann, Anouk Ewen, Charlène Verschueren, Julia Blay-Cadanet, Robert Geffers, Hendrikus Garritsen, Manfred Kneiling, Christian K Holm, Christian M Metallo, Eva Medina, Zeinab Abdullah, Eicke Latz, Dirk Brenner, Karsten Hiller

    View this publication
  • Immune response in COVID-19: what is next?

    Cell death and differentiation

    Authors: Qing Li, Ying Wang, Qiang Sun, Jasmin Knopf, Martin Herrmann, Liangyu Lin, Jingting Jiang, Changshun Shao, Peishan Li, Xiaozhou He, Fei Hua, Zubiao Niu, Chaobing Ma, Yichao Zhu, Giuseppe Ippolito, Mauro Piacentini, Jerome Estaquier, Sonia Melino, Felix Daniel Weiss, Emanuele Andreano, Eicke Latz, Joachim L Schultze, Rino Rappuoli, Alberto Mantovani, Tak Wah Mak, Gerry Melino, Yufang Shi

    View this publication
  • Natural Killer Cell-Mediated Antibody-Dependent Cellular Cytotoxicity Against SARS-CoV-2 After Natural Infection Is More Potent Than After Vaccination.

    The Journal of infectious diseases

    Authors: Gereon J Rieke, Kathrin van Bremen, Jenny Bischoff, Michael ToVinh, Malte B Monin, Stefan Schlabe, Jan Raabe, Kim M Kaiser, Claudia Finnemann, Alexandru Odainic, Anushka Kudaliyanage, Eicke Latz, Christian P Strassburg, Christoph Boesecke, Susanne V Schmidt, Benjamin Krämer, Jürgen K Rockstroh, Jacob Nattermann

    View this publication