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  • Intestinal Dysbiosis Amplifies Acetaminophen-Induced Acute Liver Injury.

    Cellular and molecular gastroenterology and hepatology

    Authors: Kai Markus Schneider, Carsten Elfers, Ahmed Ghallab, Carolin Victoria Schneider, Eric J C Galvez, Antje Mohs, Wenfang Gui, Lena Susanna Candels, Theresa Hildegard Wirtz, Sebastian Zuehlke, Michael Spiteller, Maiju Myllys, Alain Roulet, Amirouche Ouzerdine, Benjamin Lelouvier, Konrad Kilic, Lijun Liao, Anika Nier, Eicke Latz, Ina Bergheim, Christoph A Thaiss, Jan G Hengstler, Till Strowig, Christian Trautwein

  • Interrelations of Alzheimer´s disease candidate biomarkers neurogranin, fatty acid-binding protein 3 and ferritin to neurodegeneration and neuroinflammation.

    Journal of neurochemistry

    Authors: Frederic Brosseron, Kilian Kleemann, Carl-Christian Kolbe, Francesco Santarelli, Sergio Castro-Gomez, Pawel Tacik, Eicke Latz, Frank Jessen, Michael T Heneka

  • Cholesterol crystals use complement to increase NLRP3 signaling pathways in coronary and carotid atherosclerosis.

    EBioMedicine

    Authors: Nathalie Niyonzima, Siril S Bakke, Ida Gregersen, Sverre Holm, Øystein Sandanger, Hilde L Orrem, Bjørnar Sporsheim, Liv Ryan, Xiang Yi Kong, Tuva Børresdatter Dahl, Mona Skjelland, Kirsten Krohg Sørensen, Anne Mari Rokstad, Arne Yndestad, Eicke Latz, Lars Gullestad, Geir Ø Andersen, Jan Kristian Damås, Pål Aukrust, Tom E Mollnes, Bente Halvorsen, Terje Espevik

  • 1-Deoxysphingolipids cause autophagosome and lysosome accumulation and trigger NLRP3 inflammasome activation.

    Autophagy

    Authors: Mario A Lauterbach, Victor Saavedra, Matthew S J Mangan, Anke Penno, Christoph Thiele, Eicke Latz, Lars Kuerschner

  • Metabolomic Profiling Reveals Distinct and Mutual Effects of Diet and Inflammation in Shaping Systemic Metabolism in Mice.

    Metabolites

    Authors: Mario A Lauterbach, Eicke Latz, Anette Christ

  • STAT3 serine phosphorylation is required for TLR4 metabolic reprogramming and IL-1β expression.

    Nature communications

    Authors: Jesse J Balic, Hassan Albargy, Kevin Luu, Francis J Kirby, W Samantha N Jayasekara, Finbar Mansell, Daniel J Garama, Dominic De Nardo, Nikola Baschuk, Cynthia Louis, Fiachra Humphries, Katherine Fitzgerald, Eicke Latz, Daniel J Gough, Ashley Mansell

  • Crystal structure of the human NLRP9 pyrin domain suggests a distinct mode of inflammasome assembly.

    FEBS letters

    Authors: Michael Marleaux, Kanchan Anand, Eicke Latz, Matthias Geyer

  • The RNA-binding protein hnRNPU regulates the sorting of microRNA-30c-5p into large extracellular vesicles.

    Journal of extracellular vesicles

    Authors: Andreas Zietzer, Mohammed Rabiul Hosen, Han Wang, Philip Roger Goody, Marc Sylvester, Eicke Latz, Georg Nickenig, Nikos Werner, Felix Jansen

  • Jack of all trades inhibits inflammation (in sober people).

    Nature immunology

    Authors: Florian I Schmidt, Eicke Latz

  • Spatiotemporal proteomics uncovers cathepsin-dependent macrophage cell death during Salmonella infection.

    Nature microbiology

    Authors: Joel Selkrig, Nan Li, Annika Hausmann, Matthew S J Mangan, Matylda Zietek, André Mateus, Jacob Bobonis, Anna Sueki, Haruna Imamura, Bachir El Debs, Gianluca Sigismondo, Bogdan I Florea, Herman S Overkleeft, Nataša Kopitar-Jerala, Boris Turk, Pedro Beltrao, Mikhail M Savitski, Eicke Latz, Wolf-Dietrich Hardt, Jeroen Krijgsveld, Athanasios Typas