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Publications

featured publications

  • Pre-treatment metastatic biopsy: a step towards precision oncology for urothelial cancer.

    Nature reviews. Urology

    Authors: Niklas Klümper, Alexander Cox, Gottfrid Sjödahl, Florian Roghmann, Christian Bolenz, Arndt Hartmann, Viktor Grünwald, Bishoy M Faltas, Michael Hölzel, Markus Eckstein

  • HLA-G expression associates with immune evasion muscle-invasive urothelial cancer and drives prognostic relevance.

    Frontiers in immunology

    Authors: Annalena Branz, Christian Matek, Fabienne Lange, Veronika Bahlinger, Niklas Klümper, Michael Hölzel, Pamela L Strissel, Reiner Strick, Danijel Sikic, Sven Wach, Helge Taubert, Bernd Wullich, Arndt Hartmann, Barbara Seliger, Markus Eckstein

  • Expression of the large amino acid transporter SLC7A5/LAT1 on immune cells is enhanced in primary sclerosing cholangitis-associated cholangiocarcinoma and correlates with poor prognosis in cholangiocarcinoma.

    Human pathology

    Authors: Vittorio Branchi, Racha Hosni, Lukas Kiwitz, Susanna Ng, Gemma van der Voort, Neila Bambi, Eileen Kleinfelder, Laura K Esser, Leona Dold, Bettina Langhans, Maria A Gonzalez-Carmona, Saskia Ting, Glen Kristiansen, Jörg C Kalff, Kevin Thurley, Michael Hölzel, Hanno Matthaei, Marieta I Toma

  • T lymphocyte recruitment to melanoma brain tumors depends on distinct venous vessels.

    Immunity

    Authors: Julia M Messmer, Calvin Thommek, Manuel Piechutta, Varun Venkataramani, Rebekka Wehner, Dana Westphal, Marc Schubert, Chanté D Mayer, Maike Effern, Anna S Berghoff, Daniel Hinze, Iris Helfrich, Dirk Schadendorf, Wolfgang Wick, Michael Hölzel, Matthia A Karreman, Frank Winkler

  • Transient MRI changes and neurological deterioration in glioblastoma upon SARS-CoV-2 infection.

    Journal of cancer research and clinical oncology

    Authors: Thomas Zeyen, Lea L Friker, Daniel Paech, Niklas Schaefer, Johannes Weller, Valentina Zschernack, Julian P Layer, Matthias Schneider, Anna-Laura Potthoff, Marit Bernhardt, Christine Sanders, Glen Kristiansen, Michael Hoelzel, Eleni Gkika, Alexander Radbruch, Torsten Pietsch, Ulrich Herrlinger, Christina Schaub

  • Melanoma Brain Metastases Patient-Derived Organoids: An In Vitro Platform for Drug Screening.

    Pharmaceutics

    Authors: Saif-Eldin Abedellatif, Racha Hosni, Andreas Waha, Gerrit H Gielen, Mohammed Banat, Motaz Hamed, Erdem Güresir, Anne Fröhlich, Judith Sirokay, Anna-Lena Wulf, Glen Kristiansen, Torsten Pietsch, Hartmut Vatter, Michael Hölzel, Matthias Schneider, Marieta Ioana Toma

  • Membranous expression of target protein is required for ADC response in urothelial cancer.

    European urology

    Authors: Niklas Klümper, Johannes Brägelmann, Veronika Bahlinger, Arndt Hartmann, Viktor Grünwald, Christoph Kuppe, Michael Hölzel, Markus Eckstein

  • Exploring membranous NECTIN-4 expression patterns and enfortumab vedotin response in prostate cancer.

    Journal of cellular and molecular medicine

    Authors: Richard Weiten, Marit Bernhardt, Max Niemann, Glen Kristiansen, Viktor Grünwald, Manuel Ritter, Michael Hölzel, Markus Eckstein, Abdullah Alajati, Niklas Klümper, Philipp Krausewitz

  • Preclinical evidence for the use of anti-Trop-2 antibody-drug conjugate Sacituzumab govitecan in cerebral metastasized castration-resistant prostate cancer.

    Cancer medicine

    Authors: Richard Weiten, Max Niemann, Eduard Below, Lea L Friker, Damian J Ralser, Marieta Toma, Glen Kristiansen, Oliver Hahn, Sabrina Zechel, Viktor Grünwald, Tobias Bald, Johannes Siewert, Torsten Pietsch, Manuel Ritter, Michael Hölzel, Markus Eckstein, Abdullah Alajati, Philipp Krausewitz, Niklas Klümper

  • L-RNA aptamer-based CXCL12 inhibition combined with radiotherapy in newly-diagnosed glioblastoma: dose escalation of the phase I/II GLORIA trial.

    Nature communications

    Authors: Frank A Giordano, Julian P Layer, Sonia Leonardelli, Lea L Friker, Roberta Turiello, Dillon Corvino, Thomas Zeyen, Christina Schaub, Wolf Müller, Elena Sperk, Leonard Christopher Schmeel, Katharina Sahm, Christoph Oster, Sied Kebir, Peter Hambsch, Torsten Pietsch, Sotirios Bisdas, Michael Platten, Martin Glas, Clemens Seidel, Ulrich Herrlinger, Michael Hölzel