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  • Type I Interferon Drives a Cellular State Inert to TCR-Stimulation and Could Impede Effective T-Cell Differentiation in Cancer.

    European journal of immunology

    Authors: Dillon Corvino, Martin Batstone, Brett G M Hughes, Tim Kempchen, Susanna S Ng, Nazhifah Salim, Franziska Schneppenheim, Denise Rommel, Ananthi Kumar, Sally Pearson, Jason Madore, Lambross T Koufariotis, Lisa Maria Steinheuer, Dilan Pathirana, Kevin Thurley, Michael Hölzel, Nicholas Borcherding, Matthias Braun, Tobias Bald

  • Pre-treatment metastatic biopsy: a step towards precision oncology for urothelial cancer.

    Nature reviews. Urology

    Authors: Niklas Klümper, Alexander Cox, Gottfrid Sjödahl, Florian Roghmann, Christian Bolenz, Arndt Hartmann, Viktor Grünwald, Bishoy M Faltas, Michael Hölzel, Markus Eckstein

  • HLA-G expression associates with immune evasion muscle-invasive urothelial cancer and drives prognostic relevance.

    Frontiers in immunology

    Authors: Annalena Branz, Christian Matek, Fabienne Lange, Veronika Bahlinger, Niklas Klümper, Michael Hölzel, Pamela L Strissel, Reiner Strick, Danijel Sikic, Sven Wach, Helge Taubert, Bernd Wullich, Arndt Hartmann, Barbara Seliger, Markus Eckstein

  • Expression of the large amino acid transporter SLC7A5/LAT1 on immune cells is enhanced in primary sclerosing cholangitis-associated cholangiocarcinoma and correlates with poor prognosis in cholangiocarcinoma.

    Human pathology

    Authors: Vittorio Branchi, Racha Hosni, Lukas Kiwitz, Susanna Ng, Gemma van der Voort, Neila Bambi, Eileen Kleinfelder, Laura K Esser, Leona Dold, Bettina Langhans, Maria A Gonzalez-Carmona, Saskia Ting, Glen Kristiansen, Jörg C Kalff, Kevin Thurley, Michael Hölzel, Hanno Matthaei, Marieta I Toma

  • T lymphocyte recruitment to melanoma brain tumors depends on distinct venous vessels.

    Immunity

    Authors: Julia M Messmer, Calvin Thommek, Manuel Piechutta, Varun Venkataramani, Rebekka Wehner, Dana Westphal, Marc Schubert, Chanté D Mayer, Maike Effern, Anna S Berghoff, Daniel Hinze, Iris Helfrich, Dirk Schadendorf, Wolfgang Wick, Michael Hölzel, Matthia A Karreman, Frank Winkler

  • Transient MRI changes and neurological deterioration in glioblastoma upon SARS-CoV-2 infection.

    Journal of cancer research and clinical oncology

    Authors: Thomas Zeyen, Lea L Friker, Daniel Paech, Niklas Schaefer, Johannes Weller, Valentina Zschernack, Julian P Layer, Matthias Schneider, Anna-Laura Potthoff, Marit Bernhardt, Christine Sanders, Glen Kristiansen, Michael Hoelzel, Eleni Gkika, Alexander Radbruch, Torsten Pietsch, Ulrich Herrlinger, Christina Schaub

  • Melanoma Brain Metastases Patient-Derived Organoids: An In Vitro Platform for Drug Screening.

    Pharmaceutics

    Authors: Saif-Eldin Abedellatif, Racha Hosni, Andreas Waha, Gerrit H Gielen, Mohammed Banat, Motaz Hamed, Erdem Güresir, Anne Fröhlich, Judith Sirokay, Anna-Lena Wulf, Glen Kristiansen, Torsten Pietsch, Hartmut Vatter, Michael Hölzel, Matthias Schneider, Marieta Ioana Toma

  • Membranous expression of target protein is required for ADC response in urothelial cancer.

    European urology

    Authors: Niklas Klümper, Johannes Brägelmann, Veronika Bahlinger, Arndt Hartmann, Viktor Grünwald, Christoph Kuppe, Michael Hölzel, Markus Eckstein

  • Exploring membranous NECTIN-4 expression patterns and enfortumab vedotin response in prostate cancer.

    Journal of cellular and molecular medicine

    Authors: Richard Weiten, Marit Bernhardt, Max Niemann, Glen Kristiansen, Viktor Grünwald, Manuel Ritter, Michael Hölzel, Markus Eckstein, Abdullah Alajati, Niklas Klümper, Philipp Krausewitz

  • Preclinical evidence for the use of anti-Trop-2 antibody-drug conjugate Sacituzumab govitecan in cerebral metastasized castration-resistant prostate cancer.

    Cancer medicine

    Authors: Richard Weiten, Max Niemann, Eduard Below, Lea L Friker, Damian J Ralser, Marieta Toma, Glen Kristiansen, Oliver Hahn, Sabrina Zechel, Viktor Grünwald, Tobias Bald, Johannes Siewert, Torsten Pietsch, Manuel Ritter, Michael Hölzel, Markus Eckstein, Abdullah Alajati, Philipp Krausewitz, Niklas Klümper