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Publications

Featured publications

  • Integrating On-Treatment Modified Glasgow Prognostic Score and Imaging to Predict Response and Outcomes in Metastatic Renal Cell Carcinoma.

    JAMA oncology

    Authors: Jonas Saal, Tobias Bald, Markus Eckstein, Damian J Ralser, Manuel Ritter, Peter Brossart, Viktor Grünwald, Michael Hölzel, Jörg Ellinger, Niklas Klümper

  • Re: First-in-Human Study of the Radioligand Ga-N188 Targeting Nectin-4 for PET/CT Imaging of Advanced Urothelial Carcinoma: Navigating Metastatic Urothelial Cancer with Nectin-4 PET/CT.

    European urology

    Authors: Niklas Klümper, Markus Eckstein, Michael Hölzel, Ken Herrmann, Boris Hadaschik, Viktor Grünwald

  • Risk assessment, surveillance, and nonpharmaceutical prevention of acute radiation dermatitis: results of a multicentric survey among the German-speaking radiation oncology community.

    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]

    Authors: Katharina Layer, Julian P Layer, Andrea R Glasmacher, Gustavo R Sarria, Alexander M C Böhner, Yonah L Layer, Cas S Dejonckheere, Stephan Garbe, Petra Feyer, Brigitta G Baumert, Anke Schendera, René Baumann, David Krug, Mümtaz A Köksal, David Koch, Davide Scafa, Christina Leitzen, Michael Hölzel, Frank A Giordano, Leonard Christopher Schmeel

  • Membranous NECTIN-4 Expression Frequently Decreases during Metastatic Spread of Urothelial Carcinoma and Is Associated with Enfortumab Vedotin Resistance.

    Clinical cancer research : an official journal of the American Association for Cancer Research

    Authors: Niklas Klümper, Damian J Ralser, Jörg Ellinger, Florian Roghmann, Julia Albrecht, Eduard Below, Abdullah Alajati, Danijel Sikic, Johannes Breyer, Christian Bolenz, Friedemann Zengerling, Philipp Erben, Kristina Schwamborn, Ralph M Wirtz, Thomas Horn, Dora Nagy, Marieta Toma, Glen Kristiansen, Thomas Büttner, Oliver Hahn, Viktor Grünwald, Christopher Darr, Eva Erne, Steffen Rausch, Jens Bedke, Katrin Schlack, Mahmoud Abbas, Stefanie Zschäbitz, Constantin Schwab, Alexander Mustea, Patrick Adam, Andreas Manseck, Bernd Wullich, Manuel Ritter, Arndt Hartmann, Jürgen Gschwend, Wilko Weichert, Franziska Erlmeier, Michael Hölzel, Markus Eckstein

  • Active Remodeling of Capillary Endothelium via Cancer Cell-Derived MMP9 Promotes Metastatic Brain Colonization.

    Cancer research

    Authors: Matthia A Karreman, Alexander T Bauer, Gergely Solecki, Anna S Berghoff, Chanté D Mayer, Katharina Frey, Nils Hebach, Manuel J Feinauer, Nicole L Schieber, Cedric Tehranian, Luc Mercier, Mahak Singhal, Varun Venkataramani, Marc C Schubert, Daniel Hinze, Michael Hölzel, Iris Helfrich, Dirk Schadendorf, Stefan W Schneider, Dana Westphal, Hellmut G Augustin, Jacky G Goetz, Yannick Schwab, Wolfgang Wick, Frank Winkler

  • Molecular Urothelial Tumor Cell Subtypes Remain Stable During Metastatic Evolution.

    European urology

    Authors: Alexander Cox, Niklas Klümper, Johannes Stein, Danijel Sikic, Johannes Breyer, Christian Bolenz, Florian Roghmann, Philipp Erben, Ralph M Wirtz, Bernd Wullich, Manuel Ritter, Michael Hölzel, Kristina Schwamborn, Thomas Horn, Jürgen Gschwend, Arndt Hartmann, Wilko Weichert, Franziska Erlmeier, Markus Eckstein

  • Glucocorticoid activation by HSD11B1 limits T cell-driven interferon signaling and response to PD-1 blockade in melanoma.

    Journal for immunotherapy of cancer

    Authors: Luiza Martins Nascentes Melo, Dayana Herrera-Rios, Daniel Hinze, Stefanie Löffek, Irem Oezel, Roberta Turiello, Juliane Klein, Sonia Leonardelli, Isa-Vanessa Westedt, Yahya Al-Matary, Sara Egea-Rodriguez, Alexandra Brenzel, Maja Bau, Antje Sucker, Eva Hadaschik, Florian Wirsdörfer, Helmut Hanenberg, Niklas Uhlenbrock, Daniel Rauh, Joanna Poźniak, Florian Rambow, Jean-Christophe Marine, Maike Effern, Nicole Glodde, Dirk Schadendorf, Jadwiga Jablonska, Michael Hölzel, Iris Helfrich

  • Early C-reactive protein kinetics predicts immunotherapy response in non-small cell lung cancer in the phase III OAK trial.

    JNCI cancer spectrum

    Authors: Jonas Saal, Tobias Bald, Markus Eckstein, Manuel Ritter, Peter Brossart, Jörg Ellinger, Michael Hölzel, Niklas Klümper

  • Reply to Jon Griffin. TIME for a Change? Multimarker Assessment of the Tumour Immune Microenvironment and Metastatic Site Biopsy to Improve Immunotherapy Response Prediction in Muscle-invasive Bladder Cancer. Eur Urol. 2023;43:143-4.

    European urology

    Authors: Niklas Klümper, Michael Hölzel, Markus Eckstein

  • Immune signatures predict development of autoimmune toxicity in patients with cancer treated with immune checkpoint inhibitors.

    Med (New York, N.Y.)

    Authors: Nicolas Gonzalo Nuñez, Fiamma Berner, Ekaterina Friebel, Susanne Unger, Nina Wyss, Julia Martinez Gomez, Mette-Triin Purde, Rebekka Niederer, Maximilian Porsch, Christa Lichtensteiger, Rafaela Kramer, Michael Erdmann, Christina Schmitt, Lucie Heinzerling, Marie-Therese Abdou, Julia Karbach, Dirk Schadendorf, Lisa Zimmer, Selma Ugurel, Niklas Klümper, Michael Hölzel, Laura Power, Stefanie Kreutmair, Mariaelena Capone, Gabriele Madonna, Lacin Cevhertas, Anja Heider, Teresa Amaral, Omar Hasan Ali, David Bomze, Florentia Dimitriou, Stefan Diem, Paolo Antonio Ascierto, Reinhard Dummer, Elke Jäger, Christoph Driessen, Mitchell Paul Levesque, Willem van de Veen, Markus Joerger, Martin Früh, Burkhard Becher, Lukas Flatz