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featured publications

  • The myeloid cell type I IFN system promotes antitumor immunity over pro-tumoral inflammation in cancer T-cell therapy.

    Clinical & translational immunology

    Authors: Janne Ruotsalainen, Dorys Lopez-Ramos, Meri Rogava, Naveen Shridhar, Nicole Glodde, Evelyn Gaffal, Michael Hölzel, Tobias Bald, Thomas Tüting

  • Downstream Neighbor of SON (DONSON) Expression Is Enhanced in Phenotypically Aggressive Prostate Cancers.

    Cancers

    Authors: Niklas Klümper, Marthe von Danwitz, Johannes Stein, Doris Schmidt, Anja Schmidt, Glen Kristiansen, Michael Muders, Michael Hölzel, Manuel Ritter, Abdullah Alajati, Jörg Ellinger

  • Functional screening identifies aryl hydrocarbon receptor as suppressor of lung cancer metastasis.

    Oncogenesis

    Authors: Silke Nothdurft, Clotilde Thumser-Henner, Frank Breitenbücher, Ross A Okimoto, Madeleine Dorsch, Christiane A Opitz, Ahmed Sadik, Charlotte Esser, Michael Hölzel, Saurabh Asthana, Jan Forster, Daniela Beisser, Sophie Kalmbach, Barbara M Grüner, Trever G Bivona, Alexander Schramm, Martin Schuler

  • CD155 on Tumor Cells Drives Resistance to Immunotherapy by Inducing the Degradation of the Activating Receptor CD226 in CD8 T Cells.

    Immunity

    Authors: Matthias Braun, Amelia Roman Aguilera, Ashmitha Sundarrajan, Dillon Corvino, Kimberley Stannard, Sophie Krumeich, Indrajit Das, Luize G Lima, Lizeth G Meza Guzman, Kunlun Li, Rui Li, Nazhifah Salim, Maria Villancanas Jorge, Sunyoung Ham, Gabrielle Kelly, Frank Vari, Ailin Lepletier, Ashwini Raghavendra, Sally Pearson, Jason Madore, Sebastien Jacquelin, Maike Effern, Brodie Quine, Lambros T Koufariotis, Mika Casey, Kyohei Nakamura, Eun Y Seo, Michael Hölzel, Matthias Geyer, Glen Kristiansen, Touraj Taheri, Elizabeth Ahern, Brett G M Hughes, James S Wilmott, Georgina V Long, Richard A Scolyer, Martin D Batstone, Jennifer Landsberg, Dimo Dietrich, Oltin T Pop, Lukas Flatz, William C Dougall, André Veillette, Sandra E Nicholson, Andreas Möller, Robert J Johnston, Ludovic Martinet, Mark J Smyth, Tobias Bald

  • BATF3 programs CD8 T cell memory.

    Nature immunology

    Authors: Marco A Ataide, Karl Komander, Konrad Knöpper, Annika E Peters, Hao Wu, Sarah Eickhoff, Tea Gogishvili, Justus Weber, Anika Grafen, Axel Kallies, Natalio Garbi, Hermann Einsele, Michael Hudecek, Georg Gasteiger, Michael Hölzel, Martin Vaeth, Wolfgang Kastenmüller

  • Cultivation of Clear Cell Renal Cell Carcinoma Patient-Derived Organoids in an Air-Liquid Interface System as a Tool for Studying Individualized Therapy.

    Frontiers in oncology

    Authors: Laura K Esser, Vittorio Branchi, Sonia Leonardelli, Natalie Pelusi, Adrian G Simon, Niklas Klümper, Jörg Ellinger, Stefan Hauser, Maria A Gonzalez-Carmona, Manuel Ritter, Glen Kristiansen, Hubert Schorle, Michael Hölzel, Marieta I Toma

  • Not Sweet: Glucocorticoids from Intratumoral Myeloid Cells Disable T Cells.

    Immunity

    Authors: Maike Effern, Michael Hölzel

  • Downstream neighbor of SON (DONSON) is associated with unfavorable survival across diverse cancers with oncogenic properties in clear cell renal cell carcinoma.

    Translational oncology

    Authors: Niklas Klümper, Iulia Blajan, Doris Schmidt, Glen Kristiansen, Marieta Toma, Michael Hölzel, Manuel Ritter, Jörg Ellinger

  • Top publication

    Adoptive T Cell Therapy Targeting Different Gene Products Reveals Diverse and Context-Dependent Immune Evasion in Melanoma.

    Immunity

    Authors: Maike Effern, Nicole Glodde, Matthias Braun, Jana Liebing, Helena N Boll, Michelle Yong, Emma Bawden, Daniel Hinze, Debby van den Boorn-Konijnenberg, Mila Daoud, Pia Aymans, Jennifer Landsberg, Mark J Smyth, Lukas Flatz, Thomas Tüting, Tobias Bald, Thomas Gebhardt, Michael Hölzel

  • Top publication

    Lipid-Droplet Formation Drives Pathogenic Group 2 Innate Lymphoid Cells in Airway Inflammation.

    Immunity

    Authors: Fotios Karagiannis, Schekufe Kharabi Masouleh, Klaus Wunderling, Jayagopi Surendar, Vanessa Schmitt, Alexander Kazakov, Marcel Michla, Michael Hölzel, Christoph Thiele, Christoph Wilhelm