Skip to main content

Publications

featured publications

  • L-RNA aptamer-based CXCL12 inhibition combined with radiotherapy and bevacizumab in newly-diagnosed glioblastoma: expansion of the phase I/II GLORIA trial.

    Nature communications

    Authors: Frank A Giordano, Julian P Layer, Roberta Turiello, Lea L Friker, Oriol Mirallas, Barbara E F Pregler, Anna-Laura Potthoff, Thomas Zeyen, Johannes Weller, Elena Sperk, Katharina Sahm, Christoph Oster, Sied Kebir, Peter Hambsch, Niklas Schäfer, Sebastian Kadzik, Mirjam Renovanz, Torsten Pietsch, Sotirios Bisdas, Juan Manuel Sepúlveda-Sánchez, Diego Gómez-Puerto, Maria Vieito, Michael Platten, Eleni Gkika, Oliver M Grauer, Ghazaleh Tabatabai, Matthias Schneider, Martin Glas, Clemens Seidel, Ulrich Herrlinger, Michael Hölzel

  • Telomere damage enhances immunogenicity of neuroblastoma and accelerates response to anti-PD-L1 treatment.

    Oncoimmunology

    Authors: Stefanie Höppner, Lisa Werr, Beata Szilagyi, Christoph Bartenhagen, Anna-Maria Hellmann, Carolina Rosswog, Emma Linden, Gerrit Primke, Yvonne Kahlert, Nadliv Ibruli, Nadine Hemstedt, Witali Lorenz, Johannes Brägelmann, Michael Hölzel, Matthias Fischer

  • Microglia-glioblastoma crosstalk mediates glioblastoma invasion at the far infiltration zone.

    Immunity

    Authors: Felix C Nebeling, Falko Fuhrmann, Manuel Mittag, Fabrizio Musacchio, Henrike Antony, Nala Gockel, Lea L Friker, Sonia Leonardelli, Severin Filser, Deli A, Miriam Stork, Daniele Bano, Torsten Pietsch, Frank A Giordano, Qihui Zhou, Simona Parrinello, Michael Hölzel, Ulrich Herrlinger, Paolo Salomoni, Martin Fuhrmann

  • Amplification Is a Frequent Event in Central Nervous System Metastases of Urothelial Carcinoma.

    European urology open science

    Authors: Richard Weiten, Constantin Rieger, Julian Heidenreich, Yuri Tolkach, Thomas Stehle, Florian Schmid, Teresa Schmidt, Martin Glas, Tobias Blau, Kathy Keyvani, Thomas Büttner, Viktor Grünwald, Michael Hölzel, Axel Heidenreich, Markus Eckstein, Niklas Klümper

  • High-salt diet induces immune-independent re-differentiation, metabolic shut down and cell cycle arrest of melanoma.

    Cell death & disease

    Authors: Clivia Lisowski, Natascha E Stumpf, Katarzyna Jobin, Daniela Klaus, Melanie Eichler, Ann-Kathrin Baumgart, Olena Babyak, Mirjam Meißner, Agnes Schröder, Patrick Neubert, Vanessa Schmitt, Marcel Michla, Süleyman Bozkurt, Jelena Zurkovic, Daniel Hinze, Jana Liebing, Matthias Eckhardt, Christoph Heuser, Lea Seep, Annkristin Heine, Janine Becker-Gotot, Christoph Thiele, Christian Münch, Thomas Becker, Jonathan Jantsch, Christoph Wilhelm, Michael Hölzel, Christian Kurts

  • SPACEc: a streamlined, interactive Python workflow for multiplexed image processing and analysis.

    Nature communications

    Authors: Yuqi Tan, Tim N Kempchen, Martin Becker, Maximilian Haist, Dorien Feyaerts, Jiaqi Liu, Marieta Toma, Yang Xiao, Graham Su, Andrew J Rech, Michael Hölzel, Rong Fan, John W Hickey, Garry P Nolan

  • Can NaCl predict or even enhance responses to immunotherapy in cancer?

    European journal of cancer (Oxford, England : 1990)

    Authors: Jonas Saal, Michael Hölzel, Niklas Klümper

  • Flow cytometry protocol for cell death analysis in glioblastoma organoids: A technical note.

    PloS one

    Authors: Anna-Laura Potthoff, Meng-Chun Hsieh, Ahmad Melhem, Susanna S Ng, Barbara E F Pregler, Annika Vieregge, Markus Raspe, Lea L Friker, Thomas Zeyen, Julian P Layer, Andreas Dolf, Marieta I Toma, Andreas Waha, Torsten Pietsch, Mike-Andrew Westhoff, Hartmut Vatter, Michael Hölzel, Ulrich Herrlinger, Matthias Schneider

  • MSH2, MSH6, MLH1, and PMS2 immunohistochemistry as highly sensitive screening method for DNA mismatch repair deficiency syndromes in pediatric high-grade glioma.

    Acta neuropathologica

    Authors: Lea L Friker, Thomas Perwein, Andreas Waha, Evelyn Dörner, Rebecca Klein, Mirjam Blattner-Johnson, Julian P Layer, Dominik Sturm, Gunther Nussbaumer, Robert Kwiecien, Isabel Spier, Stefan Aretz, Kornelius Kerl, Ulrike Hennewig, Marius Rohde, Axel Karow, Ingmar Bluemcke, Ann Kristin Schmitz, Harald Reinhard, Pablo Hernáiz Driever, Susanne Wendt, Annette Weiser, Ana S Guerreiro Stücklin, Nicolas U Gerber, André O von Bueren, Claudia Khurana, Norbert Jorch, Maria Wiese, Christian P Kratz, Matthias Eyrich, Michael Karremann, Ulrich Herrlinger, Michael Hölzel, David T W Jones, Marion Hoffmann, Torsten Pietsch, Gerrit H Gielen, Christof M Kramm

  • RNase T2 restricts TLR13-mediated autoinflammation in vivo.

    The Journal of experimental medicine

    Authors: Carlos Gomez-Diaz, Wilhelm Greulich, Benedikt Wefers, Meiyue Wang, Silvia Bolsega, Maike Effern, Daniel P Varga, Zhe Han, Minyi Chen, Marleen Bérouti, Natascia Leonardi, Ulrike Schillinger, Bernhard Holzmann, Arthur Liesz, Axel Roers, Michael Hölzel, Marijana Basic, Wolfgang Wurst, Veit Hornung