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Publications

featured publications

  • Functional Characterization of Cardiac Actin Mutants Causing Hypertrophic (p.A295S) and Dilated Cardiomyopathy (p.R312H and p.E361G).

    International journal of molecular sciences

    Authors: Roua Hassoun, Constanze Erdmann, Sebastian Schmitt, Setsuko Fujita-Becker, Andreas Mügge, Rasmus R Schröder, Matthias Geyer, Mina Borbor, Kornelia Jaquet, Nazha Hamdani, Hans Georg Mannherz

  • Transcriptional CDK Inhibitors as Potential Treatment Option for Testicular Germ Cell Tumors.

    Cancers

    Authors: Kai Funke, Robert Düster, Prince De-Graft Wilson, Lena Arévalo, Matthias Geyer, Hubert Schorle

  • Functional characterization of the human Cdk10/Cyclin Q complex.

    Open biology

    Authors: Robert Düster, Yanlong Ji, Kuan-Ting Pan, Henning Urlaub, Matthias Geyer

  • Structure-Stability Relationship of NLRP3 Inflammasome-Inhibiting Sulfonylureas.

    ACS omega

    Authors: Tim Keuler, Dominic Ferber, Michael Marleaux, Matthias Geyer, Michael Gütschow

  • Top publication

    Structure of the NLRP3 decamer bound to the cytokine release inhibitor CRID3.

    Nature

    Authors: Inga V Hochheiser, Michael Pilsl, Gregor Hagelueken, Jonas Moecking, Michael Marleaux, Rebecca Brinkschulte, Eicke Latz, Christoph Engel, Matthias Geyer

  • An Assay for the Seeding of Homotypic Pyrin Domain Filament Transitions.

    Methods in molecular biology (Clifton, N.J.)

    Authors: Inga V Hochheiser, Matthias Geyer

  • A Surface Plasmon Resonance-Based Strategy to Characterize Interactions of NLR Proteins with Associated Factors.

    Methods in molecular biology (Clifton, N.J.)

    Authors: Jonas Moecking, Matthias Geyer

  • Recessive NLRC4-Autoinflammatory Disease Reveals an Ulcerative Colitis Locus.

    Journal of clinical immunology

    Authors: Annemarie Steiner, Thomas Reygaerts, Alessandra Pontillo, Isabella Ceccherini, Jonas Moecking, Fiona Moghaddas, Sophia Davidson, Francesco Caroli, Alice Grossi, Fabio Fernandes Morato Castro, Jorge Kalil, Florian N Gohr, Florian I Schmidt, Eva Bartok, Thomas Zillinger, Gunther Hartmann, Matthias Geyer, Marco Gattorno, Leonardo Oliveira Mendonça, Seth L Masters

  • Abemaciclib is a potent inhibitor of DYRK1A and HIP kinases involved in transcriptional regulation.

    Nature communications

    Authors: Ines H Kaltheuner, Kanchan Anand, Jonas Moecking, Robert Düster, Jinhua Wang, Nathanael S Gray, Matthias Geyer

  • Four hypotrichosis families with mutations in the gene LSS presenting with and without neurodevelopmental phenotypes.

    American journal of medical genetics. Part A

    Authors: Nicole Cesarato, Maria Wehner, Mariam Ghughunishvili, Axel Schmidt, Daisy Axt, Holger Thiele, Michael J Lentze, Cristina Has, Matthias Geyer, Fitnat Buket Basmanav, Regina C Betz